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The estimated distribution of autochthonous leishmaniasis by Leishmania infantum in Europe in 2005–2020

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Resumo:Background This study describes the spatial and temporal distribution between 2005 and 2020 of human and animal leishmaniasis by Leishmania infantum in European countries reporting autoch-thonous cases, and highlights potential activities to improve disease control. Methodology/Principal findings It was based on a review of the scientific literature and data reported by the World Health Organization (WHO), the World Organization for Animal Health (WOAH) and the Ministries of Health, including hospital discharges in some countries. Autochthonous infections were reported in the scientific literature from 22 countries, including 13 and 21 countries reporting human and animal infections, respectively. In contrast, only 17 countries reported autoch-thonous human leishmaniasis cases to the WHO and 8 countries animal infections to the WOAH. The number of WOAH reported cases were 4,203, comprising 4,183 canine cases and 20 cases in wildlife. Of 8,367 WHO reported human cases, 69% were visceral leishman-iasis cases—of which 94% were autochthonous—and 31% cutaneous leishmaniasis cases —of which 53% were imported and mostly in France. The resulting cumulative incidence per 100,000 population of visceral leishmaniasis between 2005–2020, was highest in Albania (2.15 cases), followed by Montenegro, Malta, Greece, Spain and North Macedonia (0.53– 0.42), Italy (0.16), Portugal (0.09) and lower in other endemic countries (0.07–0.002). However, according to hospital discharges, the estimated human leishmaniasis incidence was 0.70 in Italy and visceral leishmaniasis incidences were 0.67 in Spain and 0.41 in Portugal. Conclusions/Significance Overall, there was no evidence of widespread increased incidence of autochthonous human leishmaniasis by L. infantum in European countries. Visceral leishmaniasis incidence followed a decreasing trend in Albania, Italy and Portugal, and peaked in Greece in 2013, 2014 and 2017, and in Spain in 2006–2007 and 2011–2013. Animal and human cutaneous leishmaniasis remain highly underreported. In humans, hospital discharge databases pro-vide the most accurate information on visceral leishmaniasis and may be a valuable indirect source of information to identify hotspots of animal leishmaniasis. Integrated leishmaniasis surveillance and reporting following the One Health approach, needs to be enhanced in order to improve disease control.
Autores principais:Maia, Carla
Outros Autores:Conceição, Cláudia; Pereira, André; Rocha, Rafael; Ortuño, Maria; Muñozid, Clara; Jumakanova, Zarima; Pérez-Cutillas, Pedro; Özbel, Yusuf; Töz, Seray; Baneth, Gad; Monge-Maillo, Begoña; Gasimov, Elkhan; Van der Stede, Yves; Torres, Gregorio; Gossner, Céline M.; Berriatua, Eduardo
Assunto:Leishmania infantum autochthounous leishmaniasis Europe RA0421 Public health. Hygiene. Preventive Medicine Public Health, Environmental and Occupational Health Infectious Diseases Epidemiology Parasitology General Veterinary SDG 3 - Good Health and Well-being
Ano:2023
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Universidade Nova de Lisboa
Idioma:inglês
Origem:Repositório Institucional da UNL
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author Maia, Carla
author2 Conceição, Cláudia
Pereira, André
Rocha, Rafael
Ortuño, Maria
Muñozid, Clara
Jumakanova, Zarima
Pérez-Cutillas, Pedro
Özbel, Yusuf
Töz, Seray
Baneth, Gad
Monge-Maillo, Begoña
Gasimov, Elkhan
Van der Stede, Yves
Torres, Gregorio
Gossner, Céline M.
Berriatua, Eduardo
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author_facet Maia, Carla
Conceição, Cláudia
Pereira, André
Rocha, Rafael
Ortuño, Maria
Muñozid, Clara
Jumakanova, Zarima
Pérez-Cutillas, Pedro
Özbel, Yusuf
Töz, Seray
Baneth, Gad
Monge-Maillo, Begoña
Gasimov, Elkhan
Van der Stede, Yves
Torres, Gregorio
Gossner, Céline M.
