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Influenza and COVID-19 vaccination intention in Portuguese adults from at-risk groups

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Resumo:Background: Seasonal influenza and COVID-19 vaccines are critical for protecting at-risk populations, yet uptake remains suboptimal in some priority groups. This study aimed to identify psychosocial and structural factors associated with vaccination intention and hesitancy among Portuguese adults from high-risk groups, including older adults, individuals with chronic conditions, healthcare professionals, and pregnant women. Methods: A mixed-methods design was employed. A cross-sectional telephone survey applied to a probabilistic sample (n = 474) assessed sociodemographic, psychological, and logistical predictors of intention to vaccinate against influenza and COVID-19 among older adults and individuals with chronic illnesses. Semi-structured interviews conducted with vaccine-hesitant healthcare professionals (n = 13) and pregnant women (n = 10) explored perceptions and experiences towards vaccination. Results: Survey findings showed moderately high intentions to vaccinate, with higher scores for influenza than COVID-19. Older age, worry, belief in vaccine safety and efficacy, and healthcare provider recommendations were positively associated with vaccination intention. Conversely, concerns about side effects, preference for natural immunity, and work-related barriers were negatively associated with vaccination intention. Interview data revealed ambivalence toward seasonal vaccines, particularly COVID-19, due to perceived rapid development and limited long-term data. Healthcare professionals often distinguished between seasonal and the national vaccination programme vaccines, mentioning low personal risk and side effects as reasons for hesitancy related to seasonal vaccines. Pregnant women emphasized concerns about fetal safety and the importance of clear healthcare providers recommendations. Conclusions: Psychosocial factors, including beliefs about disease severity and vaccine safety, play a central role in vaccination intention. Work-related structural barriers further contribute to hesitancy. These findings underscore the need for targeted communication strategies, healthcare providers engagement and employer-based vaccination programs to address both structural and motivational aspects of vaccination adherence within priority groups.
Autores principais:Godinho, Cristina A.
Outros Autores:Francisco, Rita; Gaspar, Rui; Henriques, Joana; Costa, Andreia; António, João; Costa, Diana; Fernandes, Teresa; Arriaga, Miguel
Assunto:Chronic illness COVID-19 Healthcare professionals Influenza Mixed-methods Older adults Portugal Pregnant women Vaccine hesitancy Public Health, Environmental and Occupational Health SDG 3 - Good Health and Well-being
Ano:2026
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Universidade Nova de Lisboa
Idioma:inglês
Origem:Repositório Institucional da UNL
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author Godinho, Cristina A.
author2 Francisco, Rita
Gaspar, Rui
Henriques, Joana
Costa, Andreia
António, João
Costa, Diana
Fernandes, Teresa
Arriaga, Miguel
author2_role author
author
author
author
author
author
author
author
author_facet Godinho, Cristina A.
Francisco, Rita
Gaspar, Rui
Henriques, Joana
Costa, Andreia
António, João
Costa, Diana
Fernandes, Teresa
Arriaga, Miguel
author_role author
contributor_name_str_mv Centro de Investigação em Saúde Pública (CISP/PHRC)
Comprehensive Health Research Centre (CHRC) - Pólo ENSP
Escola Nacional de Saúde Pública (ENSP)
BioMed Central (BMC)
RUN
country_str PT
creators_json_txt [{\"Person.name\":\"Godinho, Cristina A.\"},{\"Person.name\":\"Francisco, Rita\"},{\"Person.name\":\"Gaspar, Rui\"},{\"Person.name\":\"Henriques, Joana\"},{\"Person.name\":\"Costa, Andreia\"},{\"Person.name\":\"António, João\"},{\"Person.name\":\"Costa, Diana\"},{\"Person.name\":\"Fernandes, Teresa\"},{\"Person.name\":\"Arriaga, Miguel\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Centro de Investigação em Saúde Pública (CISP/PHRC)
Comprehensive Health Research Centre (CHRC) - Pólo ENSP
Escola Nacional de Saúde Pública (ENSP)
BioMed Central (BMC)
RUN
datacite.creators.creator.creatorName.fl_str_mv Godinho, Cristina A.
