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Influence of Environmental Factors on Biofilm Formation of Staphylococci Isolated from Wastewater and Surface Water

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Resumo:The presence of biofilms can negatively affect several different areas, such as the food industry, environment, and biomedical sectors. Conditions under which bacteria grow and develop, such as temperature, nutrients, and pH, among others, can largely influence biofilm production. Staphylococcus species survive in the natural environment due to their tolerance to a wide range of temperatures, dryness, dehydration, and low water activity. Therefore, we aimed to evaluate the influence of external environmental factors on the formation of biofilm of staphylococci isolated from hospital wastewater and surface waters. We investigated the biofilm formation of methicillin-resistant and -susceptible S. aureus (MRSA and MSSA) and coagulase-negative staphylococci (CoNS) under various temperatures, pH values, salt concentrations, glucose concentrations, and under anaerobic and aerobic conditions. CoNS had the ability to produce more biofilm biomass than MSSA and MRSA. All environmental factors studied influenced the biofilm formation of staphylococci isolates after 24 h of incubation. Higher biofilm formation was achieved at 4% of NaCl and 0.5% of glucose for MSSA and CoNS, and 1% of NaCl and 1.5% of glucose for MRSA isolates. Biofilm formation of isolates was greater at 25 °C and 37 °C than at 10 °C and 4 °C. pH values between 6 and 8 led to more robust biofilm formation than pH levels of 9 and 5. Although staphylococci are facultative anaerobes, biofilm formation was higher in the presence of oxygen. The results demonstrated that multiple environmental factors affect staphylococci biofilm formation. Different conditions affect differently the biofilm formation of MRSA, MSSA, and CoNS strains.
Autores principais:Silva, Vanessa
Outros Autores:Pereira, José Eduardo; Maltez, Luís; Poeta, Patrícia; Igrejas, Gilberto
Assunto:biofilms coagulase-negative staphylococci environment S. aureus Staphylococcus Immunology and Allergy Molecular Biology General Immunology and Microbiology Microbiology (medical) Infectious Diseases SDG 3 - Good Health and Well-being
Ano:2022
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Universidade Nova de Lisboa
Idioma:inglês
Origem:Repositório Institucional da UNL
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author Silva, Vanessa
author2 Pereira, José Eduardo
Maltez, Luís
Poeta, Patrícia
Igrejas, Gilberto
author2_role author
author
author
author
author_facet Silva, Vanessa
Pereira, José Eduardo
Maltez, Luís
Poeta, Patrícia
Igrejas, Gilberto
author_role author
contributor_name_str_mv LAQV@REQUIMTE
DQ - Departamento de Química
MDPI - Multidisciplinary Digital Publishing Institute
RUN
country_str PT
creators_json_txt [{\"Person.name\":\"Silva, Vanessa\"},{\"Person.name\":\"Pereira, José Eduardo\"},{\"Person.name\":\"Maltez, Luís\"},{\"Person.name\":\"Poeta, Patrícia\"},{\"Person.name\":\"Igrejas, Gilberto\"}]
datacite.contributors.contributor.contributorName.fl_str_mv LAQV@REQUIMTE
DQ - Departamento de Química
MDPI - Multidisciplinary Digital Publishing Institute
RUN
datacite.creators.creator.creatorName.fl_str_mv Silva, Vanessa
Pereira, José Eduardo
Maltez, Luís
Poeta, Patrícia
Igrejas, Gilberto
datacite.date.Accepted.fl_str_mv 2022-09-20T00:00:00Z
datacite.date.available.fl_str_mv 2023-03-15T22:35:08Z
datacite.date.embargoed.fl_str_mv 2023-03-15T22:35:08Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv biofilms
coagulase-negative staphylococci
environment
S. aureus
Staphylococcus
Immunology and Allergy
Molecular Biology
General Immunology and Microbiology
Microbiology (medical)
Infectious Diseases
SDG 3 - Good Health and Well-being
datacite.titles.title.fl_str_mv Influence of Environmental Factors on Biofilm Formation of Staphylococci Isolated from Wastewater and Surface Water
dc.contributor.none.fl_str_mv LAQV@REQUIMTE
DQ - Departamento de Química
MDPI - Multidisciplinary Digital Publishing Institute
RUN
dc.creator.none.fl_str_mv Silva, Vanessa
Pereira, José Eduardo
Maltez, Luís
Poeta, Patrícia
Igrejas, Gilberto
dc.date.Accepted.fl_str_mv 2022-09-20T00:00:00Z
