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Hepatic glycogen levels in female rats submitted to aquatic therapy after muscle disuse

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Resumo:The aim of the present study was to analyse the changes in liver glycogen content in rats subjected to aquatic therapy post-disuse of the paw. 32 wistar adult female rats were equally divided: Control (C), kept in the cage for two weeks without interventions; Disuse (D) had the right paw immobilized with hip extension, knee and plantar flexion for two weeks; Aquatic Therapy (AT) underwent aquatic therapy with increments of 3 minutes daily for two weeks, totalizing 36 minutes of training; Disused Aquatic Therapy (DTA) was first subjected to immobilization for two weeks and 24 hours after withdrawal of immobilization aquatic therapy was started for two more weeks, in same protocols of D and AT groups. At the end of the experiment, the animals were sacrificed, and tissues were dissected, weighed and stored. The liver tissues were referred analysis of glycogen content. It was observed that the blood glucose levels of the AT group (104 mg/dL) were different from the C group (86 mg/dL; p = 0.0213). Regarding hepatic glycogen, the D (2.35mg±0.07) and AT (2.73mg±0.07) groups had hepatic glycogen reduction by 22% and 15%, relative to C (2.51mg±0.03); p <0.0001). The DTA group presented no differences when compared to the control, suggesting the normalization of the finding. Muscle disuse by two weeks promoted changes in glycogen levels, however, two weeks after disuse condition, the aquatic therapy were able to correct the energetic reserve in liver.
Autores principais:Fortes,Jefferson Pacheco Amaral
Outros Autores:Carvalho,Felipe Lima de; Alves,Juliana Osório; Chaves,Marcia Maria Gonçalves Felinto; Carneiro,Mayara Rangel Araújo; Souza,Karla Camila Lima de; Júnior,Francisco Fleury Uchoa Santos; Ceccatto,Vânia Marilande
Assunto:Metabolism Immobilization Glycogen Muscle Liver
Ano:2017
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Fundação para a Ciência e Tecnologia
Idioma:inglês
Origem:SciELO Portugal
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author Fortes,Jefferson Pacheco Amaral
author2 Carvalho,Felipe Lima de
Alves,Juliana Osório
Chaves,Marcia Maria Gonçalves Felinto
Carneiro,Mayara Rangel Araújo
Souza,Karla Camila Lima de
Júnior,Francisco Fleury Uchoa Santos
Ceccatto,Vânia Marilande
author2_role author
author
author
author
author
author
author
author_facet Fortes,Jefferson Pacheco Amaral
Carvalho,Felipe Lima de
Alves,Juliana Osório
Chaves,Marcia Maria Gonçalves Felinto
Carneiro,Mayara Rangel Araújo
Souza,Karla Camila Lima de
Júnior,Francisco Fleury Uchoa Santos
Ceccatto,Vânia Marilande
author_role author
country_str PT
creators_json_txt [{\"Person.name\":\"Fortes,Jefferson Pacheco Amaral\"},{\"Person.name\":\"Carvalho,Felipe Lima de\"},{\"Person.name\":\"Alves,Juliana Osório\"},{\"Person.name\":\"Chaves,Marcia Maria Gonçalves Felinto\"},{\"Person.name\":\"Carneiro,Mayara Rangel Araújo\"},{\"Person.name\":\"Souza,Karla Camila Lima de\"},{\"Person.name\":\"Júnior,Francisco Fleury Uchoa Santos\"},{\"Person.name\":\"Ceccatto,Vânia Marilande\"}]
datacite.creators.creator.creatorName.fl_str_mv Fortes,Jefferson Pacheco Amaral
Carvalho,Felipe Lima de
Alves,Juliana Osório
Chaves,Marcia Maria Gonçalves Felinto
Carneiro,Mayara Rangel Araújo
Souza,Karla Camila Lima de
Júnior,Francisco Fleury Uchoa Santos
Ceccatto,Vânia Marilande
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Metabolism
Immobilization
Glycogen
Muscle
Liver
datacite.titles.title.fl_str_mv Hepatic glycogen levels in female rats submitted to aquatic therapy after muscle disuse
dc.creator.none.fl_str_mv Fortes,Jefferson Pacheco Amaral
Carvalho,Felipe Lima de
Alves,Juliana Osório
Chaves,Marcia Maria Gonçalves Felinto
Carneiro,Mayara Rangel Araújo
Souza,Karla Camila Lima de
Júnior,Francisco Fleury Uchoa Santos
Ceccatto,Vânia Marilande
dc.format.none.fl_str_mv text/html
dc.identifier.none.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-107X2017000400007
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Edições Desafio Singular
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.source.none.fl_str_mv Motricidade v.13 n.3 2017
dc.subject.none.fl_str_mv Metabolism
Immobilization
Glycogen
Muscle
Liver
dc.title.fl_str_mv Hepatic glycogen levels in female rats submitted to aquatic therapy after muscle disuse
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description The aim of the present study was to analyse the changes in liver glycogen content in rats subjected to aquatic therapy post-disuse of the paw. 32 wistar adult female rats were equally divided: Control (C), kept in the cage for two weeks without interventions; Disuse (D) had the right paw immobilized with hip extension, knee and plantar flexion for two weeks; Aquatic Therapy (AT) underwent aquatic therapy with increments of 3 minutes daily for two weeks, totalizing 36 minutes of training; Disused Aquatic Therapy (DTA) was first subjected to immobilization for two weeks and 24 hours after withdrawal of immobilization aquatic therapy was started for two more weeks, in same protocols of D and AT groups. At the end of the experiment, the animals were sacrificed, and tissues were dissected, weighed and stored. The liver tissues were referred analysis of glycogen content. It was observed that the blood glucose levels of the AT group (104 mg/dL) were different from the C group (86 mg/dL; p = 0.0213). Regarding hepatic glycogen, the D (2.35mg±0.07) and AT (2.73mg±0.07) groups had hepatic glycogen reduction by 22% and 15%, relative to C (2.51mg±0.03); p <0.0001). The DTA group presented no differences when compared to the control, suggesting the normalization of the finding. Muscle disuse by two weeks promoted changes in glycogen levels, however, two weeks after disuse condition, the aquatic therapy were able to correct the energetic reserve in liver.
