Detalhes bibliográficos
| Resumo: | ABSTRACT Operational tolerance in kidney transplantation is characterized by stable serum creatinine < 1.7 mg/dL and proteinuria < 1 g/day in the absence of immunosuppression or immunodeficiency for over one year. However, simultaneous donor specific antibodies are common and serum creatinine is a poor surrogate of early lesions. Consequently, subclinical rejections will meet operational tolerance criteria if sérum creatinine remains stable. We report a patient with operational tolerance criteria followed by biopsy-proven chronic active antibody mediated rejection, discussing the intricate challenges of immunosuppression management. |
|---|
| Autores principais: | Silva,Rui F. |
|---|
| Outros Autores: | Relvas,Miguel L.; Nunes,Ana; Silvano,José L.; Beco,Ana; Bustorff,Manuela B.; Sampaio,Susana M. |
|---|
| Assunto: | kidney transplantation operational tolerance antibody mediated rejection |
|---|
| Ano: | 2021 |
|---|
| País: | Portugal |
|---|
| Tipo de documento: | relatório |
|---|
| Tipo de acesso: | acesso aberto |
|---|
| Instituição associada: | Fundação para a Ciência e Tecnologia |
|---|
| Idioma: | português |
|---|
| Origem: | SciELO Portugal |
|---|