Francisco, Rita
Gaspar, Rui
Henriques, Joana
Costa, Andreia
António, João
Costa, Diana
Fernandes, Teresa
Arriaga, Miguel
datacite.date.Accepted.fl_str_mv 2026-12-01T00:00:00Z
datacite.date.available.fl_str_mv 2026-04-15T15:13:02Z
datacite.date.embargoed.fl_str_mv 2026-04-15T15:13:02Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Chronic illness
COVID-19
Healthcare professionals
Influenza
Mixed-methods
Older adults
Portugal
Pregnant women
Vaccine hesitancy
Public Health, Environmental and Occupational Health
SDG 3 - Good Health and Well-being
datacite.titles.title.fl_str_mv Influenza and COVID-19 vaccination intention in Portuguese adults from at-risk groups
a mixed-method study
dc.contributor.none.fl_str_mv Centro de Investigação em Saúde Pública (CISP/PHRC)
Comprehensive Health Research Centre (CHRC) - Pólo ENSP
Escola Nacional de Saúde Pública (ENSP)
BioMed Central (BMC)
RUN
dc.creator.none.fl_str_mv Godinho, Cristina A.
Francisco, Rita
Gaspar, Rui
Henriques, Joana
Costa, Andreia
António, João
Costa, Diana
Fernandes, Teresa
Arriaga, Miguel
dc.date.Accepted.fl_str_mv 2026-12-01T00:00:00Z
dc.date.available.fl_str_mv 2026-04-15T15:13:02Z
dc.date.embargoed.fl_str_mv 2026-04-15T15:13:02Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10362/202260
dc.language.none.fl_str_mv eng
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.subject.none.fl_str_mv Chronic illness
COVID-19
Healthcare professionals
Influenza
Mixed-methods
Older adults
Portugal
Pregnant women
Vaccine hesitancy
Public Health, Environmental and Occupational Health
SDG 3 - Good Health and Well-being
dc.title.fl_str_mv Influenza and COVID-19 vaccination intention in Portuguese adults from at-risk groups
a mixed-method study
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description Background: Seasonal influenza and COVID-19 vaccines are critical for protecting at-risk populations, yet uptake remains suboptimal in some priority groups. This study aimed to identify psychosocial and structural factors associated with vaccination intention and hesitancy among Portuguese adults from high-risk groups, including older adults, individuals with chronic conditions, healthcare professionals, and pregnant women. Methods: A mixed-methods design was employed. A cross-sectional telephone survey applied to a probabilistic sample (n = 474) assessed sociodemographic, psychological, and logistical predictors of intention to vaccinate against influenza and COVID-19 among older adults and individuals with chronic illnesses. Semi-structured interviews conducted with vaccine-hesitant healthcare professionals (n = 13) and pregnant women (n = 10) explored perceptions and experiences towards vaccination. Results: Survey findings showed moderately high intentions to vaccinate, with higher scores for influenza than COVID-19. Older age, worry, belief in vaccine safety and efficacy, and healthcare provider recommendations were positively associated with vaccination intention. Conversely, concerns about side effects, preference for natural immunity, and work-related barriers were negatively associated with vaccination intention. Interview data revealed ambivalence toward seasonal vaccines, particularly COVID-19, due to perceived rapid development and limited long-term data. Healthcare professionals often distinguished between seasonal and the national vaccination programme vaccines, mentioning low personal risk and side effects as reasons for hesitancy related to seasonal vaccines. Pregnant women emphasized concerns about fetal safety and the importance of clear healthcare providers recommendations. Conclusions: Psychosocial factors, including beliefs about disease severity and vaccine safety, play a central role in vaccination intention. Work-related structural barriers further contribute to hesitancy. These findings underscore the need for targeted communication strategies, healthcare providers engagement and employer-based vaccination programs to address both structural and motivational aspects of vaccination adherence within priority groups.
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identifier.url.fl_str_mv http://hdl.handle.net/10362/202260
inst_facet_str urn:organizationAcronym:unl{{{_:::_}}}Universidade Nova de Lisboa
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institution Universidade Nova de Lisboa
instname_str Universidade Nova de Lisboa
language eng
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network_name_str Repositório Institucional da UNL
oai_identifier_str oai:run.unl.pt:10362/202260
organization_str_mv urn:organizationAcronym:unl
person_str_mv Godinho, Cristina A.
