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Production of fructo-oligosaccharides by Aspergillus ibericus and their chemical characterization

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Resumo:A great demand for prebiotics is driving the search for new sources of fructo-oligosaccharides (FOS) producers and for FOS with differentiated functionalities. In the present work, FOS production by a new isolated strain of Aspergillus ibericus was evaluated. The temperature of fermentation and initial pH were optimized in shaken flask to yield a maximal FOS production, through a central composite experimental design. FOS were produced in a one-step bioprocess using the whole cells of the microorganism. The model (R2 = 0.918) predicted a yield of 0.56, experimentally 0.53 ± 0.03 gFOS.ginitial sucrose1 was obtained (37.0 °C and a pH of 6.2). A yield of 0.64 ± 0.02 gFOS.ginitial sucrose1 was obtained in the bioreactor, at 38 h, with a content of 118 ± 4 g.L1 in FOS and a purity of 56 ± 3%. The chemical structure of the FOS produced by A. ibericus was determined by HPLC and NMR. FOS were identified as 1-kestose, nystose, and 1F-fructofuranosylnystose. In conclusion, A. ibericus was found to be a good alternative FOS producer.
Autores principais:Gonçalves, Clarisse Salomé Nobre
Outros Autores:Alves Filho, E. G.; Fernandes, Fabiano A. N.; Brito, Edy S.; Rodrigues, S.; Teixeira, J. A.; Rodrigues, L. R.
Assunto:Fructo-oligosaccharides Aspergillus ibericus Chemical structure Experimental design Production yield optimization
Ano:2018
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho
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author Gonçalves, Clarisse Salomé Nobre
author2 Alves Filho, E. G.
Fernandes, Fabiano A. N.
Brito, Edy S.
Rodrigues, S.
Teixeira, J. A.
Rodrigues, L. R.
author2_role author
author
author
author
author
author
author_facet Gonçalves, Clarisse Salomé Nobre
Alves Filho, E. G.
Fernandes, Fabiano A. N.
Brito, Edy S.
Rodrigues, S.
Teixeira, J. A.
Rodrigues, L. R.
author_role author
contributor_name_str_mv Universidade do Minho
country_str PT
creators_json_txt [{\"Person.name\":\"Gonçalves, Clarisse Salomé Nobre\"},{\"Person.name\":\"Alves Filho, E. G.\"},{\"Person.name\":\"Fernandes, Fabiano A. N.\"},{\"Person.name\":\"Brito, Edy S.\"},{\"Person.name\":\"Rodrigues, S.\"},{\"Person.name\":\"Teixeira, J. A.\"},{\"Person.name\":\"Rodrigues, L. R.\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Universidade do Minho
datacite.creators.creator.creatorName.fl_str_mv Gonçalves, Clarisse Salomé Nobre
Alves Filho, E. G.
Fernandes, Fabiano A. N.
Brito, Edy S.
Rodrigues, S.
Teixeira, J. A.
Rodrigues, L. R.
datacite.date.Accepted.fl_str_mv 2018-03-01T00:00:00Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Fructo-oligosaccharides
Aspergillus ibericus
Chemical structure
Experimental design
Production yield optimization
datacite.titles.title.fl_str_mv Production of fructo-oligosaccharides by Aspergillus ibericus and their chemical characterization
dc.contributor.none.fl_str_mv Universidade do Minho
dc.creator.none.fl_str_mv Gonçalves, Clarisse Salomé Nobre
Alves Filho, E. G.
Fernandes, Fabiano A. N.
Brito, Edy S.
Rodrigues, S.
Teixeira, J. A.
Rodrigues, L. R.
dc.date.Accepted.fl_str_mv 2018-03-01T00:00:00Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv https://hdl.handle.net/1822/46766
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Elsevier
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.subject.none.fl_str_mv Fructo-oligosaccharides
Aspergillus ibericus
Chemical structure
Experimental design
Production yield optimization
dc.title.fl_str_mv Production of fructo-oligosaccharides by Aspergillus ibericus and their chemical characterization
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description A great demand for prebiotics is driving the search for new sources of fructo-oligosaccharides (FOS) producers and for FOS with differentiated functionalities. In the present work, FOS production by a new isolated strain of Aspergillus ibericus was evaluated. The temperature of fermentation and initial pH were optimized in shaken flask to yield a maximal FOS production, through a central composite experimental design. FOS were produced in a one-step bioprocess using the whole cells of the microorganism. The model (R2 = 0.918) predicted a yield of 0.56, experimentally 0.53 ± 0.03 gFOS.ginitial sucrose1 was obtained (37.0 °C and a pH of 6.2). A yield of 0.64 ± 0.02 gFOS.ginitial sucrose1 was obtained in the bioreactor, at 38 h, with a content of 118 ± 4 g.L1 in FOS and a purity of 56 ± 3%. The chemical structure of the FOS produced by A. ibericus was determined by HPLC and NMR. FOS were identified as 1-kestose, nystose, and 1F-fructofuranosylnystose. In conclusion, A. ibericus was found to be a good alternative FOS producer.
