Publicação
Effects of Physical Activity and Nutrition Education on the Gut Microbiota in Overweight and Obese Children
| Resumo: | Childhood obesity continues to represent a growing challenge, and it has been associated with gut microbiota dysbiosis. This study examines the gut microbiota composition in overweight and obese school children and assesses whether a 12-week multidisciplinary intervention can induce changes in the gut microbiota. The intervention, which combined recreational football and nutritional education, was implemented among 15 school children, aged 7–10 years, with a Body Mass Index ≥ 85th percentile. The children were assigned into two groups: Football Group (n = 9) and Nutrition and Football Group (n = 6). Faecal samples were collected at the beginning and end of the program and analysed by sequencing the 16S rRNA gene. Over the intervention, a significant decrease was found collectively for Bifidobacterium genera (p = 0.011) and for Roseburia genera in the Football Group (p = 0.021). The relative abundance of Roseburia (p = 0.002) and Roseburia faecis (p = 0.009) was negatively correlated with moderate to vigorous physical activity (MVPA), while Prevotella copri was positively correlated with MVPA (p = 0.010) and with the daily intake of protein (p = 0.008). Our findings suggest that a multidisciplinary intervention was capable of inducing limited but significant positive changes in the gut microbiota composition in overweight and obese school children. |
|---|---|
| Autores principais: | Morgado, Micaela C. |
| Outros Autores: | Sousa, Mónica; Marques, Cláudia; Coelho, André B.; Costa, Júlio A.; Seabra, André |
| Assunto: | Bifidobacterium childhood obesity Firmicutes-to-Bacteroidetes ratio football gut microbiota nutrition physical activity Prevotella Pediatrics, Perinatology, and Child Health SDG 3 - Good Health and Well-being |
| Ano: | 2023 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade Nova de Lisboa |
| Idioma: | inglês |
| Origem: | Repositório Institucional da UNL |
| _version_ | 1868983327263817728 |
|---|---|
| author | Morgado, Micaela C. |
| author2 | Sousa, Mónica Marques, Cláudia Coelho, André B. Costa, Júlio A. Seabra, André |
| author2_role | author author author author author |
| author_facet | Morgado, Micaela C. Sousa, Mónica Marques, Cláudia Coelho, André B. Costa, Júlio A. Seabra, André |
| author_role | author |
| contributor_name_str_mv | NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM) Centro de Investigação em Tecnologias e Serviços de Saúde (CINTESIS) MDPI - Multidisciplinary Digital Publishing Institute RUN |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Morgado, Micaela C.\"},{\"Person.name\":\"Sousa, Mónica\"},{\"Person.name\":\"Marques, Cláudia\"},{\"Person.name\":\"Coelho, André B.\"},{\"Person.name\":\"Costa, Júlio A.\"},{\"Person.name\":\"Seabra, André\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM) Centro de Investigação em Tecnologias e Serviços de Saúde (CINTESIS) MDPI - Multidisciplinary Digital Publishing Institute RUN |
| datacite.creators.creator.creatorName.fl_str_mv | Morgado, Micaela C. Sousa, Mónica Marques, Cláudia Coelho, André B. Costa, Júlio A. Seabra, André |
| datacite.date.Accepted.fl_str_mv | 2023-07-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2023-09-25T22:19:58Z |
| datacite.date.embargoed.fl_str_mv | 2023-09-25T22:19:58Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Bifidobacterium childhood obesity Firmicutes-to-Bacteroidetes ratio football gut microbiota nutrition physical activity Prevotella Pediatrics, Perinatology, and Child Health SDG 3 - Good Health and Well-being |
| datacite.titles.title.fl_str_mv | Effects of Physical Activity and Nutrition Education on the Gut Microbiota in Overweight and Obese Children |
| dc.contributor.none.fl_str_mv | NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM) Centro de Investigação em Tecnologias e Serviços de Saúde (CINTESIS) MDPI - Multidisciplinary Digital Publishing Institute RUN |
| dc.creator.none.fl_str_mv | Morgado, Micaela C. Sousa, Mónica Marques, Cláudia Coelho, André B. Costa, Júlio A. Seabra, André |
| dc.date.Accepted.fl_str_mv | 2023-07-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2023-09-25T22:19:58Z |
| dc.date.embargoed.fl_str_mv | 2023-09-25T22:19:58Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | http://hdl.handle.net/10362/158269 |
| dc.language.none.fl_str_mv | eng |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | Bifidobacterium childhood obesity Firmicutes-to-Bacteroidetes ratio football gut microbiota nutrition physical activity Prevotella Pediatrics, Perinatology, and Child Health SDG 3 - Good Health and Well-being |
| dc.title.fl_str_mv | Effects of Physical Activity and Nutrition Education on the Gut Microbiota in Overweight and Obese Children |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Childhood obesity continues to represent a growing challenge, and it has been associated with gut microbiota dysbiosis. This study examines the gut microbiota composition in overweight and obese school children and assesses whether a 12-week multidisciplinary intervention can induce changes in the gut microbiota. The intervention, which combined recreational football and nutritional education, was implemented among 15 school children, aged 7–10 years, with a Body Mass Index ≥ 85th percentile. The children were assigned into two groups: Football Group (n = 9) and Nutrition and Football Group (n = 6). Faecal samples were collected at the beginning and end of the program and analysed by sequencing the 16S rRNA gene. Over the intervention, a significant decrease was found collectively for Bifidobacterium genera (p = 0.011) and for Roseburia genera in the Football Group (p = 0.021). The relative abundance of Roseburia (p = 0.002) and Roseburia faecis (p = 0.009) was negatively correlated with moderate to vigorous physical activity (MVPA), while Prevotella copri was positively correlated with MVPA (p = 0.010) and with the daily intake of protein (p = 0.008). Our findings suggest that a multidisciplinary intervention was capable of inducing limited but significant positive changes in the gut microbiota composition in overweight and obese school children. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| fulltext.url.fl_str_mv | https://run.unl.pt/bitstreams/7a1c98d5-3452-4961-ac71-38aaded86c98/download |
