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Biomass and microbial lipids production by Yarrowia lipolytica W29 from eucalyptus bark hydrolysate

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Resumo:Using lignocellulosic biomass hydrolysate as a renewable and abundant feedstock for microbial lipids production is a sustainable and economic high-potential approach. This study investigated the potential of the oleaginous yeast Yarrowia lipolytica to produce lipids-rich biomass from eucalyptus bark hydrolysate (EBH) obtained by enzymatic hydrolysis of the biomass pretreated by steam explosion. The effect of EBH concentration (undiluted and 1:3 v/v diluted) and medium supplementation (CSL and KH2PO4) was evaluated in Erlenmeyer flasks and lab-scale stirred tank bioreactor, respectively. Additionally, the effect of volumetric oxygen transfer coefficient (kLa) and mode of operation (batch and two-stage repeated batch) was also assessed in the bioreactor. Under the best experimental conditions (undiluted EBH, 2gL1 CSL, 1.8gL1(NH4)2SO4, and kLa of 66 h1), Y. lipolytica W29 grown in batch cultures accumulated 26 % (w/w) of intracellular lipids, corresponding to 5.6gL1 of concentration. Lipids of Y. lipolytica were highly unsaturated and mainly composed of oleic acid (48 %), followed by palmitoleic (20 %), linoleic (17 %) and palmitic acids (14 %). This composition of Y. lipolytica lipids suggests their potential use as feedstock for biodiesel (a renewable biofuel). This work demonstrated the robust features of Y. lipolytica W29 as a potential lipids production platform to implement lignocellulose-based biorefineries.
Autores principais:Dias, Bruna
Outros Autores:Lopes, Marlene; Fernandes, Helena; Marques, Susana; Gírio, Francisco; Belo, Isabel
Assunto:Eucalyptus bark hydrolysate Microbial lipids Volumetric oxygen transfer coefficient Yarrowia lipolytica
Ano:2024
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho
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author Dias, Bruna
author2 Lopes, Marlene
Fernandes, Helena
Marques, Susana
Gírio, Francisco
Belo, Isabel
author2_role author
author
author
author
author
author_facet Dias, Bruna
Lopes, Marlene
Fernandes, Helena
Marques, Susana
Gírio, Francisco
Belo, Isabel
author_role author
contributor_name_str_mv Universidade do Minho
country_str PT
creators_json_txt [{\"Person.name\":\"Dias, Bruna\"},{\"Person.name\":\"Lopes, Marlene\"},{\"Person.name\":\"Fernandes, Helena\"},{\"Person.name\":\"Marques, Susana\"},{\"Person.name\":\"Gírio, Francisco\"},{\"Person.name\":\"Belo, Isabel\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Universidade do Minho
datacite.creators.creator.creatorName.fl_str_mv Dias, Bruna
Lopes, Marlene
Fernandes, Helena
Marques, Susana
Gírio, Francisco
Belo, Isabel
datacite.date.Accepted.fl_str_mv 2024-04-01T00:00:00Z
datacite.date.available.fl_str_mv 2024-03-12T17:51:56Z
datacite.date.embargoed.fl_str_mv 2024-03-12T17:51:56Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Eucalyptus bark hydrolysate
Microbial lipids
Volumetric oxygen transfer coefficient
Yarrowia lipolytica
datacite.titles.title.fl_str_mv Biomass and microbial lipids production by Yarrowia lipolytica W29 from eucalyptus bark hydrolysate
dc.contributor.none.fl_str_mv Universidade do Minho
dc.creator.none.fl_str_mv Dias, Bruna
Lopes, Marlene
Fernandes, Helena
Marques, Susana
Gírio, Francisco
Belo, Isabel
dc.date.Accepted.fl_str_mv 2024-04-01T00:00:00Z
dc.date.available.fl_str_mv 2024-03-12T17:51:56Z
dc.date.embargoed.fl_str_mv 2024-03-12T17:51:56Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv https://hdl.handle.net/1822/89459
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Elsevier
dc.rights.cclincense.fl_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.rights.copyright.fl_str_mv openAccess
dc.subject.none.fl_str_mv Eucalyptus bark hydrolysate
Microbial lipids
Volumetric oxygen transfer coefficient
Yarrowia lipolytica
dc.title.fl_str_mv Biomass and microbial lipids production by Yarrowia lipolytica W29 from eucalyptus bark hydrolysate
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description Using lignocellulosic biomass hydrolysate as a renewable and abundant feedstock for microbial lipids production is a sustainable and economic high-potential approach. This study investigated the potential of the oleaginous yeast Yarrowia lipolytica to produce lipids-rich biomass from eucalyptus bark hydrolysate (EBH) obtained by enzymatic hydrolysis of the biomass pretreated by steam explosion. The effect of EBH concentration (undiluted and 1:3 v/v diluted) and medium supplementation (CSL and KH2PO4) was evaluated in Erlenmeyer flasks and lab-scale stirred tank bioreactor, respectively. Additionally, the effect of volumetric oxygen transfer coefficient (kLa) and mode of operation (batch and two-stage repeated batch) was also assessed in the bioreactor. Under the best experimental conditions (undiluted EBH, 2gL1 CSL, 1.8gL1(NH4)2SO4, and kLa of 66 h1), Y. lipolytica W29 grown in batch cultures accumulated 26 % (w/w) of intracellular lipids, corresponding to 5.6gL1 of concentration. Lipids of Y. lipolytica were highly unsaturated and mainly composed of oleic acid (48 %), followed by palmitoleic (20 %), linoleic (17 %) and palmitic acids (14 %). This composition of Y. lipolytica lipids suggests their potential use as feedstock for biodiesel (a renewable biofuel). This work demonstrated the robust features of Y. lipolytica W29 as a potential lipids production platform to implement lignocellulose-based biorefineries.