dc.date.available.fl_str_mv 2023-03-15T22:35:08Z
dc.date.embargoed.fl_str_mv 2023-03-15T22:35:08Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10362/150650
dc.language.none.fl_str_mv eng
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.subject.none.fl_str_mv biofilms
coagulase-negative staphylococci
environment
S. aureus
Staphylococcus
Immunology and Allergy
Molecular Biology
General Immunology and Microbiology
Microbiology (medical)
Infectious Diseases
SDG 3 - Good Health and Well-being
dc.title.fl_str_mv Influence of Environmental Factors on Biofilm Formation of Staphylococci Isolated from Wastewater and Surface Water
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description The presence of biofilms can negatively affect several different areas, such as the food industry, environment, and biomedical sectors. Conditions under which bacteria grow and develop, such as temperature, nutrients, and pH, among others, can largely influence biofilm production. Staphylococcus species survive in the natural environment due to their tolerance to a wide range of temperatures, dryness, dehydration, and low water activity. Therefore, we aimed to evaluate the influence of external environmental factors on the formation of biofilm of staphylococci isolated from hospital wastewater and surface waters. We investigated the biofilm formation of methicillin-resistant and -susceptible S. aureus (MRSA and MSSA) and coagulase-negative staphylococci (CoNS) under various temperatures, pH values, salt concentrations, glucose concentrations, and under anaerobic and aerobic conditions. CoNS had the ability to produce more biofilm biomass than MSSA and MRSA. All environmental factors studied influenced the biofilm formation of staphylococci isolates after 24 h of incubation. Higher biofilm formation was achieved at 4% of NaCl and 0.5% of glucose for MSSA and CoNS, and 1% of NaCl and 1.5% of glucose for MRSA isolates. Biofilm formation of isolates was greater at 25 °C and 37 °C than at 10 °C and 4 °C. pH values between 6 and 8 led to more robust biofilm formation than pH levels of 9 and 5. Although staphylococci are facultative anaerobes, biofilm formation was higher in the presence of oxygen. The results demonstrated that multiple environmental factors affect staphylococci biofilm formation. Different conditions affect differently the biofilm formation of MRSA, MSSA, and CoNS strains.
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funding.funder.name_str_mv Fundação para a Ciência e a Tecnologia
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organization_str_mv urn:organizationAcronym:unl
person_str_mv Silva, Vanessa
Pereira, José Eduardo
Maltez, Luís
Poeta, Patrícia
Igrejas, Gilberto
publishDate 2022
repo_facet_str urn:repositoryAcronym:run{{{_:::_}}}Repositório Institucional da UNL
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spelling engenThe presence of biofilms can negatively affect several different areas, such as the food industry, environment, and biomedical sectors. Conditions under which bacteria grow and develop, such as temperature, nutrients, and pH, among others, can largely influence biofilm production. Staphylococcus species survive in the natural environment due to their tolerance to a wide range of temperatures, dryness, dehydration, and low water activity. Therefore, we aimed to evaluate the influence of external environmental factors on the formation of biofilm of staphylococci isolated from hospital wastewater and surface waters. We investigated the biofilm formation of methicillin-resistant and -susceptible S. aureus (MRSA and MSSA) and coagulase-negative staphylococci (CoNS) under various temperatures, pH values, salt concentrations, glucose concentrations, and under anaerobic and aerobic conditions. CoNS had the ability to produce more biofilm biomass than MSSA and MRSA. All environmental factors studied influenced the biofilm formation of staphylococci isolates after 24 h of incubation. Higher biofilm formation was achieved at 4% of NaCl and 0.5% of glucose for MSSA and CoNS, and 1% of NaCl and 1.5% of glucose for MRSA isolates. Biofilm formation of isolates was greater at 25 °C and 37 °C than at 10 °C and 4 °C. pH values between 6 and 8 led to more