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A literature review on pharmacologic therapy for abdominal aortic aneurysms

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Resumo:Abstract Introduction: Aortic aneurysms affect 3.3% of adults and there is a growing burden of small aneurysms detected, which may grow to need surgical repair. Still, we rely only on surgical therapy for this disease, left to monitor patients until they are candidates for treatment. Pharmacologic therapies have long been proposed and studied and still we have no evidence supporting drug therapy in small aneurysms. In this report we make a narrative review of basic molecular aspects of aneurysm disease and of evidence behind drug therapies that have been proposed and studied throughout the last decades.
Autores principais:Rodrigues,Marta Romão
Outros Autores:Melo,Ryan Gouveia e; Silvestre,Luís; Fernandes,Ruy Fernandes e; Martins,Carlos; Pedro,Luís Mendes
Assunto:aneurysm aorta pharmacology therapy
Ano:2023
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Fundação para a Ciência e Tecnologia
Idioma:inglês
Origem:SciELO Portugal
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author Rodrigues,Marta Romão
author2 Melo,Ryan Gouveia e
Silvestre,Luís
Fernandes,Ruy Fernandes e
Martins,Carlos
Pedro,Luís Mendes
author2_role author
author
author
author
author
author_facet Rodrigues,Marta Romão
Melo,Ryan Gouveia e
Silvestre,Luís
Fernandes,Ruy Fernandes e
Martins,Carlos
Pedro,Luís Mendes
author_role author
country_str PT
creators_json_txt [{\"Person.name\":\"Rodrigues,Marta Romão\"},{\"Person.name\":\"Melo,Ryan Gouveia e\"},{\"Person.name\":\"Silvestre,Luís\"},{\"Person.name\":\"Fernandes,Ruy Fernandes e\"},{\"Person.name\":\"Martins,Carlos\"},{\"Person.name\":\"Pedro,Luís Mendes\"}]
datacite.creators.creator.creatorName.fl_str_mv Rodrigues,Marta Romão
Melo,Ryan Gouveia e
Silvestre,Luís
Fernandes,Ruy Fernandes e
Martins,Carlos
Pedro,Luís Mendes
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv aneurysm
aorta
pharmacology
therapy
datacite.titles.title.fl_str_mv A literature review on pharmacologic therapy for abdominal aortic aneurysms
dc.creator.none.fl_str_mv Rodrigues,Marta Romão
Melo,Ryan Gouveia e
Silvestre,Luís
Fernandes,Ruy Fernandes e
Martins,Carlos
Pedro,Luís Mendes
dc.format.none.fl_str_mv text/html
dc.identifier.none.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-706X2023000100044
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Angiologia e Cirurgia Vascular
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.source.none.fl_str_mv Angiologia e Cirurgia Vascular v.19 n.1 2023
dc.subject.none.fl_str_mv aneurysm
aorta
pharmacology
therapy
dc.title.fl_str_mv A literature review on pharmacologic therapy for abdominal aortic aneurysms
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description Abstract Introduction: Aortic aneurysms affect 3.3% of adults and there is a growing burden of small aneurysms detected, which may grow to need surgical repair. Still, we rely only on surgical therapy for this disease, left to monitor patients until they are candidates for treatment. Pharmacologic therapies have long been proposed and studied and still we have no evidence supporting drug therapy in small aneurysms. In this report we make a narrative review of basic molecular aspects of aneurysm disease and of evidence behind drug therapies that have been proposed and studied throughout the last decades.
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identifier.url.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-706X2023000100044
instacron_str SciELO
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oai_identifier_str oai:scielo:S1646-706X2023000100044
organization_str_mv urn:organizationAcronym:scielo
person_str_mv Rodrigues,Marta Romão
Melo,Ryan Gouveia e
Silvestre,Luís
Fernandes,Ruy Fernandes e
Martins,Carlos
Pedro,Luís Mendes
publishDate 2023
publisher.none.fl_str_mv Sociedade Portuguesa de Angiologia e Cirurgia Vascular
reponame_str SciELO Portugal
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spelling A literature review on pharmacologic therapy for abdominal aortic aneurysmsRodrigues,Marta RomãoMelo,Ryan Gouveia eSilvestre,LuísFernandes,Ruy Fernandes eMartins,CarlosPedro,Luís Mendesaneurysmaortapharmacologytherapyopen accesshttp://purl.org/coar/access_right/c_abf2http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-706X2023000100044URLhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-706X2023000100044URLHasVersion2023-03-01Abstract Introduction: Aortic aneurysms affect 3.3% of adults and there is a growing burden of small aneurysms detected, which may grow to need surgical repair. Still, we rely only on surgical therapy for this disease, left to monitor patients until they are candidates for treatment. Pharmacologic therapies have long been proposed and studied and still we have no evidence supporting drug therapy in small aneurysms. In this report we make a narrative review of basic molecular aspects of aneurysm disease and of evidence behind drug therapies that have been proposed and studied throughout the last decades.Sociedade Portuguesa de Angiologia e Cirurgia VascularAngiologia e Cirurgia Vascular v.19 n.1 2023text/htmlengjournal articlehttp://purl.org/coar/resource_type/c_6501literature
spellingShingle A literature review on pharmacologic therapy for abdominal aortic aneurysms
Rodrigues,Marta Romão
aneurysm
aorta
pharmacology
therapy
status SINGLETON
subject.fl_str_mv aneurysm
aorta
pharmacology
therapy
title A literature review on pharmacologic therapy for abdominal aortic aneurysms
title_full A literature review on pharmacologic therapy for abdominal aortic aneurysms
title_fullStr A literature review on pharmacologic therapy for abdominal aortic aneurysms
title_full_unstemmed A literature review on pharmacologic therapy for abdominal aortic aneurysms
title_short A literature review on pharmacologic therapy for abdominal aortic aneurysms
title_sort A literature review on pharmacologic therapy for abdominal aortic aneurysms
topic aneurysm
aorta
pharmacology
therapy
topic_facet aneurysm
aorta
pharmacology
therapy
url http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-706X2023000100044
visible 1