Publication

Extraction of bioactive compounds from Cannabis sativa L. flowers and/or leaves using deep eutectic solvents

View document

Bibliographic Details
Summary:The increasing demand for medical cannabis urges the development for new and effective methods for the extraction of phytocannabinoids. Deep eutectic Solvents (DESs) are an alternative to the use of hazardous organic solvents typically used in the industry. In this study, DESs were developed, based on terpenes, sugars, and natural organic acids, as a green extraction media for the extraction of cannabis bioactive compounds. The factors influencing the extraction of bioactive components, such as the type of DESs and extraction time were investigated. Initial screening in hemp showed that the DES composed of Menthol: Lauric acid (2:1 M ratio) had a greater extraction efficiency of CBD and CBDA (11,07 ± 0,37 mg/g) of all the tested DESs and higher than ethanol. In medical cannabis Men:Lac (2:1 M ratio) allowed an extraction as effective as ethanol. Besides having a higher or equivalent extraction yield as the organic solvents tested, DESs showed to be more selective extracting less impurities, such as chlorophyll and waxes. These results coupled with the non-toxic, biodegradable, low cost and environmentally friendly characteristics of DESs, provided strong evidence that DESs represents a better alternative to organic solvents.
Main Authors:Tiago, Francisco José Martins
Subject:Cannabis sativa Green Extraction Deep Eutectic Solvents Cannabinoids
Year:2022
Country:Portugal
Document type:master thesis
Access type:open access
Associated institution:Universidade Nova de Lisboa
Language:English
Origin:Repositório Institucional da UNL

Similar Items

Similar Items