Francisco, Rita
Gaspar, Rui
Henriques, Joana
Costa, Andreia
António, João
Costa, Diana
Fernandes, Teresa
Arriaga, Miguel
publishDate 2026
repo_facet_str urn:repositoryAcronym:run{{{_:::_}}}Repositório Institucional da UNL
reponame_str Repositório Institucional da UNL
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spelling engenBackground: Seasonal influenza and COVID-19 vaccines are critical for protecting at-risk populations, yet uptake remains suboptimal in some priority groups. This study aimed to identify psychosocial and structural factors associated with vaccination intention and hesitancy among Portuguese adults from high-risk groups, including older adults, individuals with chronic conditions, healthcare professionals, and pregnant women. Methods: A mixed-methods design was employed. A cross-sectional telephone survey applied to a probabilistic sample (n = 474) assessed sociodemographic, psychological, and logistical predictors of intention to vaccinate against influenza and COVID-19 among older adults and individuals with chronic illnesses. Semi-structured interviews conducted with vaccine-hesitant healthcare professionals (n = 13) and pregnant women (n = 10) explored perceptions and experiences towards vaccination. Results: Survey findings showed moderately high intentions to vaccinate, with higher scores for influenza than COVID-19. Older age, worry, belief in vaccine safety and efficacy, and healthcare provider recommendations were positively associated with vaccination intention. Conversely, concerns about side effects, preference for natural immunity, and work-related barriers were negatively associated with vaccination intention. Interview data revealed ambivalence toward seasonal vaccines, particularly COVID-19, due to perceived rapid development and limited long-term data. Healthcare professionals often distinguished between seasonal and the national vaccination programme vaccines, mentioning low personal risk and side effects as reasons for hesitancy related to seasonal vaccines. Pregnant women emphasized concerns about fetal safety and the importance of clear healthcare providers recommendations. Conclusions: Psychosocial factors, including beliefs about disease severity and vaccine safety, play a central role in vaccination intention. Work-related structural barriers further contribute to hesitancy. These findings underscore the need for targeted communication strategies, healthcare providers engagement and employer-based vaccination programs to address both structural and motivational aspects of vaccination adherence within priority groups.application/pdfenInfluenza and COVID-19 vaccination intention in Portuguese adults from at-risk groupsSubtitleena mixed-method studyGodinho, Cristina A.Francisco, RitaGaspar, RuiHenriques, JoanaCosta, AndreiaAntónio, JoãoCosta, DianaFernandes, TeresaArriaga, MiguelCentro de Investigação em Saúde Pública (CISP/PHRC)Comprehensive Health Research Centre (CHRC) - Pólo ENSPEscola Nacional de Saúde Pública (ENSP)BioMed Central (BMC)HostingInstitutionOrganizationalRUNe-mailmailto:run@unl.ptrun@unl.ptISSNIsPartOf1471-2458URNIsPartOfPURE: 160531217URNIsPartOfPURE UUID: 9f996733-a31e-4e2d-99cb-582f00421817URNIsPartOfScopus: 105028963177URNIsPartOfPubMed: 41455959URNIsPartOfPubMedCentral: PMC12859839URNIsPartOfWOS: 001676665500001DOIIsPartOf10.1186/s12889-025-25591-y2026-04-15T15:13:02Z2026-122026-12-01T00:00:00ZHandlehttp://hdl.handle.net/10362/202260http://purl.org/coar/access_right/c_abf2open accessChronic illnessCOVID-19Healthcare professionalsInfluenzaMixed-methodsOlder adultsPortugalPregnant womenVaccine hesitancyPublic Health, Environmental and Occupational HealthSDG 3 - Good Health and Well-being1763727 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://run.unl.pt/bitstreams/53a94df3-bfc4-4383-986f-b980a7e78186/download
spellingShingle Influenza and COVID-19 vaccination intention in Portuguese adults from at-risk groups
Godinho, Cristina A.
Chronic illness
COVID-19
Healthcare professionals
Influenza
Mixed-methods
Older adults
Portugal
Pregnant women
Vaccine hesitancy
Public Health, Environmental and Occupational Health
SDG 3 - Good Health and Well-being
status SINGLETON
subject.fl_str_mv Chronic illness
COVID-19
Healthcare professionals
Influenza
Mixed-methods
Older adults
Portugal
Pregnant women
Vaccine hesitancy
Public Health, Environmental and Occupational Health
SDG 3 - Good Health and Well-being
title Influenza and COVID-19 vaccination intention in Portuguese adults from at-risk groups
title_full Influenza and COVID-19 vaccination intention in Portuguese adults from at-risk groups
title_fullStr Influenza and COVID-19 vaccination intention in Portuguese adults from at-risk groups
title_full_unstemmed Influenza and COVID-19 vaccination intention in Portuguese adults from at-risk groups
title_short Influenza and COVID-19 vaccination intention in Portuguese adults from at-risk groups
title_sort Influenza and COVID-19 vaccination intention in Portuguese adults from at-risk groups
topic Chronic illness
COVID-19
Healthcare professionals
Influenza
Mixed-methods
Older adults
Portugal
Pregnant women
Vaccine hesitancy
Public Health, Environmental and Occupational Health
SDG 3 - Good Health and Well-being
topic_facet Chronic illness
COVID-19
Healthcare professionals
Influenza
Mixed-methods
Older adults
Portugal
Pregnant women
Vaccine hesitancy
Public Health, Environmental and Occupational Health
SDG 3 - Good Health and Well-being
url http://hdl.handle.net/10362/202260
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