Publicação

The gray area between operational tolerance and overt rejection in kidney transplantation

Ver documento

Detalhes bibliográficos
Resumo:ABSTRACT Operational tolerance in kidney transplantation is characterized by stable serum creatinine < 1.7 mg/dL and proteinuria < 1 g/day in the absence of immunosuppression or immunodeficiency for over one year. However, simultaneous donor specific antibodies are common and serum creatinine is a poor surrogate of early lesions. Consequently, subclinical rejections will meet operational tolerance criteria if sérum creatinine remains stable. We report a patient with operational tolerance criteria followed by biopsy-proven chronic active antibody mediated rejection, discussing the intricate challenges of immunosuppression management.
Autores principais:Silva,Rui F.
Outros Autores:Relvas,Miguel L.; Nunes,Ana; Silvano,José L.; Beco,Ana; Bustorff,Manuela B.; Sampaio,Susana M.
Assunto:kidney transplantation operational tolerance antibody mediated rejection
Ano:2021
País:Portugal
Tipo de documento:relatório
Tipo de acesso:acesso aberto
Instituição associada:Fundação para a Ciência e Tecnologia
Idioma:português
Origem:SciELO Portugal

Registos relacionados

Registos relacionados