Publicação
Synergistic use of NADES and assisted extraction technologies for recovery and stabilization of bioactive compounds in Beta vulgaris L. peels
| Resumo: | This work concerns the use of Natural Deep Eutectic Systems (NADES) as sustainable extraction solvents to obtain a bioactive extract, from beetroot peels (BRP), that can be used in food or cosmetic applications. BRP are considered a agrifood waste and often underutilized, although they are rich in phytochemicals with bioactive properties (antioxidant, anti-inflammatory, neuroprotective, and anti-carcinogenic). In this work, the objective was to develop a sustainable, efficient, and extraction method of those valuable compounds, using NADES as solvents and efficient extraction methods. Furthermore, the role of NADES in the stabilization and preservation of these bioactive compounds was also studied. Among the various NADES tested, the one composed of betaine and glycerol (BG), showed the highest extraction efficiency and resulted in extracts with superior antioxidant activity. Optimized extraction conditions were found to be 40°C using a 1:20 solid-to-liquid ratio, with BG. The use of NADES not only improved extraction yield, but also improved the stability of BRP bioactive compounds over a longer period of time. This allows for the extract to be used together with NADES, as a liquid, without the need to remove the extraction solvent. The results confirm that NADES are a promising alternative to conventional solvents and have potential uses in nutraceutical or functional food applications. The study underscores the potential of BRP as a sustainable source of natural antioxidants and highlights a circular approach to waste utilization. |
|---|---|
| Autores principais: | Rente, D. |
| Outros Autores: | Craveiro, R.; Paiva, A.; Duarte, Ana Rita C. |
| Assunto: | Antioxidant activity Beetroot peels Bioactive extracts Natural deep eutectic systems (NADES) Stabilizing activity Biotechnology Food Science Biochemistry General Chemical Engineering |
| Ano: | 2026 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade Nova de Lisboa |
| Idioma: | inglês |
| Origem: | Repositório Institucional da UNL |
| _version_ | 1868984258203222016 |
|---|---|
| author | Rente, D. |
| author2 | Craveiro, R. Paiva, A. Duarte, Ana Rita C. |
| author2_role | author author author |
| author_facet | Rente, D. Craveiro, R. Paiva, A. Duarte, Ana Rita C. |
| author_role | author |
| contributor_name_str_mv | DQ - Departamento de Química LAQV@REQUIMTE Institution of Chemical Engineers; 1999 RUN |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Rente, D.\"},{\"Person.name\":\"Craveiro, R.\"},{\"Person.name\":\"Paiva, A.\"},{\"Person.name\":\"Duarte, Ana Rita C.\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | DQ - Departamento de Química LAQV@REQUIMTE Institution of Chemical Engineers; 1999 RUN |
| datacite.creators.creator.creatorName.fl_str_mv | Rente, D. Craveiro, R. Paiva, A. Duarte, Ana Rita C. |
| datacite.date.Accepted.fl_str_mv | 2026-03-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2026-04-29T10:55:01Z |
| datacite.date.embargoed.fl_str_mv | 2026-04-29T10:55:01Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Antioxidant activity Beetroot peels Bioactive extracts Natural deep eutectic systems (NADES) Stabilizing activity Biotechnology Food Science Biochemistry General Chemical Engineering |
| datacite.titles.title.fl_str_mv | Synergistic use of NADES and assisted extraction technologies for recovery and stabilization of bioactive compounds in Beta vulgaris L. peels |
| dc.contributor.none.fl_str_mv | DQ - Departamento de Química LAQV@REQUIMTE Institution of Chemical Engineers; 1999 RUN |
| dc.creator.none.fl_str_mv | Rente, D. Craveiro, R. Paiva, A. Duarte, Ana Rita C. |
| dc.date.Accepted.fl_str_mv | 2026-03-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2026-04-29T10:55:01Z |
| dc.date.embargoed.fl_str_mv | 2026-04-29T10:55:01Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | http://hdl.handle.net/10362/202669 |
| dc.language.none.fl_str_mv | eng |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | Antioxidant activity Beetroot peels Bioactive extracts Natural deep eutectic systems (NADES) Stabilizing activity Biotechnology Food Science Biochemistry General Chemical Engineering |
| dc.title.fl_str_mv | Synergistic use of NADES and assisted extraction technologies for recovery and stabilization of bioactive compounds in Beta vulgaris L. peels |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | This work concerns the use of Natural Deep Eutectic Systems (NADES) as sustainable extraction solvents to obtain a bioactive extract, from beetroot peels (BRP), that can be used in food or cosmetic applications. BRP are considered a agrifood waste and often underutilized, although they are rich in phytochemicals with bioactive properties (antioxidant, anti-inflammatory, neuroprotective, and anti-carcinogenic). In this work, the objective was to develop a sustainable, efficient, and extraction method of those valuable compounds, using NADES as solvents and efficient extraction methods. Furthermore, the role of NADES in the stabilization and preservation of these bioactive compounds was also studied. Among the various NADES tested, the one composed of betaine and glycerol (BG), showed the highest extraction efficiency and resulted in extracts with superior antioxidant activity. Optimized extraction conditions were found to be 40°C using a 1:20 solid-to-liquid ratio, with BG. The use of NADES not only improved extraction yield, but also improved the stability of BRP bioactive compounds over a longer period of time. This allows for the extract to be used together with NADES, as a liquid, without the need to remove the extraction solvent. The results confirm that NADES are a promising alternative to conventional solvents and have potential uses in nutraceutical or functional food applications. The study underscores the potential of BRP as a sustainable source of natural antioxidants and highlights a circular approach to waste utilization. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| fulltext.url.fl_str_mv | https://run.unl.pt/bitstreams/f4665ead-96ef-4cd1-8a78-8361f074c6c7/download |
