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Diagnosis Approach of Non-Hepatic Ascites: Peritoneal Mesothelioma

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Detalhes bibliográficos
Resumo:Abstract Malignant mesothelioma is a heterogeneous disease and peritoneal mesothelioma (PM) is an uncommon aetiology of non-hepatic ascites. Asbestos exposure is not directly associated with the disease progression and symptoms are non-specific, which delays the diagnosis. Radiology assessment and exploratory laparoscopy (with biopsy) are the main strategies to achieve and confirm PM diagnosis. Laparoscopy also plays an important role in staging. Due to its prevalence, few prospective trials or evidenced-based recommendations exist. Treatment options are often extrapolated from pleural mesothelioma. In this paper, the authors present an ascites diagnosis workup that leads to a PM. This case reflects the difficulty of the diagnosis.
Autores principais:Dias,Diogo Duarte
Outros Autores:Louro,Rita; Vieira,Ana Teresa; Amaro,Margarida; Escária,Susana Dias
Assunto:Ascites/diagnosis Mesothelioma, Malignant/diagnosis Peritoneal Neoplasms/diagnosis.
Ano:2025
País:Portugal
Tipo de documento:relatório
Tipo de acesso:acesso aberto
Instituição associada:Fundação para a Ciência e Tecnologia
Idioma:inglês
Origem:SciELO Portugal
Descrição
Resumo:Abstract Malignant mesothelioma is a heterogeneous disease and peritoneal mesothelioma (PM) is an uncommon aetiology of non-hepatic ascites. Asbestos exposure is not directly associated with the disease progression and symptoms are non-specific, which delays the diagnosis. Radiology assessment and exploratory laparoscopy (with biopsy) are the main strategies to achieve and confirm PM diagnosis. Laparoscopy also plays an important role in staging. Due to its prevalence, few prospective trials or evidenced-based recommendations exist. Treatment options are often extrapolated from pleural mesothelioma. In this paper, the authors present an ascites diagnosis workup that leads to a PM. This case reflects the difficulty of the diagnosis.