Publicação
Recent advances on open fluidic systems for biomedical applications: A review
| Resumo: | Microfluidics has become an important tool to engineer microenvironments with high precision, comprising devices and methods for controlling and manipulating fluids at the submillimeter scale. A specific branch of microfluidics comprises open fluidic systems, which is mainly characterized by displaying a higher air/liquid interface when compared with traditional closed-channel setups. The use of open channel systems has enabled the design of singular architectures in devices that are simple to fabricate and to clean. Enhanced functionality and accessibility for liquid handling are additional advantages inputted to technologies based on open fluidics. While benchmarked against closed fluidics approaches, the use of directly accessible channels decreases the risk of clogging and bubble-driven flow perturbation. In this review, we discuss the advantages of open fluidics systems when compared to their closed fluidics counterparts. Platforms are analyzed in two separated groups based on different confinement principles: wall-based physical confinement and wettability-contrast confinement. The physical confinement group comprises both open and traditional microfluidics; examples based on open channels with rectangular and triangular cross-section, suspended microfluidics, and the use of narrow edge of a solid surface for fluid confinement are addressed. The second group covers (super)hydrophilic/(super)hydrophobic patterned surfaces, and examples based on polymer-, textile- and paper-based microfluidic devices are explored. The technologies described in this review are critically discussed concerning devices' performance and versatility, manufacturing techniques and fluid transport/manipulation methods. A gather-up of recent biomedical applications of open fluidics devices is also presented. |
|---|---|
| Autores principais: | Oliveira, Nuno Miguel Ribeiro |
| Outros Autores: | Vilabril, S.; Oliveira, M. B.; Reis, R. L.; Mano, J. F. |
| Assunto: | Fluid confinement Lab on a chip Microfluidics Open fluidics superhydrophilicity superhydrophobicity Ciências Médicas::Biotecnologia Médica Engenharia e Tecnologia::Biotecnologia Industrial |
| Ano: | 2019 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| _version_ | 1867438991942352896 |
|---|---|
| author | Oliveira, Nuno Miguel Ribeiro |
| author2 | Vilabril, S. Oliveira, M. B. Reis, R. L. Mano, J. F. |
| author2_role | author author author author |
| author_facet | Oliveira, Nuno Miguel Ribeiro Vilabril, S. Oliveira, M. B. Reis, R. L. Mano, J. F. |
| author_role | author |
| contributor_name_str_mv | RepositóriUM - Universidade do Minho |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Oliveira, Nuno Miguel Ribeiro\"},{\"Person.name\":\"Vilabril, S.\"},{\"Person.name\":\"Oliveira, M. B.\"},{\"Person.name\":\"Reis, R. L.\"},{\"Person.name\":\"Mano, J. F.\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | RepositóriUM - Universidade do Minho |
| datacite.creators.creator.creatorName.fl_str_mv | Oliveira, Nuno Miguel Ribeiro Vilabril, S. Oliveira, M. B. Reis, R. L. Mano, J. F. |
| datacite.date.Accepted.fl_str_mv | 2019-04-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2019-02-20T12:05:36Z |
| datacite.date.embargoed.fl_str_mv | 2019-02-20T12:05:36Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Fluid confinement Lab on a chip Microfluidics Open fluidics superhydrophilicity superhydrophobicity Ciências Médicas::Biotecnologia Médica Engenharia e Tecnologia::Biotecnologia Industrial |
| datacite.titles.title.fl_str_mv | Recent advances on open fluidic systems for biomedical applications: A review |
| dc.contributor.none.fl_str_mv | RepositóriUM - Universidade do Minho |
| dc.creator.none.fl_str_mv | Oliveira, Nuno Miguel Ribeiro Vilabril, S. Oliveira, M. B. Reis, R. L. Mano, J. F. |
| dc.date.Accepted.fl_str_mv | 2019-04-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2019-02-20T12:05:36Z |
| dc.date.embargoed.fl_str_mv | 2019-02-20T12:05:36Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | https://hdl.handle.net/1822/59127 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Elsevier |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | Fluid confinement Lab on a chip Microfluidics Open fluidics superhydrophilicity superhydrophobicity Ciências Médicas::Biotecnologia Médica Engenharia e Tecnologia::Biotecnologia Industrial |
| dc.title.fl_str_mv | Recent advances on open fluidic systems for biomedical applications: A review |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Microfluidics has become an important tool to engineer microenvironments with high precision, comprising devices and methods for controlling and manipulating fluids at the submillimeter scale. A specific branch of microfluidics comprises open fluidic systems, which is mainly characterized by displaying a higher air/liquid interface when compared with traditional closed-channel setups. The use of open channel systems has enabled the design of singular architectures in devices that are simple to fabricate and to clean. Enhanced functionality and accessibility for liquid handling are additional advantages inputted to technologies based on open fluidics. While benchmarked against closed fluidics approaches, the use of directly accessible channels decreases the risk of clogging and bubble-driven flow perturbation. In this review, we discuss the advantages of open fluidics systems when compared to their closed fluidics counterparts. Platforms are analyzed in two separated groups based on different confinement principles: wall-based physical confinement and wettability-contrast confinement. The physical confinement group comprises both open and traditional microfluidics; examples based on open channels with rectangular and triangular cross-section, suspended microfluidics, and the use of narrow edge of a solid surface for fluid confinement are addressed. The second group covers (super)hydrophilic/(super)hydrophobic patterned surfaces, and examples based on polymer-, textile- and paper-based microfluidic devices are explored. The technologies described in this review are critically discussed concerning devices' performance and versatility, manufacturing techniques and fluid transport/manipulation methods. A gather-up of recent biomedical applications of open fluidics devices is also presented. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| fulltext.url.fl_str_mv | https://repositorium.uminho.pt/bitstreams/74f24b67-7e8a-4a16-bc62-54cdf2f31ce6/download |
