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The Importance of a Peritoneal Dialysis‑First Policy in Long Term Outcomes

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Resumo:Abstract Introduction: A significant part of peritoneal dialysis (PD) patients begins renal replacement therapy (RRT) through hemodialysis (HD) before transitioning to PD. We aim to evaluate the impact of an initial period on HD before transitioning to PD on the outcomes. Material and Methods: We conducted a retrospective cohort study including the prevalent PD patients between January 2017 and December 2019. Demographic and clinical data were collected at the time of PD start and one and two years after. Patients were divided in two groups, “PD‑first” group and “HD‑first” group, for comparison. Results: Seventy‑eight PD patients were included, mostly male (66.7%; n=52), with a mean age of 52.2±14.3 years. Thirty‑three patients (42.3%) initiated RRT with intermittent HD and switched to PD after a median time of 3 months. We found no difference between “HD‑first” and “PD‑first” groups regarding demographic data, prevalence of comorbidities or renal disease etiology. At the moment of PD start and one and two years later patients on the “HD‑first” had a significant lower volume of residual diuresis and of residual kidney function (RKF). At one and two‑years follow‑up “HD‑first” group also needed a higher number of antihypertensive drugs, had lower weekly Kt/V and a higher number of episodes of peritonitis. Patients in the “HD‑first” group also had significantly more cardiovascular events after two years. Conclusion: A period in HD prior to PD seems to precipitate a faster reduction of RKF and dialysis efficacy. We reinforce the importance of promoting the start of PD‑first and urgent‑start PD programs.
Autores principais:Correia,Ana Luísa
Outros Autores:Almiro e Castro,Pedro; Mira,Filipe; Cerqueira,Sofia; Marques,Maria Guedes; Maia,Pedro; Alves,Rui
Assunto:Hemodialysis, Home Kidney Failure, Chronic/therapy Outpatient Clinics, Hospital Peritoneal Dialysis Treatment Outcome
Ano:2024
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Fundação para a Ciência e Tecnologia
Idioma:inglês
Origem:SciELO Portugal
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author Correia,Ana Luísa
author2 Almiro e Castro,Pedro
Mira,Filipe
Cerqueira,Sofia
Marques,Maria Guedes
Maia,Pedro
Alves,Rui
author2_role author
author
author
author
author
author
author_facet Correia,Ana Luísa
Almiro e Castro,Pedro
Mira,Filipe
Cerqueira,Sofia
Marques,Maria Guedes
Maia,Pedro
Alves,Rui
author_role author
country_str PT
creators_json_txt [{\"Person.name\":\"Correia,Ana Luísa\"},{\"Person.name\":\"Almiro e Castro,Pedro\"},{\"Person.name\":\"Mira,Filipe\"},{\"Person.name\":\"Cerqueira,Sofia\"},{\"Person.name\":\"Marques,Maria Guedes\"},{\"Person.name\":\"Maia,Pedro\"},{\"Person.name\":\"Alves,Rui\"}]
datacite.creators.creator.creatorName.fl_str_mv Correia,Ana Luísa
Almiro e Castro,Pedro
Mira,Filipe
Cerqueira,Sofia
Marques,Maria Guedes
Maia,Pedro
Alves,Rui
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Hemodialysis, Home
Kidney Failure, Chronic/therapy
Outpatient Clinics, Hospital
Peritoneal Dialysis
Treatment Outcome
datacite.titles.title.fl_str_mv The Importance of a Peritoneal Dialysis‑First Policy in Long Term Outcomes
dc.creator.none.fl_str_mv Correia,Ana Luísa
Almiro e Castro,Pedro
Mira,Filipe
Cerqueira,Sofia
Marques,Maria Guedes
Maia,Pedro
Alves,Rui
dc.format.none.fl_str_mv text/html
dc.identifier.none.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S2976-05262024000100025
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Nefrologia
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.source.none.fl_str_mv Portuguese Kidney Journal (PKJ) v.38 n.1 2024
dc.subject.none.fl_str_mv Hemodialysis, Home
Kidney Failure, Chronic/therapy
Outpatient Clinics, Hospital
Peritoneal Dialysis
Treatment Outcome
dc.title.fl_str_mv The Importance of a Peritoneal Dialysis‑First Policy in Long Term Outcomes
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description Abstract Introduction: A significant part of peritoneal dialysis (PD) patients begins renal replacement therapy (RRT) through hemodialysis (HD) before transitioning to PD. We aim to evaluate the impact of an initial period on HD before transitioning to PD on the outcomes. Material and Methods: We conducted a retrospective cohort study including the prevalent PD patients between January 2017 and December 2019. Demographic and clinical data were collected at the time of PD start and one and two years after. Patients were divided in two groups, “PD‑first” group and “HD‑first” group, for comparison. Results: Seventy‑eight PD patients were included, mostly male (66.7%; n=52), with a mean age of 52.2±14.3 years. Thirty‑three patients (42.3%) initiated RRT with intermittent HD and switched to PD after a median time of 3 months. We found no difference between “HD‑first” and “PD‑first” groups regarding demographic data, prevalence of comorbidities or renal disease etiology. At the moment of PD start and one and two years later patients on the “HD‑first” had a significant lower volume of residual diuresis and of residual kidney function (RKF). At one and two‑years follow‑up “HD‑first” group also needed a higher number of antihypertensive drugs, had lower weekly Kt/V and a higher number of episodes of peritonitis. Patients in the “HD‑first” group also had significantly more cardiovascular events after two years. Conclusion: A period in HD prior to PD seems to precipitate a faster reduction of RKF and dialysis efficacy. We reinforce the importance of promoting the start of PD‑first and urgent‑start PD programs.
