Publicação
Seroprevalência de anticorpos contra o sarampo em profissionais de saúde de um hospital central em Portugal
| Resumo: | INTRODUCTION: Immunity against measles may result from previous contact with the virus or vaccination. In this study we aimed to evaluate the prevalence of immunity to measles in healthcare professionals of a central hospital. MATERIAL AND METHODS: Retrospective study, with description of the results of measles-specific IgG assay in healthcare professionals, between May 2010 and March 2018. RESULTS: The results of 1339 healthcare professionals were analyzed. The average age was 39.3 ± 10.11 years, 71.1% female. The prevalence of positive IgG was 81.5%, higher among professionals in the age groups 40 - 49 and over 50 years (91.9% and 94.6% respectively). Healthcare professionals who presented negative or equivocal IgG were mostly under 40 years old (83.1%) (p < 0.05). DISCUSSION: The prevalence of serological immunity to measles in healthcare professionals was found to be lower than in other studies. That may be due to differences between the characteristics of the studied samples. Susceptibility to measles was higher in lower age groups. These results may reflect low vaccination coverage in this age group, an incomplete vaccination schedule, or the possibility of older healthcare professionals having the disease, which may confer an immune response with higher IgG levels. CONCLUSION: Knowing the prevalence of susceptibility to measles in healthcare professionals enabled the establishment of prevention strategies for outbreaks that may occur. Vaccination remains the best preventative measure, but a third dose of vaccine may be considered in certain epidemiological contexts, particularly in the youngest exposed healthcare professionals. |
|---|---|
| Autores principais: | Navarro Morales, Gary |
| Outros Autores: | Shapovalova, Olena; Sacadura-Leite, Ema |
| Assunto: | SDG 3 - Good Health and Well-being |
| Ano: | 2021 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade Nova de Lisboa |
| Idioma: | português |
| Origem: | Repositório Institucional da UNL |
| _version_ | 1868983898768146432 |
|---|---|
| author | Navarro Morales, Gary |
| author2 | Shapovalova, Olena Sacadura-Leite, Ema |
| author2_role | author author |
| author_facet | Navarro Morales, Gary Shapovalova, Olena Sacadura-Leite, Ema |
| author_role | author |
| contributor_name_str_mv | Centro de Investigação em Saúde Pública (CISP/PHRC) Escola Nacional de Saúde Pública (ENSP) Biblioteca Nacional de Portugal, Centro de Estudos Históricos, CELOM RUN |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Navarro Morales, Gary\"},{\"Person.name\":\"Shapovalova, Olena\"},{\"Person.name\":\"Sacadura-Leite, Ema\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Centro de Investigação em Saúde Pública (CISP/PHRC) Escola Nacional de Saúde Pública (ENSP) Biblioteca Nacional de Portugal, Centro de Estudos Históricos, CELOM RUN |
| datacite.creators.creator.creatorName.fl_str_mv | Navarro Morales, Gary Shapovalova, Olena Sacadura-Leite, Ema |
| datacite.date.Accepted.fl_str_mv | 2021-01-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2020-12-30T05:04:35Z |
| datacite.date.embargoed.fl_str_mv | 2020-12-30T05:04:35Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | SDG 3 - Good Health and Well-being |
| datacite.titles.title.fl_str_mv | Seroprevalência de anticorpos contra o sarampo em profissionais de saúde de um hospital central em Portugal Seroprevalence of measles antibodies in healthcare professionals in a central hospital in Portugal |
| dc.contributor.none.fl_str_mv | Centro de Investigação em Saúde Pública (CISP/PHRC) Escola Nacional de Saúde Pública (ENSP) Biblioteca Nacional de Portugal, Centro de Estudos Históricos, CELOM RUN |
| dc.creator.none.fl_str_mv | Navarro Morales, Gary Shapovalova, Olena Sacadura-Leite, Ema |
| dc.date.Accepted.fl_str_mv | 2021-01-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2020-12-30T05:04:35Z |
| dc.date.embargoed.fl_str_mv | 2020-12-30T05:04:35Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | http://hdl.handle.net/10362/109487 |
| dc.language.none.fl_str_mv | por |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | SDG 3 - Good Health and Well-being |
| dc.title.fl_str_mv | Seroprevalência de anticorpos contra o sarampo em profissionais de saúde de um hospital central em Portugal Seroprevalence of measles antibodies in healthcare professionals in a central hospital in Portugal |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | INTRODUCTION: Immunity against measles may result from previous contact with the virus or vaccination. In this study we aimed to evaluate the prevalence of immunity to measles in healthcare professionals of a central hospital. MATERIAL AND METHODS: Retrospective study, with description of the results of measles-specific IgG assay in healthcare professionals, between May 2010 and March 2018. RESULTS: The results of 1339 healthcare professionals were analyzed. The average age was 39.3 ± 10.11 years, 71.1% female. The prevalence of positive IgG was 81.5%, higher among professionals in the age groups 40 - 49 and over 50 years (91.9% and 94.6% respectively). Healthcare professionals who presented negative or equivocal IgG were mostly under 40 years old (83.1%) (p < 0.05). DISCUSSION: The prevalence of serological immunity to measles in healthcare professionals was found to be lower than in other studies. That may be due to differences between the characteristics of the studied samples. Susceptibility to measles was higher in lower age groups. These results may reflect low vaccination coverage in this age group, an incomplete vaccination schedule, or the possibility of older healthcare professionals having the disease, which may confer an immune response with higher IgG levels. CONCLUSION: Knowing the prevalence of susceptibility to measles in healthcare professionals enabled the establishment of prevention strategies for outbreaks that may occur. Vaccination remains the best preventative measure, but a third dose of vaccine may be considered in certain epidemiological contexts, particularly in the youngest exposed healthcare professionals. |
