Publicação
Development of Emulsions Containing L-Ascorbic Acid and α-Tocopherol Based on the Polysaccharide FucoPol
| Resumo: | The main function of vitamin C, as an antioxidant, is to combat free radicals and prevent premature aging, smoothing wrinkles and expression lines. In addition, it acts directly on depigmentation and prevention of blemishes on the skin. In this study, natural oils (30 wt.%) and α-tocopherol (2.5 wt.%) containing oil-in-water (O/W) emulsions stabilized with the bacterial fucose-rich polysaccharide FucoPol were formulated, adding L-ascorbic acid as an antioxidant. The optimized formulations were obtained with 8.0 wt.% L-ascorbic acid for the Olea europaea oil formulation (C1) with a ƞ value of 2.71 Pa.s (measured at shear rate of 2.3 s−1) and E24 = 96% and with 15 wt.% L-ascorbic acid for the Prunus amygdalus dulcis formulation (C2) with a ƞ value of 5.15 Pa.s (at a shear rate of 2.3 s−1) and E24 = 99%. The stability of the FucoPol-based formulations was investigated over 45 days at 4 °C, 20 °C, and 30 °C. The results showed that all formulations maintained the organoleptic characteristics, with pH variations (5.7–6.8 for C1, and 5.5–6.03 for C2) within the regulations for cosmetic products (4 ≤ pH ≤ 7). The accelerated stability tests proved the formulations’ stability at 4 °C with EI = 95% for C1 and EI = 100% for C2. The rheological assessment demonstrated that the formulation presents a shear-thinning and liquid-like behavior. Regarding textural parameters, formulations C1 and C2 displayed an increase in firmness and consistency with similar spreadability during the shelf life. These findings further demonstrate FucoPol’s functional properties, acting as an emulsifier and stabilizer polysaccharide in cosmetic formulations containing L-ascorbic acid. |
|---|---|
| Autores principais: | Baptista, Sílvia |
| Outros Autores: | Baptista, Filipa; Freitas, Filomena |
| Assunto: | antioxidant FucoPol L-ascorbic acid O/W emulsion rheology α-tocopherol Surgery Chemical Engineering (miscellaneous) Ageing Pharmaceutical Science Dermatology |
| Ano: | 2023 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade Nova de Lisboa |
| Idioma: | inglês |
| Origem: | Repositório Institucional da UNL |
| _version_ | 1868983746351333376 |
|---|---|
| author | Baptista, Sílvia |
| author2 | Baptista, Filipa Freitas, Filomena |
| author2_role | author author |
| author_facet | Baptista, Sílvia Baptista, Filipa Freitas, Filomena |
| author_role | author |
| contributor_name_str_mv | DQ - Departamento de Química UCIBIO - Applied Molecular Biosciences Unit MDPI - Multidisciplinary Digital Publishing Institute RUN |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Baptista, Sílvia\"},{\"Person.name\":\"Baptista, Filipa\"},{\"Person.name\":\"Freitas, Filomena\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | DQ - Departamento de Química UCIBIO - Applied Molecular Biosciences Unit MDPI - Multidisciplinary Digital Publishing Institute RUN |
| datacite.creators.creator.creatorName.fl_str_mv | Baptista, Sílvia Baptista, Filipa Freitas, Filomena |
| datacite.date.Accepted.fl_str_mv | 2023-03-27T00:00:00Z |
| datacite.date.available.fl_str_mv | 2023-09-27T22:26:10Z |
| datacite.date.embargoed.fl_str_mv | 2023-09-27T22:26:10Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | antioxidant FucoPol L-ascorbic acid O/W emulsion rheology α-tocopherol Surgery Chemical Engineering (miscellaneous) Ageing Pharmaceutical Science Dermatology |
| datacite.titles.title.fl_str_mv | Development of Emulsions Containing L-Ascorbic Acid and α-Tocopherol Based on the Polysaccharide FucoPol Stability Evaluation and Rheological and Texture Assessment |
| dc.contributor.none.fl_str_mv | DQ - Departamento de Química UCIBIO - Applied Molecular Biosciences Unit MDPI - Multidisciplinary Digital Publishing Institute RUN |
| dc.creator.none.fl_str_mv | Baptista, Sílvia Baptista, Filipa Freitas, Filomena |
| dc.date.Accepted.fl_str_mv | 2023-03-27T00:00:00Z |
| dc.date.available.fl_str_mv | 2023-09-27T22:26:10Z |
| dc.date.embargoed.fl_str_mv | 2023-09-27T22:26:10Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | http://hdl.handle.net/10362/158384 |
