Publicação

Enhancing Alzheimer's Disease Diagnosis and Care by Focusing on Plasma Biomarkers for Identifying Mild Cognitive Impairment

Ver documento

Detalhes bibliográficos
Resumo:Biomarkers that accurately identify mild cognitive impairment (MCI) are of greater importance for Alzheimer's disease (AD) management and treatment. On the other hand, blood-based biomarkers are not only more practical but also less invasive than the common cerebrospinal fluid biomarkers. In their report in the Journal of Alzheimer's Disease, Wang and collaborators identified 67 upregulated and 220 downregulated long noncoding RNAs (lncRNAs). They further demonstrated that 4 of these lncRNAs could discriminate MCI from cognitively healthy individuals. Apart from their significance as potential biomarkers for MCI diagnosis, these lncRNAs can offer additional information on the cellular mechanisms of AD pathology.
Autores principais:Cardoso, Remy
Outros Autores:Teunissen, Charlotte E.; Oliveira, Catarina Resende
Assunto:Alzheimer's disease biomarkers lncRNA mild cognitive impairment plasma General Neuroscience Clinical Psychology Geriatrics and Gerontology Psychiatry and Mental health SDG 3 - Good Health and Well-being
Ano:2024
País:Portugal
Tipo de documento:recensão
Tipo de acesso:acesso aberto
Instituição associada:Universidade Nova de Lisboa
Idioma:inglês
Origem:Repositório Institucional da UNL

Registos relacionados

Registos relacionados