| id | run_fb63e321d0ef3a36a5a0bcdd20bbc65e |
| identifier.url.fl_str_mv | http://hdl.handle.net/10362/202669 |
| inst_facet_str | urn:organizationAcronym:unl{{{_:::_}}}Universidade Nova de Lisboa |
| instacron_str | unl |
| institution | Universidade Nova de Lisboa |
| instname_str | Universidade Nova de Lisboa |
| language | eng |
| network_acronym_str | run |
| network_name_str | Repositório Institucional da UNL |
| oai_identifier_str | oai:run.unl.pt:10362/202669 |
| organization_str_mv | urn:organizationAcronym:unl |
| person_str_mv | Rente, D. Craveiro, R. Paiva, A. Duarte, Ana Rita C. |
| publishDate | 2026 |
| repo_facet_str | urn:repositoryAcronym:run{{{_:::_}}}Repositório Institucional da UNL |
| reponame_str | Repositório Institucional da UNL |
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| service_str_mv | urn:repositoryAcronym:run |
| spelling | engenThis work concerns the use of Natural Deep Eutectic Systems (NADES) as sustainable extraction solvents to obtain a bioactive extract, from beetroot peels (BRP), that can be used in food or cosmetic applications. BRP are considered a agrifood waste and often underutilized, although they are rich in phytochemicals with bioactive properties (antioxidant, anti-inflammatory, neuroprotective, and anti-carcinogenic). In this work, the objective was to develop a sustainable, efficient, and extraction method of those valuable compounds, using NADES as solvents and efficient extraction methods. Furthermore, the role of NADES in the stabilization and preservation of these bioactive compounds was also studied. Among the various NADES tested, the one composed of betaine and glycerol (BG), showed the highest extraction efficiency and resulted in extracts with superior antioxidant activity. Optimized extraction conditions were found to be 40°C using a 1:20 solid-to-liquid ratio, with BG. The use of NADES not only improved extraction yield, but also improved the stability of BRP bioactive compounds over a longer period of time. This allows for the extract to be used together with NADES, as a liquid, without the need to remove the extraction solvent. The results confirm that NADES are a promising alternative to conventional solvents and have potential uses in nutraceutical or functional food applications. The study underscores the potential of BRP as a sustainable source of natural antioxidants and highlights a circular approach to waste utilization.application/pdfenSynergistic use of NADES and assisted extraction technologies for recovery and stabilization of bioactive compounds in Beta vulgaris L. peelsRente, D.Craveiro, R.Paiva, A.Duarte, Ana Rita C.DQ - Departamento de QuímicaLAQV@REQUIMTEInstitution of Chemical Engineers; 1999HostingInstitutionOrganizationalRUNe-mailmailto:run@unl.ptrun@unl.ptISSNIsPartOf0960-3085URNIsPartOfPURE: 158809940URNIsPartOfPURE UUID: 98d4df2a-9a50-4bd9-9e0f-1b4de3fe5e29URNIsPartOfScopus: 105028995329URNIsPartOfWOS: 001684013000001URNIsPartOfORCID: /0000-0003-0800-0112/work/213285031DOIIsPartOf10.1016/j.fbp.2025.12.0192026-04-29T10:55:01Z2026-032026-03-01T00:00:00ZHandlehttp://hdl.handle.net/10362/202669http://purl.org/coar/access_right/c_abf2open accessAntioxidant activityBeetroot peelsBioactive extractsNatural deep eutectic systems (NADES)Stabilizing activityBiotechnologyFood ScienceBiochemistryGeneral Chemical Engineering2610812 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://run.unl.pt/bitstreams/f4665ead-96ef-4cd1-8a78-8361f074c6c7/download |
| spellingShingle | Synergistic use of NADES and assisted extraction technologies for recovery and stabilization of bioactive compounds in Beta vulgaris L. peels Rente, D. Antioxidant activity Beetroot peels Bioactive extracts Natural deep eutectic systems (NADES) Stabilizing activity Biotechnology Food Science Biochemistry General Chemical Engineering |
| status | SINGLETON |
| subject.fl_str_mv | Antioxidant activity Beetroot peels Bioactive extracts Natural deep eutectic systems (NADES) Stabilizing activity Biotechnology Food Science Biochemistry General Chemical Engineering |
| title | Synergistic use of NADES and assisted extraction technologies for recovery and stabilization of bioactive compounds in Beta vulgaris L. peels |
| title_full | Synergistic use of NADES and assisted extraction technologies for recovery and stabilization of bioactive compounds in Beta vulgaris L. peels |
| title_fullStr | Synergistic use of NADES and assisted extraction technologies for recovery and stabilization of bioactive compounds in Beta vulgaris L. peels |
| title_full_unstemmed | Synergistic use of NADES and assisted extraction technologies for recovery and stabilization of bioactive compounds in Beta vulgaris L. peels |
| title_short | Synergistic use of NADES and assisted extraction technologies for recovery and stabilization of bioactive compounds in Beta vulgaris L. peels |
| title_sort | Synergistic use of NADES and assisted extraction technologies for recovery and stabilization of bioactive compounds in Beta vulgaris L. peels |
| topic | Antioxidant activity Beetroot peels Bioactive extracts Natural deep eutectic systems (NADES) Stabilizing activity Biotechnology Food Science Biochemistry General Chemical Engineering |
| topic_facet | Antioxidant activity Beetroot peels Bioactive extracts Natural deep eutectic systems (NADES) Stabilizing activity Biotechnology Food Science Biochemistry General Chemical Engineering |
| url | http://hdl.handle.net/10362/202669 |
| visible | 1 |