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Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases

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Resumo:Introduction: Acute liver failure is an uncommon condition associated with a high mortality. Most patients do not survive without liver transplantation. In the last decades, auxiliary liver transplantation has emerged as a therapeutic option. Clinical Case: The authors present two cases of acute liver failure that required liver transplantation. Given the patients’ young age and the preserved macroscopic liver pattern evaluated in surgery, auxiliary liver transplantation was executed using different surgical approaches. Afterwards, following confirmed full native liver regeneration, the patients were submitted to auxiliary liver hepatectomy, which was accomplished without complications. Conclusion: Auxiliary liver transplantation can be regarded as an effective temporary treatment for acute liver failure in selected cases, allowing an immunosuppression-free life.
Autores principais:Perdigoto,David N.
Outros Autores:Tomé,Luís; Diogo,Dulce; Ferrão,José; Martins,Ricardo; Oliveira,Pedro; Tralhão,Guilherme; Furtado,Emanuel
Assunto:Acute liver failure Liver transplantation Auxiliary liver transplantation Immunosuppression
Ano:2019
País:Portugal
Tipo de documento:relatório
Tipo de acesso:acesso aberto
Instituição associada:Fundação para a Ciência e Tecnologia
Idioma:inglês
Origem:SciELO Portugal
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author Perdigoto,David N.
author2 Tomé,Luís
Diogo,Dulce
Ferrão,José
Martins,Ricardo
Oliveira,Pedro
Tralhão,Guilherme
Furtado,Emanuel
author2_role author
author
author
author
author
author
author
author_facet Perdigoto,David N.
Tomé,Luís
Diogo,Dulce
Ferrão,José
Martins,Ricardo
Oliveira,Pedro
Tralhão,Guilherme
Furtado,Emanuel
author_role author
country_str PT
creators_json_txt [{\"Person.name\":\"Perdigoto,David N.\"},{\"Person.name\":\"Tomé,Luís\"},{\"Person.name\":\"Diogo,Dulce\"},{\"Person.name\":\"Ferrão,José\"},{\"Person.name\":\"Martins,Ricardo\"},{\"Person.name\":\"Oliveira,Pedro\"},{\"Person.name\":\"Tralhão,Guilherme\"},{\"Person.name\":\"Furtado,Emanuel\"}]
datacite.creators.creator.creatorName.fl_str_mv Perdigoto,David N.
Tomé,Luís
Diogo,Dulce
Ferrão,José
Martins,Ricardo
Oliveira,Pedro
Tralhão,Guilherme
Furtado,Emanuel
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Acute liver failure
Liver transplantation
Auxiliary liver transplantation
Immunosuppression
datacite.titles.title.fl_str_mv Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases
dc.creator.none.fl_str_mv Perdigoto,David N.
Tomé,Luís
Diogo,Dulce
Ferrão,José
Martins,Ricardo
Oliveira,Pedro
Tralhão,Guilherme
Furtado,Emanuel
dc.format.none.fl_str_mv text/html
dc.identifier.none.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452019000100008
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Gastrenterologia
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.source.none.fl_str_mv GE-Portuguese Journal of Gastroenterology v.26 n.1 2019
dc.subject.none.fl_str_mv Acute liver failure
Liver transplantation
Auxiliary liver transplantation
Immunosuppression
dc.title.fl_str_mv Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_93fc
description Introduction: Acute liver failure is an uncommon condition associated with a high mortality. Most patients do not survive without liver transplantation. In the last decades, auxiliary liver transplantation has emerged as a therapeutic option. Clinical Case: The authors present two cases of acute liver failure that required liver transplantation. Given the patients’ young age and the preserved macroscopic liver pattern evaluated in surgery, auxiliary liver transplantation was executed using different surgical approaches. Afterwards, following confirmed full native liver regeneration, the patients were submitted to auxiliary liver hepatectomy, which was accomplished without complications. Conclusion: Auxiliary liver transplantation can be regarded as an effective temporary treatment for acute liver failure in selected cases, allowing an immunosuppression-free life.
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institution Fundação para a Ciência e Tecnologia
instname_str Fundação para a Ciência e Tecnologia
language eng
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person_str_mv Perdigoto,David N.
Tomé,Luís
Diogo,Dulce
Ferrão,José
Martins,Ricardo
Oliveira,Pedro
Tralhão,Guilherme
Furtado,Emanuel
publishDate 2019
publisher.none.fl_str_mv Sociedade Portuguesa de Gastrenterologia
reponame_str SciELO Portugal
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spelling Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two CasesPerdigoto,David N.Tomé,LuísDiogo,DulceFerrão,JoséMartins,RicardoOliveira,PedroTralhão,GuilhermeFurtado,EmanuelAcute liver failureLiver transplantationAuxiliary liver transplantationImmunosuppressionopen accesshttp://purl.org/coar/access_right/c_abf2http://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452019000100008URLhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452019000100008URLHasVersion2019-02-01Introduction: Acute liver failure is an uncommon condition associated with a high mortality. Most patients do not survive without liver transplantation. In the last decades, auxiliary liver transplantation has emerged as a therapeutic option. Clinical Case: The authors present two cases of acute liver failure that required liver transplantation. Given the patients’ young age and the preserved macroscopic liver pattern evaluated in surgery, auxiliary liver transplantation was executed using different surgical approaches. Afterwards, following confirmed full native liver regeneration, the patients were submitted to auxiliary liver hepatectomy, which was accomplished without complications. Conclusion: Auxiliary liver transplantation can be regarded as an effective temporary treatment for acute liver failure in selected cases, allowing an immunosuppression-free life.Sociedade Portuguesa de GastrenterologiaGE-Portuguese Journal of Gastroenterology v.26 n.1 2019text/htmlengreporthttp://purl.org/coar/resource_type/c_93fcother research product
spellingShingle Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases
Perdigoto,David N.
Acute liver failure
Liver transplantation
Auxiliary liver transplantation
Immunosuppression
status SINGLETON
subject.fl_str_mv Acute liver failure
Liver transplantation
Auxiliary liver transplantation
Immunosuppression
title Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases
title_full Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases
title_fullStr Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases
title_full_unstemmed Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases
title_short Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases
title_sort Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases
topic Acute liver failure
Liver transplantation
Auxiliary liver transplantation
Immunosuppression
topic_facet Acute liver failure
Liver transplantation
Auxiliary liver transplantation
Immunosuppression
url http://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452019000100008
visible 1