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eu_rights_str_mv openAccess
format article
fulltext.url.fl_str_mv https://prod-dspace.uminho.pt/bitstreams/1bbdca84-a0bf-4a5e-835e-00c32a47436c/download
id rum_eef3f7f2df9c43dd8a99c2aed2bddfb9
identifier.url.fl_str_mv https://hdl.handle.net/1822/89459
instacron_str repositorium
institution Universidade do Minho
instname_str Universidade do Minho
language eng
network_acronym_str rum
network_name_str RepositóriUM - Universidade do Minho
oai_identifier_str oai:repositorium.uminho.pt:1822/89459
organization_str_mv urn:organizationAcronym:repositorium
person_str_mv Dias, Bruna
Lopes, Marlene
Fernandes, Helena
Marques, Susana
Gírio, Francisco
Belo, Isabel
publishDate 2024
publisher.none.fl_str_mv Elsevier
reponame_str RepositóriUM - Universidade do Minho
repository_id_str urn:repositoryAcronym:rum
service_str_mv urn:repositoryAcronym:rum
spelling engElsevierporUsing lignocellulosic biomass hydrolysate as a renewable and abundant feedstock for microbial lipids production is a sustainable and economic high-potential approach. This study investigated the potential of the oleaginous yeast Yarrowia lipolytica to produce lipids-rich biomass from eucalyptus bark hydrolysate (EBH) obtained by enzymatic hydrolysis of the biomass pretreated by steam explosion. The effect of EBH concentration (undiluted and 1:3 v/v diluted) and medium supplementation (CSL and KH2PO4) was evaluated in Erlenmeyer flasks and lab-scale stirred tank bioreactor, respectively. Additionally, the effect of volumetric oxygen transfer coefficient (kLa) and mode of operation (batch and two-stage repeated batch) was also assessed in the bioreactor. Under the best experimental conditions (undiluted EBH, 2gL1 CSL, 1.8gL1(NH4)2SO4, and kLa of 66 h1), Y. lipolytica W29 grown in batch cultures accumulated 26 % (w/w) of intracellular lipids, corresponding to 5.6gL1 of concentration. Lipids of Y. lipolytica were highly unsaturated and mainly composed of oleic acid (48 %), followed by palmitoleic (20 %), linoleic (17 %) and palmitic acids (14 %). This composition of Y. lipolytica lipids suggests their potential use as feedstock for biodiesel (a renewable biofuel). This work demonstrated the robust features of Y. lipolytica W29 as a potential lipids production platform to implement lignocellulose-based biorefineries.application/pdfporBiomass and microbial lipids production by Yarrowia lipolytica W29 from eucalyptus bark hydrolysateDias, BrunaLopes, MarleneFernandes, HelenaMarques, SusanaGírio, FranciscoBelo, IsabelHostingInstitutionOrganizationalUniversidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.ptISSNIsPartOf0960-1481DOIIsPartOf10.1016/j.renene.2024.1201732024-03-12T17:51:56Z2024-042024-03-09T10:29:27Z2024-04-01T00:00:00ZHandlehttps://hdl.handle.net/1822/89459http://purl.org/coar/access_right/c_abf2open accessEucalyptus bark hydrolysateMicrobial lipidsVolumetric oxygen transfer coefficientYarrowia lipolytica992667 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal article2024-04http://creativecommons.org/licenses/by-nc-nd/4.0/openAccesshttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://prod-dspace.uminho.pt/bitstreams/1bbdca84-a0bf-4a5e-835e-00c32a47436c/download
spellingShingle Biomass and microbial lipids production by Yarrowia lipolytica W29 from eucalyptus bark hydrolysate
Dias, Bruna
Eucalyptus bark hydrolysate
Microbial lipids
Volumetric oxygen transfer coefficient
Yarrowia lipolytica
status SINGLETON
subject.fl_str_mv Eucalyptus bark hydrolysate
Microbial lipids
Volumetric oxygen transfer coefficient
Yarrowia lipolytica
title Biomass and microbial lipids production by Yarrowia lipolytica W29 from eucalyptus bark hydrolysate
title_full Biomass and microbial lipids production by Yarrowia lipolytica W29 from eucalyptus bark hydrolysate
title_fullStr Biomass and microbial lipids production by Yarrowia lipolytica W29 from eucalyptus bark hydrolysate
title_full_unstemmed Biomass and microbial lipids production by Yarrowia lipolytica W29 from eucalyptus bark hydrolysate
title_short Biomass and microbial lipids production by Yarrowia lipolytica W29 from eucalyptus bark hydrolysate
title_sort Biomass and microbial lipids production by Yarrowia lipolytica W29 from eucalyptus bark hydrolysate
topic Eucalyptus bark hydrolysate
Microbial lipids
Volumetric oxygen transfer coefficient
Yarrowia lipolytica
topic_facet Eucalyptus bark hydrolysate
Microbial lipids
Volumetric oxygen transfer coefficient
Yarrowia lipolytica
url https://hdl.handle.net/1822/89459
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