| id | run_90cd2a12f0e1b2a55befb4081aabfc8e |
| identifier.url.fl_str_mv | http://hdl.handle.net/10362/158269 |
| inst_facet_str | urn:organizationAcronym:unl{{{_:::_}}}Universidade Nova de Lisboa |
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| institution | Universidade Nova de Lisboa |
| instname_str | Universidade Nova de Lisboa |
| language | eng |
| network_acronym_str | run |
| network_name_str | Repositório Institucional da UNL |
| oai_identifier_str | oai:run.unl.pt:10362/158269 |
| organization_str_mv | urn:organizationAcronym:unl |
| person_str_mv | Morgado, Micaela C. Sousa, Mónica Marques, Cláudia Coelho, André B. Costa, Júlio A. Seabra, André |
| publishDate | 2023 |
| repo_facet_str | urn:repositoryAcronym:run{{{_:::_}}}Repositório Institucional da UNL |
| reponame_str | Repositório Institucional da UNL |
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| spelling | engenChildhood obesity continues to represent a growing challenge, and it has been associated with gut microbiota dysbiosis. This study examines the gut microbiota composition in overweight and obese school children and assesses whether a 12-week multidisciplinary intervention can induce changes in the gut microbiota. The intervention, which combined recreational football and nutritional education, was implemented among 15 school children, aged 7–10 years, with a Body Mass Index ≥ 85th percentile. The children were assigned into two groups: Football Group (n = 9) and Nutrition and Football Group (n = 6). Faecal samples were collected at the beginning and end of the program and analysed by sequencing the 16S rRNA gene. Over the intervention, a significant decrease was found collectively for Bifidobacterium genera (p = 0.011) and for Roseburia genera in the Football Group (p = 0.021). The relative abundance of Roseburia (p = 0.002) and Roseburia faecis (p = 0.009) was negatively correlated with moderate to vigorous physical activity (MVPA), while Prevotella copri was positively correlated with MVPA (p = 0.010) and with the daily intake of protein (p = 0.008). Our findings suggest that a multidisciplinary intervention was capable of inducing limited but significant positive changes in the gut microbiota composition in overweight and obese school children.application/pdfenEffects of Physical Activity and Nutrition Education on the Gut Microbiota in Overweight and Obese ChildrenMorgado, Micaela C.Sousa, MónicaMarques, CláudiaCoelho, André B.Costa, Júlio A.Seabra, AndréNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)Centro de Investigação em Tecnologias e Serviços de Saúde (CINTESIS)MDPI - Multidisciplinary Digital Publishing InstituteHostingInstitutionOrganizationalRUNe-mailmailto:run@unl.ptrun@unl.ptISSNIsPartOf2227-9067URNIsPartOfPURE: 72180985URNIsPartOfPURE UUID: 5185b74e-1598-48c4-8da7-ecbf1f6cfafaURNIsPartOfScopus: 85169624710DOIIsPartOf10.3390/children100712422023-09-25T22:19:58Z2023-072023-07-01T00:00:00ZHandlehttp://hdl.handle.net/10362/158269http://purl.org/coar/access_right/c_abf2open accessBifidobacteriumchildhood obesityFirmicutes-to-Bacteroidetes ratiofootballgut microbiotanutritionphysical activityPrevotellaPediatrics, Perinatology, and Child HealthSDG 3 - Good Health and Well-being3409123 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://run.unl.pt/bitstreams/7a1c98d5-3452-4961-ac71-38aaded86c98/download |
| spellingShingle | Effects of Physical Activity and Nutrition Education on the Gut Microbiota in Overweight and Obese Children Morgado, Micaela C. Bifidobacterium childhood obesity Firmicutes-to-Bacteroidetes ratio football gut microbiota nutrition physical activity Prevotella Pediatrics, Perinatology, and Child Health SDG 3 - Good Health and Well-being |
| status | SINGLETON |
| subject.fl_str_mv | Bifidobacterium childhood obesity Firmicutes-to-Bacteroidetes ratio football gut microbiota nutrition physical activity Prevotella Pediatrics, Perinatology, and Child Health SDG 3 - Good Health and Well-being |
| title | Effects of Physical Activity and Nutrition Education on the Gut Microbiota in Overweight and Obese Children |
| title_full | Effects of Physical Activity and Nutrition Education on the Gut Microbiota in Overweight and Obese Children |
| title_fullStr | Effects of Physical Activity and Nutrition Education on the Gut Microbiota in Overweight and Obese Children |
| title_full_unstemmed | Effects of Physical Activity and Nutrition Education on the Gut Microbiota in Overweight and Obese Children |
| title_short | Effects of Physical Activity and Nutrition Education on the Gut Microbiota in Overweight and Obese Children |
| title_sort | Effects of Physical Activity and Nutrition Education on the Gut Microbiota in Overweight and Obese Children |
| topic | Bifidobacterium childhood obesity Firmicutes-to-Bacteroidetes ratio football gut microbiota nutrition physical activity Prevotella Pediatrics, Perinatology, and Child Health SDG 3 - Good Health and Well-being |
| topic_facet | Bifidobacterium childhood obesity Firmicutes-to-Bacteroidetes ratio football gut microbiota nutrition physical activity Prevotella Pediatrics, Perinatology, and Child Health SDG 3 - Good Health and Well-being |
| url | http://hdl.handle.net/10362/158269 |
| visible | 1 |