Berriatua, Eduardo
author_role author
contributor_name_str_mv Vector borne diseases and pathogens (VBD)
Instituto de Higiene e Medicina Tropical (IHMT)
Global Health and Tropical Medicine (GHTM)
Individual Health Care (IHC)
PLOS - Public Library of Science
RUN
country_str PT
creators_json_txt [{\"Person.name\":\"Maia, Carla\"},{\"Person.name\":\"Conceição, Cláudia\"},{\"Person.name\":\"Pereira, André\"},{\"Person.name\":\"Rocha, Rafael\"},{\"Person.name\":\"Ortuño, Maria\"},{\"Person.name\":\"Muñozid, Clara\"},{\"Person.name\":\"Jumakanova, Zarima\"},{\"Person.name\":\"Pérez-Cutillas, Pedro\"},{\"Person.name\":\"Özbel, Yusuf\"},{\"Person.name\":\"Töz, Seray\"},{\"Person.name\":\"Baneth, Gad\"},{\"Person.name\":\"Monge-Maillo, Begoña\"},{\"Person.name\":\"Gasimov, Elkhan\"},{\"Person.name\":\"Van der Stede, Yves\"},{\"Person.name\":\"Torres, Gregorio\"},{\"Person.name\":\"Gossner, Céline M.\"},{\"Person.name\":\"Berriatua, Eduardo\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Vector borne diseases and pathogens (VBD)
Instituto de Higiene e Medicina Tropical (IHMT)
Global Health and Tropical Medicine (GHTM)
Individual Health Care (IHC)
PLOS - Public Library of Science
RUN
datacite.creators.creator.creatorName.fl_str_mv Maia, Carla
Conceição, Cláudia
Pereira, André
Rocha, Rafael
Ortuño, Maria
Muñozid, Clara
Jumakanova, Zarima
Pérez-Cutillas, Pedro
Özbel, Yusuf
Töz, Seray
Baneth, Gad
Monge-Maillo, Begoña
Gasimov, Elkhan
Van der Stede, Yves
Torres, Gregorio
Gossner, Céline M.
Berriatua, Eduardo
datacite.date.Accepted.fl_str_mv 2023-07-01T00:00:00Z
datacite.date.available.fl_str_mv 2023-09-01T22:16:08Z
datacite.date.embargoed.fl_str_mv 2023-09-01T22:16:08Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Leishmania infantum
autochthounous leishmaniasis
Europe
RA0421 Public health. Hygiene. Preventive Medicine
Public Health, Environmental and Occupational Health
Infectious Diseases
Epidemiology
Parasitology
General Veterinary
SDG 3 - Good Health and Well-being
datacite.titles.title.fl_str_mv The estimated distribution of autochthonous leishmaniasis by Leishmania infantum in Europe in 2005–2020
dc.contributor.none.fl_str_mv Vector borne diseases and pathogens (VBD)
Instituto de Higiene e Medicina Tropical (IHMT)
Global Health and Tropical Medicine (GHTM)
Individual Health Care (IHC)
PLOS - Public Library of Science
RUN
dc.creator.none.fl_str_mv Maia, Carla
Conceição, Cláudia
Pereira, André
Rocha, Rafael
Ortuño, Maria
Muñozid, Clara
Jumakanova, Zarima
Pérez-Cutillas, Pedro
Özbel, Yusuf
Töz, Seray
Baneth, Gad
Monge-Maillo, Begoña
Gasimov, Elkhan
Van der Stede, Yves
Torres, Gregorio
Gossner, Céline M.
