Publicação

Chemical synthesis of new histone deacetylase inhibitors and their evaluation as anticancer agents

Detalhes bibliográficos
Resumo:	"Epigenetics and its key role in gene expression have become increasingly important in cancer research. Histone proteins play an important role in gene expression control through modifications like acetylation, phosphorylation and methylation. Histone deacetylases (HDAC) can regulate expression levels via acetylation of lysine residues of histone proteins.(...)"
Autores principais:	Diana O. Silva
Assunto:	HDACi Chemical Synthesis
Ano:	2016
País:	Portugal
Tipo de documento:	dissertação de mestrado
Tipo de acesso:	acesso aberto
Instituição associada:	Universidade Nova de Lisboa
Idioma:	inglês
Origem:	Repositório Institucional da UNL

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