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Cutaneous pathergy and squamous cell carcinoma: a report of two cases

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Resumo:Abstract Cutaneous pathergy is a phenomenon demonstrating an exaggerated wound response following minor trauma. While often associated with inflammatory conditions, its association with carcinogenesis is less often described. Recognition of this important phenomenon may be challenging to clinicians who do not encounter it regularly. Cutaneous pathergic squamous cell carcinomas (SCCs) most typically occur as numerous eruptive neoplasms in female patients in sites of trauma or in the background of lichen simplex chronicus or lichenoid dermatoses. Management can be difficult and is typically non-surgical. Herein, we describe two cases of pathergic SCCs and our approach to treatment.
Autores principais:Miller,Austinn C.
Outros Autores:Bhate,Chinmoy; Constantinescu,Monica; Gregory,Julianna; Cognetta Jr.,Armand B.
Assunto:Pathergy Cutaneous squamous cell carcinoma Fluorouracil Retinoid
Ano:2025
País:Portugal
Tipo de documento:relatório
Tipo de acesso:acesso aberto
Instituição associada:Fundação para a Ciência e Tecnologia
Idioma:inglês
Origem:SciELO Portugal
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author Miller,Austinn C.
author2 Bhate,Chinmoy
Constantinescu,Monica
Gregory,Julianna
Cognetta Jr.,Armand B.
author2_role author
author
author
author
author_facet Miller,Austinn C.
Bhate,Chinmoy
Constantinescu,Monica
Gregory,Julianna
Cognetta Jr.,Armand B.
author_role author
country_str PT
creators_json_txt [{\"Person.name\":\"Miller,Austinn C.\"},{\"Person.name\":\"Bhate,Chinmoy\"},{\"Person.name\":\"Constantinescu,Monica\"},{\"Person.name\":\"Gregory,Julianna\"},{\"Person.name\":\"Cognetta Jr.,Armand B.\"}]
datacite.creators.creator.creatorName.fl_str_mv Miller,Austinn C.
Bhate,Chinmoy
Constantinescu,Monica
Gregory,Julianna
Cognetta Jr.,Armand B.
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Pathergy
Cutaneous squamous cell carcinoma
Fluorouracil
Retinoid
datacite.titles.title.fl_str_mv Cutaneous pathergy and squamous cell carcinoma: a report of two cases
dc.creator.none.fl_str_mv Miller,Austinn C.
Bhate,Chinmoy
Constantinescu,Monica
Gregory,Julianna
Cognetta Jr.,Armand B.
dc.format.none.fl_str_mv text/html
dc.identifier.none.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S2795-50012025000300203
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Permanyer Publications
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.source.none.fl_str_mv Portuguese Journal of Dermatology and Venereology v.83 n.3 2025
dc.subject.none.fl_str_mv Pathergy
Cutaneous squamous cell carcinoma
Fluorouracil
Retinoid
dc.title.fl_str_mv Cutaneous pathergy and squamous cell carcinoma: a report of two cases
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_93fc
description Abstract Cutaneous pathergy is a phenomenon demonstrating an exaggerated wound response following minor trauma. While often associated with inflammatory conditions, its association with carcinogenesis is less often described. Recognition of this important phenomenon may be challenging to clinicians who do not encounter it regularly. Cutaneous pathergic squamous cell carcinomas (SCCs) most typically occur as numerous eruptive neoplasms in female patients in sites of trauma or in the background of lichen simplex chronicus or lichenoid dermatoses. Management can be difficult and is typically non-surgical. Herein, we describe two cases of pathergic SCCs and our approach to treatment.
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eu_rights_str_mv openAccess
format report
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identifier.url.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S2795-50012025000300203
instacron_str SciELO
institution Fundação para a Ciência e Tecnologia
instname_str Fundação para a Ciência e Tecnologia
language eng
network_acronym_str scielopt
network_name_str SciELO Portugal
oai_identifier_str oai:scielo:S2795-50012025000300203
organization_str_mv urn:organizationAcronym:scielo
person_str_mv Miller,Austinn C.
Bhate,Chinmoy
Constantinescu,Monica
Gregory,Julianna
Cognetta Jr.,Armand B.
publishDate 2025
publisher.none.fl_str_mv Permanyer Publications
reponame_str SciELO Portugal
repository_id_str urn:repositoryAcronym:scielopt
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spelling Cutaneous pathergy and squamous cell carcinoma: a report of two casesMiller,Austinn C.Bhate,ChinmoyConstantinescu,MonicaGregory,JuliannaCognetta Jr.,Armand B.PathergyCutaneous squamous cell carcinomaFluorouracilRetinoidopen accesshttp://purl.org/coar/access_right/c_abf2http://scielo.pt/scielo.php?script=sci_arttext&pid=S2795-50012025000300203URLhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S2795-50012025000300203URLHasVersion2025-09-01Abstract Cutaneous pathergy is a phenomenon demonstrating an exaggerated wound response following minor trauma. While often associated with inflammatory conditions, its association with carcinogenesis is less often described. Recognition of this important phenomenon may be challenging to clinicians who do not encounter it regularly. Cutaneous pathergic squamous cell carcinomas (SCCs) most typically occur as numerous eruptive neoplasms in female patients in sites of trauma or in the background of lichen simplex chronicus or lichenoid dermatoses. Management can be difficult and is typically non-surgical. Herein, we describe two cases of pathergic SCCs and our approach to treatment.Permanyer PublicationsPortuguese Journal of Dermatology and Venereology v.83 n.3 2025text/htmlengreporthttp://purl.org/coar/resource_type/c_93fcother research product
spellingShingle Cutaneous pathergy and squamous cell carcinoma: a report of two cases
Miller,Austinn C.
Pathergy
Cutaneous squamous cell carcinoma
Fluorouracil
Retinoid
status SINGLETON
subject.fl_str_mv Pathergy
Cutaneous squamous cell carcinoma
Fluorouracil
Retinoid
title Cutaneous pathergy and squamous cell carcinoma: a report of two cases
title_full Cutaneous pathergy and squamous cell carcinoma: a report of two cases
title_fullStr Cutaneous pathergy and squamous cell carcinoma: a report of two cases
title_full_unstemmed Cutaneous pathergy and squamous cell carcinoma: a report of two cases
title_short Cutaneous pathergy and squamous cell carcinoma: a report of two cases
title_sort Cutaneous pathergy and squamous cell carcinoma: a report of two cases
topic Pathergy
Cutaneous squamous cell carcinoma
Fluorouracil
Retinoid
topic_facet Pathergy
Cutaneous squamous cell carcinoma
Fluorouracil
Retinoid
url http://scielo.pt/scielo.php?script=sci_arttext&pid=S2795-50012025000300203
visible 1