| dc.language.none.fl_str_mv | eng |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | antioxidant FucoPol L-ascorbic acid O/W emulsion rheology α-tocopherol Surgery Chemical Engineering (miscellaneous) Ageing Pharmaceutical Science Dermatology |
| dc.title.fl_str_mv | Development of Emulsions Containing L-Ascorbic Acid and α-Tocopherol Based on the Polysaccharide FucoPol Stability Evaluation and Rheological and Texture Assessment |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | The main function of vitamin C, as an antioxidant, is to combat free radicals and prevent premature aging, smoothing wrinkles and expression lines. In addition, it acts directly on depigmentation and prevention of blemishes on the skin. In this study, natural oils (30 wt.%) and α-tocopherol (2.5 wt.%) containing oil-in-water (O/W) emulsions stabilized with the bacterial fucose-rich polysaccharide FucoPol were formulated, adding L-ascorbic acid as an antioxidant. The optimized formulations were obtained with 8.0 wt.% L-ascorbic acid for the Olea europaea oil formulation (C1) with a ƞ value of 2.71 Pa.s (measured at shear rate of 2.3 s−1) and E24 = 96% and with 15 wt.% L-ascorbic acid for the Prunus amygdalus dulcis formulation (C2) with a ƞ value of 5.15 Pa.s (at a shear rate of 2.3 s−1) and E24 = 99%. The stability of the FucoPol-based formulations was investigated over 45 days at 4 °C, 20 °C, and 30 °C. The results showed that all formulations maintained the organoleptic characteristics, with pH variations (5.7–6.8 for C1, and 5.5–6.03 for C2) within the regulations for cosmetic products (4 ≤ pH ≤ 7). The accelerated stability tests proved the formulations’ stability at 4 °C with EI = 95% for C1 and EI = 100% for C2. The rheological assessment demonstrated that the formulation presents a shear-thinning and liquid-like behavior. Regarding textural parameters, formulations C1 and C2 displayed an increase in firmness and consistency with similar spreadability during the shelf life. These findings further demonstrate FucoPol’s functional properties, acting as an emulsifier and stabilizer polysaccharide in cosmetic formulations containing L-ascorbic acid. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| fulltext.url.fl_str_mv | https://run.unl.pt/bitstreams/a075f0a1-a9aa-47ec-b811-828b1b17f635/download |
| funder_facet_str_mv | FCT{{{_:::_}}}Fundação para a Ciência e a Tecnologia FCT{{{_:::_}}}Fundação para a Ciência e a Tecnologia FCT{{{_:::_}}}Fundação para a Ciência e a Tecnologia |
| funding.funder.alternateName_str_mv | FCT FCT FCT |
| funding.funder.identifier_str_mv | http://doi.org/10.13039/501100001871 http://doi.org/10.13039/501100001871 http://doi.org/10.13039/501100001871 |
| funding.funder.name_str_mv | Fundação para a Ciência e a Tecnologia Fundação para a Ciência e a Tecnologia Fundação para a Ciência e a Tecnologia |
| funding.name_str_mv | 6817 - DCRRNI ID 6817 - DCRRNI ID 6817 - DCRRNI ID |
| id | run_de60fe244cc782889386b42e58003e39 |
| identifier.url.fl_str_mv | http://hdl.handle.net/10362/158384 |
| inst_facet_str | urn:organizationAcronym:unl{{{_:::_}}}Universidade Nova de Lisboa |
| instacron_str | unl |
| institution | Universidade Nova de Lisboa |
| instname_str | Universidade Nova de Lisboa |
| language | eng |
| network_acronym_str | run |
| network_name_str | Repositório Institucional da UNL |
| oai_identifier_str | oai:run.unl.pt:10362/158384 |
| organization_str_mv | urn:organizationAcronym:unl |
| person_str_mv | Baptista, Sílvia Baptista, Filipa Freitas, Filomena |
| publishDate | 2023 |
| repo_facet_str | urn:repositoryAcronym:run{{{_:::_}}}Repositório Institucional da UNL |
| reponame_str | Repositório Institucional da UNL |
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| spelling | engenThe main function of vitamin C, as an antioxidant, is to combat free radicals and prevent premature aging, smoothing wrinkles and expression lines. In addition, it acts directly on depigmentation and prevention of blemishes on the skin. In this study, natural oils (30 wt.%) and α-tocopherol (2.5 wt.%) containing oil-in-water (O/W) emulsions stabilized with the bacterial fucose-rich polysaccharide FucoPol were formulated, adding L-ascorbic acid as an antioxidant. The optimized formulations were obtained with 8.0 wt.