Berriatua, Eduardo
dc.date.Accepted.fl_str_mv 2023-07-01T00:00:00Z
dc.date.available.fl_str_mv 2023-09-01T22:16:08Z
dc.date.embargoed.fl_str_mv 2023-09-01T22:16:08Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10362/157228
dc.language.none.fl_str_mv eng
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.subject.none.fl_str_mv Leishmania infantum
autochthounous leishmaniasis
Europe
RA0421 Public health. Hygiene. Preventive Medicine
Public Health, Environmental and Occupational Health
Infectious Diseases
Epidemiology
Parasitology
General Veterinary
SDG 3 - Good Health and Well-being
dc.title.fl_str_mv The estimated distribution of autochthonous leishmaniasis by Leishmania infantum in Europe in 2005–2020
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description Background This study describes the spatial and temporal distribution between 2005 and 2020 of human and animal leishmaniasis by Leishmania infantum in European countries reporting autoch-thonous cases, and highlights potential activities to improve disease control. Methodology/Principal findings It was based on a review of the scientific literature and data reported by the World Health Organization (WHO), the World Organization for Animal Health (WOAH) and the Ministries of Health, including hospital discharges in some countries. Autochthonous infections were reported in the scientific literature from 22 countries, including 13 and 21 countries reporting human and animal infections, respectively. In contrast, only 17 countries reported autoch-thonous human leishmaniasis cases to the WHO and 8 countries animal infections to the WOAH. The number of WOAH reported cases were 4,203, comprising 4,183 canine cases and 20 cases in wildlife. Of 8,367 WHO reported human cases, 69% were visceral leishman-iasis cases—of which 94% were autochthonous—and 31% cutaneous leishmaniasis cases —of which 53% were imported and mostly in France. The resulting cumulative incidence per 100,000 population of visceral leishmaniasis between 2005–2020, was highest in Albania (2.15 cases), followed by Montenegro, Malta, Greece, Spain and North Macedonia (0.53– 0.42), Italy (0.16), Portugal (0.09) and lower in other endemic countries (0.07–0.002). However, according to hospital discharges, the estimated human leishmaniasis incidence was 0.70 in Italy and visceral leishmaniasis incidences were 0.67 in Spain and 0.41 in Portugal. Conclusions/Significance Overall, there was no evidence of widespread increased incidence of autochthonous human leishmaniasis by L. infantum in European countries. Visceral leishmaniasis incidence followed a decreasing trend in Albania, Italy and Portugal, and peaked in Greece in 2013, 2014 and 2017, and in Spain in 2006–2007 and 2011–2013. Animal and human cutaneous leishmaniasis remain highly underreported. In humans, hospital discharge databases pro-vide the most accurate information on visceral leishmaniasis and may be a valuable indirect source of information to identify hotspots of animal leishmaniasis. Integrated leishmaniasis surveillance and reporting following the One Health approach, needs to be enhanced in order to improve disease control.
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organization_str_mv urn:organizationAcronym:unl
person_str_mv Maia, Carla
Conceição, Cláudia
Pereira, André
Rocha, Rafael
Ortuño, Maria
Muñozid, Clara
Jumakanova, Zarima
Pérez-Cutillas, Pedro
Özbel, Yusuf
Töz, Seray
Baneth, Gad
Monge-Maillo, Begoña
Gasimov, Elkhan
Van der Stede, Yves
Torres, Gregorio
Gossner, Céline M.
Berriatua, Eduardo
publishDate 2023
repo_facet_str urn:repositoryAcronym:run{{{_:::_}}}Repositório Institucional da UNL
reponame_str Repositório Institucional da UNL
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spelling engenBackground This study describes the spatial and temporal distribution between 2005 and 2020 of human and animal leishmaniasis by Leishmania infantum in European countries reporting autoch-thonous cases, and highlights potential activities to improve disease control. Methodology/Principal findings It was based on a review of the scientific literature and data reported by the World Health Organization (WHO), the World Organization for Animal Health (WOAH) and the Ministries of Health, including hospital discharges in some countries. Autochthonous infections were reported in the scientific literature from 22 countries, including 13 and 21 countries reporting human and animal infections, respectively. In contrast, only 17 countries reported autoch-thonous human leishmaniasis cases to the WHO and 8 countries animal infections to the WOAH. The number of WOAH reported cases were 4,203, comprising 4,183 canine cases and 20 cases in wildlife. Of 8,367 WHO reported human cases, 69% were visceral leishman-iasis cases—of which 94% were autochthonous—and 31% cutaneous leishmaniasis