robust biofilm formation than pH levels of 9 and 5. Although staphylococci are facultative anaerobes, biofilm formation was higher in the presence of oxygen. The results demonstrated that multiple environmental factors affect staphylococci biofilm formation. Different conditions affect differently the biofilm formation of MRSA, MSSA, and CoNS strains.application/pdfenInfluence of Environmental Factors on Biofilm Formation of Staphylococci Isolated from Wastewater and Surface WaterSilva, VanessaPereira, José EduardoMaltez, LuísPoeta, PatríciaIgrejas, GilbertoLAQV@REQUIMTEDQ - Departamento de QuímicaMDPI - Multidisciplinary Digital Publishing InstituteHostingInstitutionOrganizationalRUNe-mailmailto:run@unl.ptrun@unl.ptISSNIsPartOf2076-0817URNIsPartOfPURE: 55918605URNIsPartOfPURE UUID: 4ba5fd4b-2ea1-450a-b94d-d9e9b3b411abURNIsPartOfScopus: 85140831719URNIsPartOfWOS: 000873859700001URNIsPartOfPubMed: 36297126URNIsPartOfPubMedCentral: PMC9611571DOIIsPartOf10.3390/pathogens111010692023-03-15T22:35:08Z2022-09-202022-09-20T00:00:00ZHandlehttp://hdl.handle.net/10362/150650http://purl.org/coar/access_right/c_abf2open accessbiofilmscoagulase-negative staphylococcienvironmentS. aureusStaphylococcusImmunology and AllergyMolecular BiologyGeneral Immunology and MicrobiologyMicrobiology (medical)Infectious DiseasesSDG 3 - Good Health and Well-being2307508 bytesFundação para a Ciência e a TecnologiaAssociated Laboratory for Green Chemistry - Clean Technologies and Processes6817 - DCRRNI IDCrossref Funder IDhttp://doi.org/10.13039/501100001871Fundação para a Ciência e a TecnologiaAssociated Laboratory for Green Chemistry - Clean Technologies and Processes6817 - DCRRNI IDCrossref Funder IDhttp://doi.org/10.13039/501100001871Fundação para a Ciência e a Tecnologiaalterado para: Antimicrobial resistance, clonal diversity and biofilm formation of Staphylococcus aureus and other staphylococci: A One Health approach to a global threat Integrating multiple ‘omics’ analysis of methicillin-resistant Staphylococcus aureus MRSA biofilms: a One Health approach to a global threatPOR_NORTECrossref Funder IDhttp://doi.org/10.13039/501100001871literaturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://run.unl.pt/bitstreams/0d2f74a3-c2e3-4d57-8a9b-968cd4aae26d/download
spellingShingle Influence of Environmental Factors on Biofilm Formation of Staphylococci Isolated from Wastewater and Surface Water
Silva, Vanessa
biofilms
coagulase-negative staphylococci
environment
S. aureus
Staphylococcus
Immunology and Allergy
Molecular Biology
General Immunology and Microbiology
Microbiology (medical)
Infectious Diseases
SDG 3 - Good Health and Well-being
status SINGLETON
subject.fl_str_mv biofilms
coagulase-negative staphylococci
environment
S. aureus
Staphylococcus
Immunology and Allergy
Molecular Biology
General Immunology and Microbiology
Microbiology (medical)
Infectious Diseases
SDG 3 - Good Health and Well-being
title Influence of Environmental Factors on Biofilm Formation of Staphylococci Isolated from Wastewater and Surface Water
title_full Influence of Environmental Factors on Biofilm Formation of Staphylococci Isolated from Wastewater and Surface Water
title_fullStr Influence of Environmental Factors on Biofilm Formation of Staphylococci Isolated from Wastewater and Surface Water
title_full_unstemmed Influence of Environmental Factors on Biofilm Formation of Staphylococci Isolated from Wastewater and Surface Water
title_short Influence of Environmental Factors on Biofilm Formation of Staphylococci Isolated from Wastewater and Surface Water
title_sort Influence of Environmental Factors on Biofilm Formation of Staphylococci Isolated from Wastewater and Surface Water
topic biofilms
coagulase-negative staphylococci
environment
S. aureus
Staphylococcus
Immunology and Allergy
Molecular Biology
General Immunology and Microbiology
Microbiology (medical)
Infectious Diseases
SDG 3 - Good Health and Well-being
topic_facet biofilms
coagulase-negative staphylococci
environment
S. aureus
Staphylococcus
Immunology and Allergy
Molecular Biology
General Immunology and Microbiology
Microbiology (medical)
Infectious Diseases
SDG 3 - Good Health and Well-being
url http://hdl.handle.net/10362/150650
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