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eu_rights_str_mv openAccess
format article
fulltext.url.fl_str_mv https://prod-dspace.uminho.pt/bitstreams/62fd77d1-6bb5-4426-b322-d08171ee8e8b/download
id rum_f5b216afcf86621d07ad19082bf64ac4
identifier.url.fl_str_mv https://hdl.handle.net/1822/46766
instacron_str repositorium
institution Universidade do Minho
instname_str Universidade do Minho
language eng
network_acronym_str rum
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oai_identifier_str oai:repositorium.uminho.pt:1822/46766
organization_str_mv urn:organizationAcronym:repositorium
person_str_mv Gonçalves, Clarisse Salomé Nobre
Alves Filho, E. G.
Fernandes, Fabiano A. N.
Brito, Edy S.
Rodrigues, S.
Teixeira, J. A.
Rodrigues, L. R.
publishDate 2018
publisher.none.fl_str_mv Elsevier
reponame_str RepositóriUM - Universidade do Minho
repository_id_str urn:repositoryAcronym:rum
service_str_mv urn:repositoryAcronym:rum
spelling engElsevierporA great demand for prebiotics is driving the search for new sources of fructo-oligosaccharides (FOS) producers and for FOS with differentiated functionalities. In the present work, FOS production by a new isolated strain of Aspergillus ibericus was evaluated. The temperature of fermentation and initial pH were optimized in shaken flask to yield a maximal FOS production, through a central composite experimental design. FOS were produced in a one-step bioprocess using the whole cells of the microorganism. The model (R2 = 0.918) predicted a yield of 0.56, experimentally 0.53 ± 0.03 gFOS.ginitial sucrose1 was obtained (37.0 °C and a pH of 6.2). A yield of 0.64 ± 0.02 gFOS.ginitial sucrose1 was obtained in the bioreactor, at 38 h, with a content of 118 ± 4 g.L1 in FOS and a purity of 56 ± 3%. The chemical structure of the FOS produced by A. ibericus was determined by HPLC and NMR. FOS were identified as 1-kestose, nystose, and 1F-fructofuranosylnystose. In conclusion, A. ibericus was found to be a good alternative FOS producer.application/pdfporProduction of fructo-oligosaccharides by Aspergillus ibericus and their chemical characterizationGonçalves, Clarisse Salomé NobreAlves Filho, E. G.Fernandes, Fabiano A. N.Brito, Edy S.Rodrigues, S.Teixeira, J. A.Rodrigues, L. R.HostingInstitutionOrganizationalUniversidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.ptISSNIsPartOf0023-6438DOIIsPartOf10.1016/j.lwt.2017.10.0152018-032017-10-22T12:08:05Z2018-03-01T00:00:00ZHandlehttps://hdl.handle.net/1822/46766http://purl.org/coar/access_right/c_abf2open accessFructo-oligosaccharidesAspergillus ibericusChemical structureExperimental designProduction yield optimization551391 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://prod-dspace.uminho.pt/bitstreams/62fd77d1-6bb5-4426-b322-d08171ee8e8b/download
spellingShingle Production of fructo-oligosaccharides by Aspergillus ibericus and their chemical characterization
Gonçalves, Clarisse Salomé Nobre
Fructo-oligosaccharides
Aspergillus ibericus
Chemical structure
Experimental design
Production yield optimization
status SINGLETON
subject.fl_str_mv Fructo-oligosaccharides
Aspergillus ibericus
Chemical structure
Experimental design
Production yield optimization
title Production of fructo-oligosaccharides by Aspergillus ibericus and their chemical characterization
title_full Production of fructo-oligosaccharides by Aspergillus ibericus and their chemical characterization
title_fullStr Production of fructo-oligosaccharides by Aspergillus ibericus and their chemical characterization
title_full_unstemmed Production of fructo-oligosaccharides by Aspergillus ibericus and their chemical characterization
title_short Production of fructo-oligosaccharides by Aspergillus ibericus and their chemical characterization
title_sort Production of fructo-oligosaccharides by Aspergillus ibericus and their chemical characterization
topic Fructo-oligosaccharides
Aspergillus ibericus
Chemical structure
Experimental design
Production yield optimization
topic_facet Fructo-oligosaccharides
Aspergillus ibericus
Chemical structure
Experimental design
Production yield optimization
url https://hdl.handle.net/1822/46766
visible 1