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COVID-19-induced rhabdomyolysis in an adolescent: A rare presentation

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Resumo:Abstract Viral infections are a well-known cause of myositis. The clinical presentation may vary from mild myalgia to severe muscle injury. Coronavirus disease 2019 (COVID-19), a viral respiratory disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), can be a cause of myositis and of rhabdomyolysis, a rare and severe complication. A previously healthy 11-year-old female adolescent with COVID-19 presented to the Emergency Department with lower limb pain and inability to walk. The initial laboratory study revealed a marked elevation of muscular enzymes, particularly creatine kinase (13046 UI/L; reference value 149 UI/L). Urine dipstick test reacted positively for hemoglobinuria. The patient started treatment with aggressive intravenous hydration, with progressive clinical and analytical improvement. Musculoskeletal symptoms associated with COVID-19 are a frequent complaint, with potentially severe complications, such as rhabdomyolysis. A proper and timely diagnosis can prevent further clinical deterioration and enable adequate treatment and follow-up.
Autores principais:Calejo,Rita
Outros Autores:Queirós,Joana; Brandão,Carla; Barroso,Fábio; Machado,Leonilde
Assunto:COVID-19 muscle myositis rhabdomyolysis
Ano:2022
País:Portugal
Tipo de documento:relatório
Tipo de acesso:acesso aberto
Instituição associada:Fundação para a Ciência e Tecnologia
Idioma:inglês
Origem:SciELO Portugal
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author Calejo,Rita
author2 Queirós,Joana
Brandão,Carla
Barroso,Fábio
Machado,Leonilde
author2_role author
author
author
author
author_facet Calejo,Rita
Queirós,Joana
Brandão,Carla
Barroso,Fábio
Machado,Leonilde
author_role author
country_str PT
creators_json_txt [{\"Person.name\":\"Calejo,Rita\"},{\"Person.name\":\"Queirós,Joana\"},{\"Person.name\":\"Brandão,Carla\"},{\"Person.name\":\"Barroso,Fábio\"},{\"Person.name\":\"Machado,Leonilde\"}]
datacite.creators.creator.creatorName.fl_str_mv Calejo,Rita
Queirós,Joana
Brandão,Carla
Barroso,Fábio
Machado,Leonilde
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv COVID-19
muscle
myositis
rhabdomyolysis
datacite.titles.title.fl_str_mv COVID-19-induced rhabdomyolysis in an adolescent: A rare presentation
dc.creator.none.fl_str_mv Calejo,Rita
Queirós,Joana
Brandão,Carla
Barroso,Fábio
Machado,Leonilde
dc.format.none.fl_str_mv text/html
dc.identifier.none.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-07542022000300317
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Centro Hospitalar do Porto
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.source.none.fl_str_mv Nascer e Crescer v.31 n.3 2022
dc.subject.none.fl_str_mv COVID-19
muscle
myositis
rhabdomyolysis
dc.title.fl_str_mv COVID-19-induced rhabdomyolysis in an adolescent: A rare presentation
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_93fc
description Abstract Viral infections are a well-known cause of myositis. The clinical presentation may vary from mild myalgia to severe muscle injury. Coronavirus disease 2019 (COVID-19), a viral respiratory disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), can be a cause of myositis and of rhabdomyolysis, a rare and severe complication. A previously healthy 11-year-old female adolescent with COVID-19 presented to the Emergency Department with lower limb pain and inability to walk. The initial laboratory study revealed a marked elevation of muscular enzymes, particularly creatine kinase (13046 UI/L; reference value 149 UI/L). Urine dipstick test reacted positively for hemoglobinuria. The patient started treatment with aggressive intravenous hydration, with progressive clinical and analytical improvement. Musculoskeletal symptoms associated with COVID-19 are a frequent complaint, with potentially severe complications, such as rhabdomyolysis. A proper and timely diagnosis can prevent further clinical deterioration and enable adequate treatment and follow-up.
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language eng
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network_name_str SciELO Portugal
oai_identifier_str oai:scielo:S0872-07542022000300317
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person_str_mv Calejo,Rita
Queirós,Joana
Brandão,Carla
Barroso,Fábio
Machado,Leonilde
publishDate 2022
publisher.none.fl_str_mv Centro Hospitalar do Porto
reponame_str SciELO Portugal
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spelling COVID-19-induced rhabdomyolysis in an adolescent: A rare presentationCalejo,RitaQueirós,JoanaBrandão,CarlaBarroso,FábioMachado,LeonildeCOVID-19musclemyositisrhabdomyolysisopen accesshttp://purl.org/coar/access_right/c_abf2http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-07542022000300317URLhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-07542022000300317URLHasVersion2022-09-01Abstract Viral infections are a well-known cause of myositis. The clinical presentation may vary from mild myalgia to severe muscle injury. Coronavirus disease 2019 (COVID-19), a viral respiratory disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), can be a cause of myositis and of rhabdomyolysis, a rare and severe complication. A previously healthy 11-year-old female adolescent with COVID-19 presented to the Emergency Department with lower limb pain and inability to walk. The initial laboratory study revealed a marked elevation of muscular enzymes, particularly creatine kinase (13046 UI/L; reference value 149 UI/L). Urine dipstick test reacted positively for hemoglobinuria. The patient started treatment with aggressive intravenous hydration, with progressive clinical and analytical improvement. Musculoskeletal symptoms associated with COVID-19 are a frequent complaint, with potentially severe complications, such as rhabdomyolysis. A proper and timely diagnosis can prevent further clinical deterioration and enable adequate treatment and follow-up.Centro Hospitalar do PortoNascer e Crescer v.31 n.3 2022text/htmlengreporthttp://purl.org/coar/resource_type/c_93fcother research product
spellingShingle COVID-19-induced rhabdomyolysis in an adolescent: A rare presentation
Calejo,Rita
COVID-19
muscle
myositis
rhabdomyolysis
status SINGLETON
subject.fl_str_mv COVID-19
muscle
myositis
rhabdomyolysis
title COVID-19-induced rhabdomyolysis in an adolescent: A rare presentation
title_full COVID-19-induced rhabdomyolysis in an adolescent: A rare presentation
title_fullStr COVID-19-induced rhabdomyolysis in an adolescent: A rare presentation
title_full_unstemmed COVID-19-induced rhabdomyolysis in an adolescent: A rare presentation
title_short COVID-19-induced rhabdomyolysis in an adolescent: A rare presentation
title_sort COVID-19-induced rhabdomyolysis in an adolescent: A rare presentation
topic COVID-19
muscle
myositis
rhabdomyolysis
topic_facet COVID-19
muscle
myositis
rhabdomyolysis
url http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-07542022000300317
visible 1