Publication

Fluid–Structure Interaction Modeling of Ascending Thoracic Aortic Aneurysms in SimVascular

Bibliographic Details
Summary:	Ascending Thoracic Aortic Aneurysm (ATAA) is a permanent dilatation of the aorta which is usually related to tissue degeneration, hemodynamic conditions, lifestyle, environmental and genetic factors. As the mechanical conditions can become critical in a dilated aorta, a patient-specific computational model can be very useful to assist clinical decisions in the management of ATAAs. In this article, we model the biomechanical conditions of ATAA by performing Fluid–Structure Interaction (FSI) simulations in the SimVascular open-source software package. The patient-specific geometric model is reconstructed from Computed Tomography scan (CT). The numerical implementation takes into account patient-specific outlet conditions and a temporal flow variation at the model inlet. We performed a mesh convergence analysis on a new mesh reconstruction method in SimVascular and showed that it can significantly reduce the computational cost without impacting the accuracy.
Main Authors:	Valente, Rodrigo
Other Authors:	Mourato, André; Brito, Moisés; Xavier, José; Tomás, António; Avril, Stéphane
Subject:	ascending thoracic aorta aneurysm (ATAA) fluid–structure interaction (FSI) hemodynamics SimVascular Orthopedics and Sports Medicine Rehabilitation Biomedical Engineering
Year:	2022
Country:	Portugal
Document type:	article
Access type:	open access
Associated institution:	Universidade Nova de Lisboa
Language:	English
Origin:	Repositório Institucional da UNL

Description
Summary:	Ascending Thoracic Aortic Aneurysm (ATAA) is a permanent dilatation of the aorta which is usually related to tissue degeneration, hemodynamic conditions, lifestyle, environmental and genetic factors. As the mechanical conditions can become critical in a dilated aorta, a patient-specific computational model can be very useful to assist clinical decisions in the management of ATAAs. In this article, we model the biomechanical conditions of ATAA by performing Fluid–Structure Interaction (FSI) simulations in the SimVascular open-source software package. The patient-specific geometric model is reconstructed from Computed Tomography scan (CT). The numerical implementation takes into account patient-specific outlet conditions and a temporal flow variation at the model inlet. We performed a mesh convergence analysis on a new mesh reconstruction method in SimVascular and showed that it can significantly reduce the computational cost without impacting the accuracy.