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Tofacitinib: An Option for Acute Severe Ulcerative Colitis?

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Resumo:Abstract Tofacitinib has emerged as a new option for ulcerative colitis. Its rapid absorption, metabolism, and clinical improvement make it an interesting option for rescue therapy in acute severe ulcerative colitis (ASUC), a situation with limited therapeutic options in patients with a long-term disease course and multiple drug failure. The management of ASUC in this setting becomes challenging, underlying the need for new drugs and data on their efficacy and safety. We describe 2 cases of acute episodes in which tofacitinib was used as a rescue therapy.
Autores principais:Santos,Sara
Outros Autores:Gamelas,Verónica; Saraiva,Rita; Simões,Guilherme; Saiote,Joana; Ramos,Jaime
Assunto:Acute severe ulcerative colitis Tofacitinib
Ano:2022
País:Portugal
Tipo de documento:relatório
Tipo de acesso:acesso aberto
Instituição associada:Fundação para a Ciência e Tecnologia
Idioma:inglês
Origem:SciELO Portugal

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