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person_str_mv Fortes,Jefferson Pacheco Amaral
Carvalho,Felipe Lima de
Alves,Juliana Osório
Chaves,Marcia Maria Gonçalves Felinto
Carneiro,Mayara Rangel Araújo
Souza,Karla Camila Lima de
Júnior,Francisco Fleury Uchoa Santos
Ceccatto,Vânia Marilande
publishDate 2017
publisher.none.fl_str_mv Edições Desafio Singular
reponame_str SciELO Portugal
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spelling Hepatic glycogen levels in female rats submitted to aquatic therapy after muscle disuseFortes,Jefferson Pacheco AmaralCarvalho,Felipe Lima deAlves,Juliana OsórioChaves,Marcia Maria Gonçalves FelintoCarneiro,Mayara Rangel AraújoSouza,Karla Camila Lima deJúnior,Francisco Fleury Uchoa SantosCeccatto,Vânia MarilandeMetabolismImmobilizationGlycogenMuscleLiveropen accesshttp://purl.org/coar/access_right/c_abf2http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-107X2017000400007URLhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-107X2017000400007URLHasVersion2017-09-01The aim of the present study was to analyse the changes in liver glycogen content in rats subjected to aquatic therapy post-disuse of the paw. 32 wistar adult female rats were equally divided: Control (C), kept in the cage for two weeks without interventions; Disuse (D) had the right paw immobilized with hip extension, knee and plantar flexion for two weeks; Aquatic Therapy (AT) underwent aquatic therapy with increments of 3 minutes daily for two weeks, totalizing 36 minutes of training; Disused Aquatic Therapy (DTA) was first subjected to immobilization for two weeks and 24 hours after withdrawal of immobilization aquatic therapy was started for two more weeks, in same protocols of D and AT groups. At the end of the experiment, the animals were sacrificed, and tissues were dissected, weighed and stored. The liver tissues were referred analysis of glycogen content. It was observed that the blood glucose levels of the AT group (104 mg/dL) were different from the C group (86 mg/dL; p = 0.0213). Regarding hepatic glycogen, the D (2.35mg±0.07) and AT (2.73mg±0.07) groups had hepatic glycogen reduction by 22% and 15%, relative to C (2.51mg±0.03); p <0.0001). The DTA group presented no differences when compared to the control, suggesting the normalization of the finding. Muscle disuse by two weeks promoted changes in glycogen levels, however, two weeks after disuse condition, the aquatic therapy were able to correct the energetic reserve in liver.Edições Desafio SingularMotricidade v.13 n.3 2017text/htmlengjournal articlehttp://purl.org/coar/resource_type/c_6501literature
spellingShingle Hepatic glycogen levels in female rats submitted to aquatic therapy after muscle disuse
Fortes,Jefferson Pacheco Amaral
Metabolism
Immobilization
Glycogen
Muscle
Liver
status SINGLETON
subject.fl_str_mv Metabolism
Immobilization
Glycogen
Muscle
Liver
title Hepatic glycogen levels in female rats submitted to aquatic therapy after muscle disuse
title_full Hepatic glycogen levels in female rats submitted to aquatic therapy after muscle disuse
title_fullStr Hepatic glycogen levels in female rats submitted to aquatic therapy after muscle disuse
title_full_unstemmed Hepatic glycogen levels in female rats submitted to aquatic therapy after muscle disuse
title_short Hepatic glycogen levels in female rats submitted to aquatic therapy after muscle disuse
title_sort Hepatic glycogen levels in female rats submitted to aquatic therapy after muscle disuse
topic Metabolism
Immobilization
Glycogen
Muscle
Liver
topic_facet Metabolism
Immobilization
Glycogen
Muscle
Liver
url http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-107X2017000400007
visible 1