Publicação

Thyroid Function Screening in People Living With Human Immunodeficiency Virus on Antiretroviral Therapy

Ver documento

Detalhes bibliográficos
Resumo:Background People living with human immunodeficiency virus (HIV) may develop endocrine dysfunction, particularly involving the thyroid gland. Although overt thyroid dysfunction in patients living with HIV is similar to that of the general population, subclinical thyroid dysfunction is significantly more prevalent. This study aims to evaluate the prevalence of changes in thyroid function in patients living with HIV on antiretroviral therapy and to determine whether routine thyroid function testing is warranted. Methods Retrospective observational study including 249 people living with HIV on antiretroviral therapy and followed in an Internal Medicine outpatient clinic between 2018 and 2023. Patients with a history of thyroid disease before 2018, those receiving treatment with amiodarone, lithium, interferon, and/or tyrosine kinase inhibitors, and those lacking thyroid function assessment or medical records before 2023 were excluded. Results Of the 249 patients, 96.4% showed no abnormalities in thyroid function. Thyroid dysfunction was identified in nine patients (3.6%): four (1.6%) had subclinical hypothyroidism, one (0.4%) Hashimoto's thyroiditis, two (0.8%) antibody-negative hypothyroidism, and two (0.8%) subclinical hyperthyroidism. Conclusion The overall prevalence of thyroid dysfunction was low, suggesting no benefit in systematic screening of thyroid function among patients living with HIV on antiretroviral therapy.
Autores principais:Bolas, Ana Filipa
Outros Autores:Caixas, Umbelina; Bogalho, Paula; Silva-Nunes, José
Assunto:antiretroviral therapy HIV/AIDS screening thyroid diseases Immunology Dermatology Infectious Diseases SDG 3 - Good Health and Well-being
Ano:2026
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Universidade Nova de Lisboa
Idioma:inglês
Origem:Repositório Institucional da UNL

Registos relacionados

Registos relacionados