% L-ascorbic acid for the Olea europaea oil formulation (C1) with a ƞ value of 2.71 Pa.s (measured at shear rate of 2.3 s−1) and E24 = 96% and with 15 wt.% L-ascorbic acid for the Prunus amygdalus dulcis formulation (C2) with a ƞ value of 5.15 Pa.s (at a shear rate of 2.3 s−1) and E24 = 99%. The stability of the FucoPol-based formulations was investigated over 45 days at 4 °C, 20 °C, and 30 °C. The results showed that all formulations maintained the organoleptic characteristics, with pH variations (5.7–6.8 for C1, and 5.5–6.03 for C2) within the regulations for cosmetic products (4 ≤ pH ≤ 7). The accelerated stability tests proved the formulations’ stability at 4 °C with EI = 95% for C1 and EI = 100% for C2. The rheological assessment demonstrated that the formulation presents a shear-thinning and liquid-like behavior. Regarding textural parameters, formulations C1 and C2 displayed an increase in firmness and consistency with similar spreadability during the shelf life. These findings further demonstrate FucoPol’s functional properties, acting as an emulsifier and stabilizer polysaccharide in cosmetic formulations containing L-ascorbic acid.application/pdfenDevelopment of Emulsions Containing L-Ascorbic Acid and α-Tocopherol Based on the Polysaccharide FucoPolSubtitleenStability Evaluation and Rheological and Texture AssessmentBaptista, SílviaBaptista, FilipaFreitas, FilomenaDQ - Departamento de QuímicaUCIBIO - Applied Molecular Biosciences UnitMDPI - Multidisciplinary Digital Publishing InstituteHostingInstitutionOrganizationalRUNe-mailmailto:run@unl.ptrun@unl.ptURNIsPartOfPURE: 72580016URNIsPartOfPURE UUID: 6fe2c92c-cd1f-49a0-9aca-18010e901861URNIsPartOfScopus: 85153774447URNIsPartOfWOS: 000980920200001URNIsPartOfORCID: /0000-0002-9430-4640/work/151386214DOIIsPartOf10.3390/cosmetics100200562023-09-27T22:26:10Z2023-03-272023-03-27T00:00:00ZHandlehttp://hdl.handle.net/10362/158384http://purl.org/coar/access_right/c_abf2open accessantioxidantFucoPolL-ascorbic acidO/W emulsionrheologyα-tocopherolSurgeryChemical Engineering (miscellaneous)AgeingPharmaceutical ScienceDermatology3677327 bytesFundação para a Ciência e a TecnologiaApplied Molecular Biosciences Unit6817 - DCRRNI IDCrossref Funder IDhttp://doi.org/10.13039/501100001871Fundação para a Ciência e a TecnologiaApplied Molecular Biosciences Unit6817 - DCRRNI IDCrossref Funder IDhttp://doi.org/10.13039/501100001871Fundação para a Ciência e a TecnologiaInstitute for Health and Bioeconomy6817 - DCRRNI IDCrossref Funder IDhttp://doi.org/10.13039/501100001871literaturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://run.unl.pt/bitstreams/a075f0a1-a9aa-47ec-b811-828b1b17f635/download |
| spellingShingle | Development of Emulsions Containing L-Ascorbic Acid and α-Tocopherol Based on the Polysaccharide FucoPol Baptista, Sílvia antioxidant FucoPol L-ascorbic acid O/W emulsion rheology α-tocopherol Surgery Chemical Engineering (miscellaneous) Ageing Pharmaceutical Science Dermatology |
| status | SINGLETON |
| subject.fl_str_mv | antioxidant FucoPol L-ascorbic acid O/W emulsion rheology α-tocopherol Surgery Chemical Engineering (miscellaneous) Ageing Pharmaceutical Science Dermatology |
| title | Development of Emulsions Containing L-Ascorbic Acid and α-Tocopherol Based on the Polysaccharide FucoPol |
| title_full | Development of Emulsions Containing L-Ascorbic Acid and α-Tocopherol Based on the Polysaccharide FucoPol |
| title_fullStr | Development of Emulsions Containing L-Ascorbic Acid and α-Tocopherol Based on the Polysaccharide FucoPol |
| title_full_unstemmed | Development of Emulsions Containing L-Ascorbic Acid and α-Tocopherol Based on the Polysaccharide FucoPol |
| title_short | Development of Emulsions Containing L-Ascorbic Acid and α-Tocopherol Based on the Polysaccharide FucoPol |
| title_sort | Development of Emulsions Containing L-Ascorbic Acid and α-Tocopherol Based on the Polysaccharide FucoPol |
| topic | antioxidant FucoPol L-ascorbic acid O/W emulsion rheology α-tocopherol Surgery Chemical Engineering (miscellaneous) Ageing Pharmaceutical Science Dermatology |
| topic_facet | antioxidant FucoPol L-ascorbic acid O/W emulsion rheology α-tocopherol Surgery Chemical Engineering (miscellaneous) Ageing Pharmaceutical Science Dermatology |
| url | http://hdl.handle.net/10362/158384 |
| visible | 1 |