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| eu_rights_str_mv | openAccess |
| format | article |
| fulltext.url.fl_str_mv | https://run.unl.pt/bitstreams/cdf58f85-844b-4e92-8d46-8ee9454f1330/download |
| id | run_eb66ff04e845ff35877d90f2f9cf06e8 |
| identifier.url.fl_str_mv | http://hdl.handle.net/10362/109487 |
| inst_facet_str | urn:organizationAcronym:unl{{{_:::_}}}Universidade Nova de Lisboa |
| instacron_str | unl |
| institution | Universidade Nova de Lisboa |
| instname_str | Universidade Nova de Lisboa |
| language | por |
| network_acronym_str | run |
| network_name_str | Repositório Institucional da UNL |
| oai_identifier_str | oai:run.unl.pt:10362/109487 |
| organization_str_mv | urn:organizationAcronym:unl |
| person_str_mv | Navarro Morales, Gary Shapovalova, Olena Sacadura-Leite, Ema |
| publishDate | 2021 |
| repo_facet_str | urn:repositoryAcronym:run{{{_:::_}}}Repositório Institucional da UNL |
| reponame_str | Repositório Institucional da UNL |
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| spelling | porenINTRODUCTION: Immunity against measles may result from previous contact with the virus or vaccination. In this study we aimed to evaluate the prevalence of immunity to measles in healthcare professionals of a central hospital. MATERIAL AND METHODS: Retrospective study, with description of the results of measles-specific IgG assay in healthcare professionals, between May 2010 and March 2018. RESULTS: The results of 1339 healthcare professionals were analyzed. The average age was 39.3 ± 10.11 years, 71.1% female. The prevalence of positive IgG was 81.5%, higher among professionals in the age groups 40 - 49 and over 50 years (91.9% and 94.6% respectively). Healthcare professionals who presented negative or equivocal IgG were mostly under 40 years old (83.1%) (p < 0.05). DISCUSSION: The prevalence of serological immunity to measles in healthcare professionals was found to be lower than in other studies. That may be due to differences between the characteristics of the studied samples. Susceptibility to measles was higher in lower age groups. These results may reflect low vaccination coverage in this age group, an incomplete vaccination schedule, or the possibility of older healthcare professionals having the disease, which may confer an immune response with higher IgG levels. CONCLUSION: Knowing the prevalence of susceptibility to measles in healthcare professionals enabled the establishment of prevention strategies for outbreaks that may occur. Vaccination remains the best preventative measure, but a third dose of vaccine may be considered in certain epidemiological contexts, particularly in the youngest exposed healthcare professionals.application/pdfptSeroprevalência de anticorpos contra o sarampo em profissionais de saúde de um hospital central em PortugalAlternativeTitleenSeroprevalence of measles antibodies in healthcare professionals in a central hospital in PortugalNavarro Morales, GaryShapovalova, OlenaSacadura-Leite, EmaCentro de Investigação em Saúde Pública (CISP/PHRC)Escola Nacional de Saúde Pública (ENSP)Biblioteca Nacional de Portugal, Centro de Estudos Históricos, CELOMHostingInstitutionOrganizationalRUNe-mailmailto:run@unl.ptrun@unl.ptISSNIsPartOf1646-0758URNIsPartOfPURE: 27089678URNIsPartOfPURE UUID: 488e9f91-7aa0-449a-b93f-e95b81839088URNIsPartOfPubMed: 33320081URNIsPartOfWOS: 000614876600006URNIsPartOfScopus: 85098956568DOIIsPartOf10.20344/amp.129072020-12-30T05:04:35Z20212021-01-01T00:00:00ZHandlehttp://hdl.handle.net/10362/109487http://purl.org/coar/access_right/c_abf2open accessSDG 3 - Good Health and Well-being452134 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://run.unl.pt/bitstreams/cdf58f85-844b-4e92-8d46-8ee9454f1330/download |
| spellingShingle | Seroprevalência de anticorpos contra o sarampo em profissionais de saúde de um hospital central em Portugal Navarro Morales, Gary SDG 3 - Good Health and Well-being |
| status | SINGLETON |
| subject.fl_str_mv | SDG 3 - Good Health and Well-being |
| title | Seroprevalência de anticorpos contra o sarampo em profissionais de saúde de um hospital central em Portugal |
| title_full | Seroprevalência de anticorpos contra o sarampo em profissionais de saúde de um hospital central em Portugal |
| title_fullStr | Seroprevalência de anticorpos contra o sarampo em profissionais de saúde de um hospital central em Portugal |
| title_full_unstemmed | Seroprevalência de anticorpos contra o sarampo em profissionais de saúde de um hospital central em Portugal |
| title_short | Seroprevalência de anticorpos contra o sarampo em profissionais de saúde de um hospital central em Portugal |
| title_sort | Seroprevalência de anticorpos contra o sarampo em profissionais de saúde de um hospital central em Portugal |
| topic | SDG 3 - Good Health and Well-being |
| topic_facet | SDG 3 - Good Health and Well-being |
| url | http://hdl.handle.net/10362/109487 |
| visible | 1 |