cases —of which 53% were imported and mostly in France. The resulting cumulative incidence per 100,000 population of visceral leishmaniasis between 2005–2020, was highest in Albania (2.15 cases), followed by Montenegro, Malta, Greece, Spain and North Macedonia (0.53– 0.42), Italy (0.16), Portugal (0.09) and lower in other endemic countries (0.07–0.002). However, according to hospital discharges, the estimated human leishmaniasis incidence was 0.70 in Italy and visceral leishmaniasis incidences were 0.67 in Spain and 0.41 in Portugal. Conclusions/Significance Overall, there was no evidence of widespread increased incidence of autochthonous human leishmaniasis by L. infantum in European countries. Visceral leishmaniasis incidence followed a decreasing trend in Albania, Italy and Portugal, and peaked in Greece in 2013, 2014 and 2017, and in Spain in 2006–2007 and 2011–2013. Animal and human cutaneous leishmaniasis remain highly underreported. In humans, hospital discharge databases pro-vide the most accurate information on visceral leishmaniasis and may be a valuable indirect source of information to identify hotspots of animal leishmaniasis. Integrated leishmaniasis surveillance and reporting following the One Health approach, needs to be enhanced in order to improve disease control.application/pdfenThe estimated distribution of autochthonous leishmaniasis by Leishmania infantum in Europe in 2005–2020Maia, CarlaConceição, CláudiaPereira, AndréRocha, RafaelOrtuño, MariaMuñozid, ClaraJumakanova, ZarimaPérez-Cutillas, PedroÖzbel, YusufTöz, SerayBaneth, GadMonge-Maillo, BegoñaGasimov, ElkhanVan der Stede, YvesTorres, GregorioGossner, Céline M.Berriatua, EduardoVector borne diseases and pathogens (VBD)Instituto de Higiene e Medicina Tropical (IHMT)Global Health and Tropical Medicine (GHTM)Individual Health Care (IHC)PLOS - Public Library of ScienceHostingInstitutionOrganizationalRUNe-mailmailto:run@unl.ptrun@unl.ptISSNIsPartOf1935-2727URNIsPartOfPURE: 70471846URNIsPartOfPURE UUID: e6d116a6-18a2-4334-9d87-a1c100b66ac3URNIsPartOfScopus: 85166341285URNIsPartOfWOS: WOS:001034802100003URNIsPartOfPubMed: 37467280URNIsPartOfPubMedCentral: PMC10389729URNIsPartOfORCID: /0000-0001-7004-0268/work/151417239URNIsPartOfORCID: /0000-0002-2545-7686/work/151418960DOIIsPartOf10.1371/journal.pntd.00114972023-09-01T22:16:08Z2023-072023-07-01T00:00:00ZHandlehttp://hdl.handle.net/10362/157228http://purl.org/coar/access_right/c_abf2open accessLeishmania infantumautochthounous leishmaniasisEuropeRA0421 Public health. Hygiene. Preventive MedicinePublic Health, Environmental and Occupational HealthInfectious DiseasesEpidemiologyParasitologyGeneral VeterinarySDG 3 - Good Health and Well-being2490909 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://run.unl.pt/bitstreams/5223f45e-2a2c-41a6-9138-7d86b26fecd1/download
spellingShingle The estimated distribution of autochthonous leishmaniasis by Leishmania infantum in Europe in 2005–2020
Maia, Carla
Leishmania infantum
autochthounous leishmaniasis
Europe
RA0421 Public health. Hygiene. Preventive Medicine
Public Health, Environmental and Occupational Health
Infectious Diseases
Epidemiology
Parasitology
General Veterinary
SDG 3 - Good Health and Well-being
status SINGLETON
subject.fl_str_mv Leishmania infantum
autochthounous leishmaniasis
Europe
RA0421 Public health. Hygiene. Preventive Medicine
Public Health, Environmental and Occupational Health
Infectious Diseases
Epidemiology
Parasitology
General Veterinary
SDG 3 - Good Health and Well-being
title The estimated distribution of autochthonous leishmaniasis by Leishmania infantum in Europe in 2005–2020
title_full The estimated distribution of autochthonous leishmaniasis by Leishmania infantum in Europe in 2005–2020
title_fullStr The estimated distribution of autochthonous leishmaniasis by Leishmania infantum in Europe in 2005–2020
title_full_unstemmed The estimated distribution of autochthonous leishmaniasis by Leishmania infantum in Europe in 2005–2020
title_short The estimated distribution of autochthonous leishmaniasis by Leishmania infantum in Europe in 2005–2020
title_sort The estimated distribution of autochthonous leishmaniasis by Leishmania infantum in Europe in 2005–2020
topic Leishmania infantum
autochthounous leishmaniasis
Europe
RA0421 Public health. Hygiene. Preventive Medicine
Public Health, Environmental and Occupational Health
Infectious Diseases
Epidemiology
Parasitology
General Veterinary
SDG 3 - Good Health and Well-being
topic_facet Leishmania infantum
autochthounous leishmaniasis
Europe
RA0421 Public health. Hygiene. Preventive Medicine
Public Health, Environmental and Occupational Health
Infectious Diseases
Epidemiology
Parasitology
General Veterinary
SDG 3 - Good Health and Well-being
url http://hdl.handle.net/10362/157228
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