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Deep Learning in COVID-19 lung ultrasound analysis

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Resumo:One of the determining factors for the COVID-19 course of treatment is disease severity. Medical imaging, particularly CT scans and X-rays, is frequently used in this assessment. However, these methods have significant downsides. Lung ultrasound has recently gained recognition as an alternative to CT scans and X-rays due to the advantages presented by the exam. Lung ultrasounds are cost-effective, portable, fast, non-invasive, easily repeat- able, and do not expose patients to radiation. These aspects are particularly relevant in the context of low-resource health care providers. This study proposes a framework for automated severity analysis of COVID-19 lung ultrasounds, intended to detect frames presenting alterations indicative of the disease and provide its subsequent severity classification. The system could be used to ease the learning process of health care providers and enable them to obtain expert-level COVID- 19 severity assessments even in low-resource situations. The pipeline is comprised of two main modules, the frame selection phase, and a frame classification phase. Due to dataset limitations, the demonstration of the entire se- quence of the pipeline is unachievable. Thus, both phases of the project were approached separately. The frame selection phase consisted of unsupervised learning methods and thus couldn’t be evaluated in this study’s context. Instead, the study offers a demonstration of this step’s procedures. As for the frame classification phase, the study optimized four CNN architectures, one for each anomaly considered for severity classification. All four models were able to accurately determine severity. Based on these findings, the study concluded that by having pre-selected informative frames, it’s possible to train a classifier to reproduce the doctor-attributed scores, which suggests the feasibility of the proposed pipeline.
Autores principais:Cerqueira, Marta de Oliveira
Assunto:COVID-19 SARS-CoV-2 Lung ultrasound Dimensionality Reduction Clustering Convolutional Neural Network (CNN)
Ano:2022
País:Portugal
Tipo de documento:dissertação de mestrado
Tipo de acesso:acesso aberto
Instituição associada:Universidade Nova de Lisboa
Idioma:inglês
Origem:Repositório Institucional da UNL
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author Cerqueira, Marta de Oliveira
author_facet Cerqueira, Marta de Oliveira
author_role author
contributor_name_str_mv Krippahl, Ludwig
Bispo, Regina
RUN
country_str PT
creators_json_txt [{\"Person.name\":\"Cerqueira, Marta de Oliveira\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Krippahl, Ludwig
Bispo, Regina
RUN
datacite.creators.creator.creatorName.fl_str_mv Cerqueira, Marta de Oliveira
datacite.date.Accepted.fl_str_mv 2022-12-01T00:00:00Z
datacite.date.available.fl_str_mv 2024-05-14T14:11:04Z
datacite.date.embargoed.fl_str_mv 2024-05-14T14:11:04Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv COVID-19
SARS-CoV-2
Lung ultrasound
Dimensionality Reduction
Clustering
Convolutional Neural Network (CNN)
datacite.titles.title.fl_str_mv Deep Learning in COVID-19 lung ultrasound analysis
dc.contributor.none.fl_str_mv Krippahl, Ludwig
Bispo, Regina
RUN
dc.creator.none.fl_str_mv Cerqueira, Marta de Oliveira
dc.date.Accepted.fl_str_mv 2022-12-01T00:00:00Z
dc.date.available.fl_str_mv 2024-05-14T14:11:04Z
dc.date.embargoed.fl_str_mv 2024-05-14T14:11:04Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10362/167374
dc.language.none.fl_str_mv eng
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.subject.none.fl_str_mv COVID-19
SARS-CoV-2
Lung ultrasound
Dimensionality Reduction
Clustering
Convolutional Neural Network (CNN)
dc.title.fl_str_mv Deep Learning in COVID-19 lung ultrasound analysis
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_bdcc
description One of the determining factors for the COVID-19 course of treatment is disease severity. Medical imaging, particularly CT scans and X-rays, is frequently used in this assessment. However, these methods have significant downsides. Lung ultrasound has recently gained recognition as an alternative to CT scans and X-rays due to the advantages presented by the exam. Lung ultrasounds are cost-effective, portable, fast, non-invasive, easily repeat- able, and do not expose patients to radiation. These aspects are particularly relevant in the context of low-resource health care providers. This study proposes a framework for automated severity analysis of COVID-19 lung ultrasounds, intended to detect frames presenting alterations indicative of the disease and provide its subsequent severity classification. The system could be used to ease the learning process of health care providers and enable them to obtain expert-level COVID- 19 severity assessments even in low-resource situations. The pipeline is comprised of two main modules, the frame selection phase, and a frame classification phase. Due to dataset limitations, the demonstration of the entire se- quence of the pipeline is unachievable. Thus, both phases of the project were approached separately. The frame selection phase consisted of unsupervised learning methods and thus couldn’t be evaluated in this study’s context. Instead, the study offers a demonstration of this step’s procedures. As for the frame classification phase, the study optimized four CNN architectures, one for each anomaly considered for severity classification. All four models were able to accurately determine severity. Based on these findings, the study concluded that by having pre-selected informative frames, it’s possible to train a classifier to reproduce the doctor-attributed scores, which suggests the feasibility of the proposed pipeline.