| id | rum_e1ae955bb6cf5784d71fdfd6fc6274e8 |
| identifier.url.fl_str_mv | https://hdl.handle.net/1822/59127 |
| instacron_str | repositorium |
| institution | Universidade do Minho |
| instname_str | Universidade do Minho |
| language | eng |
| network_acronym_str | rum |
| network_name_str | RepositóriUM - Universidade do Minho |
| oai_identifier_str | oai:repositorium.uminho.pt:1822/59127 |
| organization_str_mv | urn:organizationAcronym:repositorium |
| person_str_mv | Oliveira, Nuno Miguel Ribeiro Vilabril, S. Oliveira, M. B. Reis, R. L. Mano, J. F. |
| publishDate | 2019 |
| publisher.none.fl_str_mv | Elsevier |
| reponame_str | RepositóriUM - Universidade do Minho |
| repository_id_str | urn:repositoryAcronym:rum |
| service_str_mv | urn:repositoryAcronym:rum |
| spelling | engElsevierporMicrofluidics has become an important tool to engineer microenvironments with high precision, comprising devices and methods for controlling and manipulating fluids at the submillimeter scale. A specific branch of microfluidics comprises open fluidic systems, which is mainly characterized by displaying a higher air/liquid interface when compared with traditional closed-channel setups. The use of open channel systems has enabled the design of singular architectures in devices that are simple to fabricate and to clean. Enhanced functionality and accessibility for liquid handling are additional advantages inputted to technologies based on open fluidics. While benchmarked against closed fluidics approaches, the use of directly accessible channels decreases the risk of clogging and bubble-driven flow perturbation. In this review, we discuss the advantages of open fluidics systems when compared to their closed fluidics counterparts. Platforms are analyzed in two separated groups based on different confinement principles: wall-based physical confinement and wettability-contrast confinement. The physical confinement group comprises both open and traditional microfluidics; examples based on open channels with rectangular and triangular cross-section, suspended microfluidics, and the use of narrow edge of a solid surface for fluid confinement are addressed. The second group covers (super)hydrophilic/(super)hydrophobic patterned surfaces, and examples based on polymer-, textile- and paper-based microfluidic devices are explored. The technologies described in this review are critically discussed concerning devices' performance and versatility, manufacturing techniques and fluid transport/manipulation methods. A gather-up of recent biomedical applications of open fluidics devices is also presented.application/pdfporRecent advances on open fluidic systems for biomedical applications: A reviewOliveira, Nuno Miguel RibeiroVilabril, S.Oliveira, M. B.Reis, R. L.Mano, J. F.HostingInstitutionOrganizationalRepositóriUM - Universidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.ptCITATIONOliveira N. M., Vilabril S., Oliveira M. B., Reis R. L., Mano J. F. Recent advances on open fluidic systems for biomedical applications: A review, Materials Science and Engineering C, Vol. 97, pp. 851-863, doi:10.1016/j.msec.2018.12.040, 2018.PMID30678977ISSNIsPartOf0928-4931DOIIsPartOf10.1016/j.msec.2018.12.0402019-02-20T12:05:36Z2019-042018-022019-01-31T15:51:11Z2019-04-01T00:00:00ZHandlehttps://hdl.handle.net/1822/59127http://purl.org/coar/access_right/c_abf2open accessFluid confinementLab on a chipMicrofluidicsOpen fluidicssuperhydrophilicitysuperhydrophobicityhttp://www.oecd.org/science/inno/38235147.pdfFields of Science and Technology (FOS)Ciências Médicas::Biotecnologia Médicahttp://www.oecd.org/science/inno/38235147.pdfFields of Science and Technology (FOS)Engenharia e Tecnologia::Biotecnologia Industrial2667735 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://repositorium.uminho.pt/bitstreams/74f24b67-7e8a-4a16-bc62-54cdf2f31ce6/download |
| spellingShingle | Recent advances on open fluidic systems for biomedical applications: A review Oliveira, Nuno Miguel Ribeiro Fluid confinement Lab on a chip Microfluidics Open fluidics superhydrophilicity superhydrophobicity Ciências Médicas::Biotecnologia Médica Engenharia e Tecnologia::Biotecnologia Industrial |
| status | SINGLETON |
| subject.fl_str_mv | Fluid confinement Lab on a chip Microfluidics Open fluidics superhydrophilicity superhydrophobicity |
| subject.other.fl_str_mv | Ciências Médicas::Biotecnologia Médica Engenharia e Tecnologia::Biotecnologia Industrial |
| title | Recent advances on open fluidic systems for biomedical applications: A review |
| title_full | Recent advances on open fluidic systems for biomedical applications: A review |
| title_fullStr | Recent advances on open fluidic systems for biomedical applications: A review |
| title_full_unstemmed | Recent advances on open fluidic systems for biomedical applications: A review |
| title_short | Recent advances on open fluidic systems for biomedical applications: A review |
| title_sort | Recent advances on open fluidic systems for biomedical applications: A review |
| topic | Fluid confinement Lab on a chip Microfluidics Open fluidics superhydrophilicity superhydrophobicity Ciências Médicas::Biotecnologia Médica Engenharia e Tecnologia::Biotecnologia Industrial |
| topic_facet | Fluid confinement Lab on a chip Microfluidics Open fluidics superhydrophilicity superhydrophobicity Ciências Médicas::Biotecnologia Médica Engenharia e Tecnologia::Biotecnologia Industrial |
| url | https://hdl.handle.net/1822/59127 |
| visible | 1 |