Publicação
Antiphospholipid syndrome
| Resumo: | The antiphospholipid syndrome (APS) is defined by the development of venous and/or arterial thromboses, often multiple, and pregnancy morbidity (mainly, recurrent fetal losses), in the presence of antiphospholipid antibodies (aPL). Some estimates indicate that the incidence of the APS is around 5 new cases per 100 000 persons per year and the prevalence around 40-50 cases per 100 000 persons. The aPL are positive in approximately 13% of patients with stroke, 11% with myocardial infarction, 9.5% of patients with deep vein thrombosis and 6% of patients with pregnancy morbidity. Currently, there is consensus in treating APS patients with thrombosis with long-term oral anticoagulation and to prevent obstetric manifestations with the use of aspirin and heparin. This review summarizes the main knowledge on the clinical and therapeutic aspects of this syndrome |
|---|---|
| Autores principais: | Cervera,Ricard |
| Outros Autores: | Espinosa,Gerard |
| Assunto: | Antibodies Anticardiolipin Antibodies Antiphospholipid Antiphospholipid Syndrome Stroke |
| Ano: | 2018 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Fundação para a Ciência e Tecnologia |
| Idioma: | inglês |
| Origem: | SciELO Portugal |
| _version_ | 1868441724575023104 |
|---|---|
| author | Cervera,Ricard |
| author2 | Espinosa,Gerard |
| author2_role | author |
| author_facet | Cervera,Ricard Espinosa,Gerard |
| author_role | author |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Cervera,Ricard\"},{\"Person.name\":\"Espinosa,Gerard\"}] |
| datacite.creators.creator.creatorName.fl_str_mv | Cervera,Ricard Espinosa,Gerard |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Antibodies Anticardiolipin Antibodies Antiphospholipid Antiphospholipid Syndrome Stroke |
| datacite.titles.title.fl_str_mv | Antiphospholipid syndrome |
| dc.creator.none.fl_str_mv | Cervera,Ricard Espinosa,Gerard |
| dc.format.none.fl_str_mv | text/html |
| dc.identifier.none.fl_str_mv | http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-671X2018000400013 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Sociedade Portuguesa de Medicina Interna |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.source.none.fl_str_mv | Medicina Interna v.25 n.4 2018 |
| dc.subject.none.fl_str_mv | Antibodies Anticardiolipin Antibodies Antiphospholipid Antiphospholipid Syndrome Stroke |
| dc.title.fl_str_mv | Antiphospholipid syndrome |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | The antiphospholipid syndrome (APS) is defined by the development of venous and/or arterial thromboses, often multiple, and pregnancy morbidity (mainly, recurrent fetal losses), in the presence of antiphospholipid antibodies (aPL). Some estimates indicate that the incidence of the APS is around 5 new cases per 100 000 persons per year and the prevalence around 40-50 cases per 100 000 persons. The aPL are positive in approximately 13% of patients with stroke, 11% with myocardial infarction, 9.5% of patients with deep vein thrombosis and 6% of patients with pregnancy morbidity. Currently, there is consensus in treating APS patients with thrombosis with long-term oral anticoagulation and to prevent obstetric manifestations with the use of aspirin and heparin. This review summarizes the main knowledge on the clinical and therapeutic aspects of this syndrome |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| id | scielopt_4160cd9109813d2c8b77fba81b3a2dfd |
| identifier.url.fl_str_mv | http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-671X2018000400013 |
| instacron_str | SciELO |
| institution | Fundação para a Ciência e Tecnologia |
| instname_str | Fundação para a Ciência e Tecnologia |
| language | eng |
| network_acronym_str | scielopt |
| network_name_str | SciELO Portugal |
| oai_identifier_str | oai:scielo:S0872-671X2018000400013 |
| organization_str_mv | urn:organizationAcronym:scielo |
| person_str_mv | Cervera,Ricard Espinosa,Gerard |
| publishDate | 2018 |
| publisher.none.fl_str_mv | Sociedade Portuguesa de Medicina Interna |
| reponame_str | SciELO Portugal |
| repository_id_str | urn:repositoryAcronym:scielopt |
| service_str_mv | urn:repositoryAcronym:scielopt |
| spelling | Antiphospholipid syndromeCervera,RicardEspinosa,GerardAntibodiesAnticardiolipinAntibodiesAntiphospholipidAntiphospholipid SyndromeStrokeopen accesshttp://purl.org/coar/access_right/c_abf2http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-671X2018000400013URLhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-671X2018000400013URLHasVersion2018-12-01The antiphospholipid syndrome (APS) is defined by the development of venous and/or arterial thromboses, often multiple, and pregnancy morbidity (mainly, recurrent fetal losses), in the presence of antiphospholipid antibodies (aPL). Some estimates indicate that the incidence of the APS is around 5 new cases per 100 000 persons per year and the prevalence around 40-50 cases per 100 000 persons. The aPL are positive in approximately 13% of patients with stroke, 11% with myocardial infarction, 9.5% of patients with deep vein thrombosis and 6% of patients with pregnancy morbidity. Currently, there is consensus in treating APS patients with thrombosis with long-term oral anticoagulation and to prevent obstetric manifestations with the use of aspirin and heparin. This review summarizes the main knowledge on the clinical and therapeutic aspects of this syndromeSociedade Portuguesa de Medicina InternaMedicina Interna v.25 n.4 2018text/htmlengjournal articlehttp://purl.org/coar/resource_type/c_6501literature |
| spellingShingle | Antiphospholipid syndrome Cervera,Ricard Antibodies Anticardiolipin Antibodies Antiphospholipid Antiphospholipid Syndrome Stroke |
| status | SINGLETON |
| subject.fl_str_mv | Antibodies Anticardiolipin Antibodies Antiphospholipid Antiphospholipid Syndrome Stroke |
| title | Antiphospholipid syndrome |
| title_full | Antiphospholipid syndrome |
| title_fullStr | Antiphospholipid syndrome |
| title_full_unstemmed | Antiphospholipid syndrome |
| title_short | Antiphospholipid syndrome |
| title_sort | Antiphospholipid syndrome |
| topic | Antibodies Anticardiolipin Antibodies Antiphospholipid Antiphospholipid Syndrome Stroke |
| topic_facet | Antibodies Anticardiolipin Antibodies Antiphospholipid Antiphospholipid Syndrome Stroke |
| url | http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-671X2018000400013 |
| visible | 1 |