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Cathodic Stripping Voltammetric Determination of Losartan in Bulk and Pharmaceutical Products
| Resumo: | Cathodic stripping voltammetric determination of losartan using hanging mercury drop electrode HMDE was described. The method was based on adsorptive accumulation of the species at HMDE and at pH 7, followed by alternating current AC sweep. The behavior of adsorptive stripping response was studied under various experimental conditions, e.g. type of supporting electrolyte, pH, accumulation time, scan rate and mode of sweep (direct current DC, differential pulse DP, square wave SW and AC). In Britton-Robinson buffer solution, pH 7, a quasi-reversible reaction took place. The reduction response was more sensitive than the oxidation one and it was linear over the concentration range of 0.16-1.2 mg/mL. The determination of the cited compound in oral dosages was achieved using the standard addition method. The average of determinations obtained by square wave adsorptive voltammetric method with its standard deviation was 100.1±3%. |
|---|---|
| Autores principais: | Habib,I.H.I. |
| Outros Autores: | Weshahy,S.A.; Toubar,S.; El-Alamin,M.M.A. |
| Assunto: | losartan adsorptive stripping voltammetry HMDE stability |
| Ano: | 2008 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Fundação para a Ciência e Tecnologia |
| Idioma: | inglês |
| Origem: | SciELO Portugal |
| _version_ | 1868441710827143168 |
|---|---|
| author | Habib,I.H.I. |
| author2 | Weshahy,S.A. Toubar,S. El-Alamin,M.M.A. |
| author2_role | author author author |
| author_facet | Habib,I.H.I. Weshahy,S.A. Toubar,S. El-Alamin,M.M.A. |
| author_role | author |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Habib,I.H.I.\"},{\"Person.name\":\"Weshahy,S.A.\"},{\"Person.name\":\"Toubar,S.\"},{\"Person.name\":\"El-Alamin,M.M.A.\"}] |
| datacite.creators.creator.creatorName.fl_str_mv | Habib,I.H.I. Weshahy,S.A. Toubar,S. El-Alamin,M.M.A. |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | losartan adsorptive stripping voltammetry HMDE stability |
| datacite.titles.title.fl_str_mv | Cathodic Stripping Voltammetric Determination of Losartan in Bulk and Pharmaceutical Products |
| dc.creator.none.fl_str_mv | Habib,I.H.I. Weshahy,S.A. Toubar,S. El-Alamin,M.M.A. |
| dc.format.none.fl_str_mv | text/html |
| dc.identifier.none.fl_str_mv | http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042008000400001 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Sociedade Portuguesa de Electroquímica |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.source.none.fl_str_mv | Portugaliae Electrochimica Acta v.26 n.4 2008 |
| dc.subject.none.fl_str_mv | losartan adsorptive stripping voltammetry HMDE stability |
| dc.title.fl_str_mv | Cathodic Stripping Voltammetric Determination of Losartan in Bulk and Pharmaceutical Products |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Cathodic stripping voltammetric determination of losartan using hanging mercury drop electrode HMDE was described. The method was based on adsorptive accumulation of the species at HMDE and at pH 7, followed by alternating current AC sweep. The behavior of adsorptive stripping response was studied under various experimental conditions, e.g. type of supporting electrolyte, pH, accumulation time, scan rate and mode of sweep (direct current DC, differential pulse DP, square wave SW and AC). In Britton-Robinson buffer solution, pH 7, a quasi-reversible reaction took place. The reduction response was more sensitive than the oxidation one and it was linear over the concentration range of 0.16-1.2 mg/mL. The determination of the cited compound in oral dosages was achieved using the standard addition method. The average of determinations obtained by square wave adsorptive voltammetric method with its standard deviation was 100.1±3%. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| id | scielopt_8cc361b83db09e2022bd695cefa187fd |
| identifier.url.fl_str_mv | http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042008000400001 |
| instacron_str | SciELO |
| institution | Fundação para a Ciência e Tecnologia |
| instname_str | Fundação para a Ciência e Tecnologia |
| language | eng |
| network_acronym_str | scielopt |
| network_name_str | SciELO Portugal |
| oai_identifier_str | oai:scielo:S0872-19042008000400001 |
| organization_str_mv | urn:organizationAcronym:scielo |
| person_str_mv | Habib,I.H.I. Weshahy,S.A. Toubar,S. El-Alamin,M.M.A. |
| publishDate | 2008 |
| publisher.none.fl_str_mv | Sociedade Portuguesa de Electroquímica |
| reponame_str | SciELO Portugal |
| repository_id_str | urn:repositoryAcronym:scielopt |
| service_str_mv | urn:repositoryAcronym:scielopt |
| spelling | Cathodic Stripping Voltammetric Determination of Losartan in Bulk and Pharmaceutical ProductsHabib,I.H.I.Weshahy,S.A.Toubar,S.El-Alamin,M.M.A.losartanadsorptive stripping voltammetryHMDEstabilityopen accesshttp://purl.org/coar/access_right/c_abf2http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042008000400001URLhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042008000400001URLHasVersion2008-01-01Cathodic stripping voltammetric determination of losartan using hanging mercury drop electrode HMDE was described. The method was based on adsorptive accumulation of the species at HMDE and at pH 7, followed by alternating current AC sweep. The behavior of adsorptive stripping response was studied under various experimental conditions, e.g. type of supporting electrolyte, pH, accumulation time, scan rate and mode of sweep (direct current DC, differential pulse DP, square wave SW and AC). In Britton-Robinson buffer solution, pH 7, a quasi-reversible reaction took place. The reduction response was more sensitive than the oxidation one and it was linear over the concentration range of 0.16-1.2 mg/mL. The determination of the cited compound in oral dosages was achieved using the standard addition method. The average of determinations obtained by square wave adsorptive voltammetric method with its standard deviation was 100.1±3%.Sociedade Portuguesa de ElectroquímicaPortugaliae Electrochimica Acta v.26 n.4 2008text/htmlengjournal articlehttp://purl.org/coar/resource_type/c_6501literature |
| spellingShingle | Cathodic Stripping Voltammetric Determination of Losartan in Bulk and Pharmaceutical Products Habib,I.H.I. losartan adsorptive stripping voltammetry HMDE stability |
| status | SINGLETON |
| subject.fl_str_mv | losartan adsorptive stripping voltammetry HMDE stability |
| title | Cathodic Stripping Voltammetric Determination of Losartan in Bulk and Pharmaceutical Products |
| title_full | Cathodic Stripping Voltammetric Determination of Losartan in Bulk and Pharmaceutical Products |
| title_fullStr | Cathodic Stripping Voltammetric Determination of Losartan in Bulk and Pharmaceutical Products |
| title_full_unstemmed | Cathodic Stripping Voltammetric Determination of Losartan in Bulk and Pharmaceutical Products |
| title_short | Cathodic Stripping Voltammetric Determination of Losartan in Bulk and Pharmaceutical Products |
| title_sort | Cathodic Stripping Voltammetric Determination of Losartan in Bulk and Pharmaceutical Products |
| topic | losartan adsorptive stripping voltammetry HMDE stability |
| topic_facet | losartan adsorptive stripping voltammetry HMDE stability |
| url | http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-19042008000400001 |
| visible | 1 |