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person_str_mv Correia,Ana Luísa
Almiro e Castro,Pedro
Mira,Filipe
Cerqueira,Sofia
Marques,Maria Guedes
Maia,Pedro
Alves,Rui
publishDate 2024
publisher.none.fl_str_mv Sociedade Portuguesa de Nefrologia
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spelling The Importance of a Peritoneal Dialysis‑First Policy in Long Term OutcomesCorreia,Ana LuísaAlmiro e Castro,PedroMira,FilipeCerqueira,SofiaMarques,Maria GuedesMaia,PedroAlves,RuiHemodialysis, HomeKidney Failure, Chronic/therapyOutpatient Clinics, HospitalPeritoneal DialysisTreatment Outcomeopen accesshttp://purl.org/coar/access_right/c_abf2http://scielo.pt/scielo.php?script=sci_arttext&pid=S2976-05262024000100025URLhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S2976-05262024000100025URLHasVersion2024-03-01Abstract Introduction: A significant part of peritoneal dialysis (PD) patients begins renal replacement therapy (RRT) through hemodialysis (HD) before transitioning to PD. We aim to evaluate the impact of an initial period on HD before transitioning to PD on the outcomes. Material and Methods: We conducted a retrospective cohort study including the prevalent PD patients between January 2017 and December 2019. Demographic and clinical data were collected at the time of PD start and one and two years after. Patients were divided in two groups, “PD‑first” group and “HD‑first” group, for comparison. Results: Seventy‑eight PD patients were included, mostly male (66.7%; n=52), with a mean age of 52.2±14.3 years. Thirty‑three patients (42.3%) initiated RRT with intermittent HD and switched to PD after a median time of 3 months. We found no difference between “HD‑first” and “PD‑first” groups regarding demographic data, prevalence of comorbidities or renal disease etiology. At the moment of PD start and one and two years later patients on the “HD‑first” had a significant lower volume of residual diuresis and of residual kidney function (RKF). At one and two‑years follow‑up “HD‑first” group also needed a higher number of antihypertensive drugs, had lower weekly Kt/V and a higher number of episodes of peritonitis. Patients in the “HD‑first” group also had significantly more cardiovascular events after two years. Conclusion: A period in HD prior to PD seems to precipitate a faster reduction of RKF and dialysis efficacy. We reinforce the importance of promoting the start of PD‑first and urgent‑start PD programs.Sociedade Portuguesa de NefrologiaPortuguese Kidney Journal (PKJ) v.38 n.1 2024text/htmlengjournal articlehttp://purl.org/coar/resource_type/c_6501literature
spellingShingle The Importance of a Peritoneal Dialysis‑First Policy in Long Term Outcomes
Correia,Ana Luísa
Hemodialysis, Home
Kidney Failure, Chronic/therapy
Outpatient Clinics, Hospital
Peritoneal Dialysis
Treatment Outcome
status SINGLETON
subject.fl_str_mv Hemodialysis, Home
Kidney Failure, Chronic/therapy
Outpatient Clinics, Hospital
Peritoneal Dialysis
Treatment Outcome
title The Importance of a Peritoneal Dialysis‑First Policy in Long Term Outcomes
title_full The Importance of a Peritoneal Dialysis‑First Policy in Long Term Outcomes
title_fullStr The Importance of a Peritoneal Dialysis‑First Policy in Long Term Outcomes
title_full_unstemmed The Importance of a Peritoneal Dialysis‑First Policy in Long Term Outcomes
title_short The Importance of a Peritoneal Dialysis‑First Policy in Long Term Outcomes
title_sort The Importance of a Peritoneal Dialysis‑First Policy in Long Term Outcomes
topic Hemodialysis, Home
Kidney Failure, Chronic/therapy
Outpatient Clinics, Hospital
Peritoneal Dialysis
Treatment Outcome
topic_facet Hemodialysis, Home
Kidney Failure, Chronic/therapy
Outpatient Clinics, Hospital
Peritoneal Dialysis
Treatment Outcome
url http://scielo.pt/scielo.php?script=sci_arttext&pid=S2976-05262024000100025
visible 1