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person_str_mv Cerqueira, Marta de Oliveira
publishDate 2022
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spelling engpt_PTOne of the determining factors for the COVID-19 course of treatment is disease severity. Medical imaging, particularly CT scans and X-rays, is frequently used in this assessment. However, these methods have significant downsides. Lung ultrasound has recently gained recognition as an alternative to CT scans and X-rays due to the advantages presented by the exam. Lung ultrasounds are cost-effective, portable, fast, non-invasive, easily repeat- able, and do not expose patients to radiation. These aspects are particularly relevant in the context of low-resource health care providers. This study proposes a framework for automated severity analysis of COVID-19 lung ultrasounds, intended to detect frames presenting alterations indicative of the disease and provide its subsequent severity classification. The system could be used to ease the learning process of health care providers and enable them to obtain expert-level COVID- 19 severity assessments even in low-resource situations. The pipeline is comprised of two main modules, the frame selection phase, and a frame classification phase. Due to dataset limitations, the demonstration of the entire se- quence of the pipeline is unachievable. Thus, both phases of the project were approached separately. The frame selection phase consisted of unsupervised learning methods and thus couldn’t be evaluated in this study’s context. Instead, the study offers a demonstration of this step’s procedures. As for the frame classification phase, the study optimized four CNN architectures, one for each anomaly considered for severity classification. All four models were able to accurately determine severity. Based on these findings, the study concluded that by having pre-selected informative frames, it’s possible to train a classifier to reproduce the doctor-attributed scores, which suggests the feasibility of the proposed pipeline.application/pdfpt_PTDeep Learning in COVID-19 lung ultrasound analysisCerqueira, Marta de OliveiraKrippahl, LudwigBispo, ReginaHostingInstitutionOrganizationalRUNe-mailmailto:run@unl.ptrun@unl.pt2024-05-14T14:11:04Z2022-122022-12-01T00:00:00ZHandlehttp://hdl.handle.net/10362/167374http://purl.org/coar/access_right/c_abf2open accessCOVID-19SARS-CoV-2Lung ultrasoundDimensionality ReductionClusteringConvolutional Neural Network (CNN)7350545 bytesliteraturehttp://purl.org/coar/resource_type/c_bdccmaster thesishttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://run.unl.pt/bitstreams/26947897-eb1c-47ed-8714-8772979c6c97/download
spellingShingle Deep Learning in COVID-19 lung ultrasound analysis
Cerqueira, Marta de Oliveira
COVID-19
SARS-CoV-2
Lung ultrasound
Dimensionality Reduction
Clustering
Convolutional Neural Network (CNN)
status SINGLETON
subject.fl_str_mv COVID-19
SARS-CoV-2
Lung ultrasound
Dimensionality Reduction
Clustering
Convolutional Neural Network (CNN)
title Deep Learning in COVID-19 lung ultrasound analysis
title_full Deep Learning in COVID-19 lung ultrasound analysis
title_fullStr Deep Learning in COVID-19 lung ultrasound analysis
title_full_unstemmed Deep Learning in COVID-19 lung ultrasound analysis
title_short Deep Learning in COVID-19 lung ultrasound analysis
title_sort Deep Learning in COVID-19 lung ultrasound analysis
topic COVID-19
SARS-CoV-2
Lung ultrasound
Dimensionality Reduction
Clustering
Convolutional Neural Network (CNN)
topic_facet COVID-19
SARS-CoV-2
Lung ultrasound
Dimensionality Reduction
Clustering
Convolutional Neural Network (CNN)
url http://hdl.handle.net/10362/167374
visible 1