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Co-culture of endothelial and smooth muscle cells for the development of blood vessel constructs

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Resumo:[Excerpt] Diseases of the blood vessels, particularly of small diameter arteries are responsible for most of deaths in developing and developed countries. The number of operations using arterial prostheses and of small calibre vascular bypass reaches enormous values every year. With the limited availability of functional autologous vessels the need for new strategies to develop artificial blood vessels is increasing. The aim of this work is to develop constructs composed of a polymeric support with two different surfaces, displaying distinct surface properties, to seed endothelial (ECs) and smooth muscle cells (SMCs) with the purpose of obtaining an artificial blood vessel substitute. [...]
Autores principais:Szymczyk, Wojciech
Outros Autores:Araújo, J. V.; Martins, Albino; Pinho, E.; Neves, N. M.; Marques, A. P.; Reis, R. L.
Assunto:Engenharia e Tecnologia::Biotecnologia Industrial
Ano:2008
País:Portugal
Tipo de documento:outro
Tipo de acesso:acesso aberto
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho
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author Szymczyk, Wojciech
author2 Araújo, J. V.
Martins, Albino
Pinho, E.
Neves, N. M.
Marques, A. P.
Reis, R. L.
author2_role author
author
author
author
author
author
author_facet Szymczyk, Wojciech
Araújo, J. V.
Martins, Albino
Pinho, E.
Neves, N. M.
Marques, A. P.
Reis, R. L.
author_role author
contributor_name_str_mv RepositóriUM - Universidade do Minho
country_str PT
creators_json_txt [{\"Person.name\":\"Szymczyk, Wojciech\"},{\"Person.name\":\"Araújo, J. V.\"},{\"Person.name\":\"Martins, Albino\"},{\"Person.name\":\"Pinho, E.\"},{\"Person.name\":\"Neves, N. M.\"},{\"Person.name\":\"Marques, A. P.\"},{\"Person.name\":\"Reis, R. L.\"}]
datacite.contributors.contributor.contributorName.fl_str_mv RepositóriUM - Universidade do Minho
datacite.creators.creator.creatorName.fl_str_mv Szymczyk, Wojciech
Araújo, J. V.
Martins, Albino
Pinho, E.
Neves, N. M.
Marques, A. P.
Reis, R. L.
datacite.date.Accepted.fl_str_mv 2008-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2019-02-19T12:27:00Z
datacite.date.embargoed.fl_str_mv 2019-02-19T12:27:00Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Engenharia e Tecnologia::Biotecnologia Industrial
datacite.titles.title.fl_str_mv Co-culture of endothelial and smooth muscle cells for the development of blood vessel constructs
dc.contributor.none.fl_str_mv RepositóriUM - Universidade do Minho
dc.creator.none.fl_str_mv Szymczyk, Wojciech
Araújo, J. V.
Martins, Albino
Pinho, E.
Neves, N. M.
Marques, A. P.
Reis, R. L.
dc.date.Accepted.fl_str_mv 2008-01-01T00:00:00Z
dc.date.available.fl_str_mv 2019-02-19T12:27:00Z
dc.date.embargoed.fl_str_mv 2019-02-19T12:27:00Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv https://hdl.handle.net/1822/59110
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Mary Ann Liebert Inc.
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.subject.none.fl_str_mv Engenharia e Tecnologia::Biotecnologia Industrial
dc.title.fl_str_mv Co-culture of endothelial and smooth muscle cells for the development of blood vessel constructs
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_1843
description [Excerpt] Diseases of the blood vessels, particularly of small diameter arteries are responsible for most of deaths in developing and developed countries. The number of operations using arterial prostheses and of small calibre vascular bypass reaches enormous values every year. With the limited availability of functional autologous vessels the need for new strategies to develop artificial blood vessels is increasing. The aim of this work is to develop constructs composed of a polymeric support with two different surfaces, displaying distinct surface properties, to seed endothelial (ECs) and smooth muscle cells (SMCs) with the purpose of obtaining an artificial blood vessel substitute. [...]
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eu_rights_str_mv openAccess
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fulltext.url.fl_str_mv https://repositorium.uminho.pt/bitstreams/593f5f80-0b03-4911-a4f4-a16981dca2ca/download
id rum_fad77856499de2c125b9fa21280a1d64
identifier.url.fl_str_mv https://hdl.handle.net/1822/59110
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instname_str Universidade do Minho
language eng
network_acronym_str rum
network_name_str RepositóriUM - Universidade do Minho
oai_identifier_str oai:repositorium.uminho.pt:1822/59110
organization_str_mv urn:organizationAcronym:repositorium
person_str_mv Szymczyk, Wojciech
Araújo, J. V.
Martins, Albino
Pinho, E.
Neves, N. M.
Marques, A. P.
Reis, R. L.
publishDate 2008
publisher.none.fl_str_mv Mary Ann Liebert Inc.
reponame_str RepositóriUM - Universidade do Minho
repository_id_str urn:repositoryAcronym:rum
service_str_mv urn:repositoryAcronym:rum
spelling engMary Ann Liebert Inc.por[Excerpt] Diseases of the blood vessels, particularly of small diameter arteries are responsible for most of deaths in developing and developed countries. The number of operations using arterial prostheses and of small calibre vascular bypass reaches enormous values every year. With the limited availability of functional autologous vessels the need for new strategies to develop artificial blood vessels is increasing. The aim of this work is to develop constructs composed of a polymeric support with two different surfaces, displaying distinct surface properties, to seed endothelial (ECs) and smooth muscle cells (SMCs) with the purpose of obtaining an artificial blood vessel substitute. [...]application/pdfporCo-culture of endothelial and smooth muscle cells for the development of blood vessel constructsSzymczyk, WojciechAraújo, J. V.Martins, AlbinoPinho, E.Neves, N. M.Marques, A. P.Reis, R. L.HostingInstitutionOrganizationalRepositóriUM - Universidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.ptISSNIsPartOf1937-33412019-02-19T12:27:00Z20082008-01-01T00:00:00ZHandlehttps://hdl.handle.net/1822/59110http://purl.org/coar/access_right/c_abf2open accesshttp://www.oecd.org/science/inno/38235147.pdfFields of Science and Technology (FOS)Engenharia e Tecnologia::Biotecnologia Industrial43914 bytesother research producthttp://purl.org/coar/resource_type/c_1843otherhttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://repositorium.uminho.pt/bitstreams/593f5f80-0b03-4911-a4f4-a16981dca2ca/download
spellingShingle Co-culture of endothelial and smooth muscle cells for the development of blood vessel constructs
Szymczyk, Wojciech
Engenharia e Tecnologia::Biotecnologia Industrial
status SINGLETON
subject.other.fl_str_mv Engenharia e Tecnologia::Biotecnologia Industrial
title Co-culture of endothelial and smooth muscle cells for the development of blood vessel constructs
title_full Co-culture of endothelial and smooth muscle cells for the development of blood vessel constructs
title_fullStr Co-culture of endothelial and smooth muscle cells for the development of blood vessel constructs
title_full_unstemmed Co-culture of endothelial and smooth muscle cells for the development of blood vessel constructs
title_short Co-culture of endothelial and smooth muscle cells for the development of blood vessel constructs
title_sort Co-culture of endothelial and smooth muscle cells for the development of blood vessel constructs
topic Engenharia e Tecnologia::Biotecnologia Industrial
topic_facet Engenharia e Tecnologia::Biotecnologia Industrial
url https://hdl.handle.net/1822/59110
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