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Prosthetic vascular graft infections: a center experience

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Resumo:Introduction: Prosthetic graft infection is a major complication of vascular surgery associated with high morbid-mortality rates. This retrospective non-randomized single center study evaluated our experience in the management of prosthetic vascular graft infections. Methods: We review the clinical files of patients who had vascular grafts implanted at our center between June 2007 and December 2011 and analysed the cases that developed Samson group 3, 4 and 5 infections until December 2012. Results: From June 2007 to December 2012, 18 consecutive patients (14 males, 4 females) with median age 70 years were admitted to our institution with the diagnosis of vascular graft infection accounting for an incidence of 3.8%. 50% of these infections were early infections and MRSA was the most prevalent pathogen. 44% of infections were due to infection of a femoro-popliteal bypass. Using Samson classification, 72% were group 4 and 5 infections. We performed graft preservation in one patient, graft excision without revascularization in 50% (nine) patients; Excision + insitu replacement in 39% (seven) patients; Excision + Extra-anatomic bypass in one patient. Our amputation rate was 55% and our related death rate was 16%. Conclusions: Our amputation and mortality rates are according the published reviews. Besides allowing recognition of our reality this offers the opportunity to review diagnosis and therapeutic issues in prosthetic vascular graft infections. Each situation needs to be individualized as there is no consensus nor guiding algorithms about what should be the best medical treatment
Autores principais:Sousa,Juliana Varino
Outros Autores:Antunes,Luís; Mendes,Carolina; Marinho,André; Gonçalves,Anabela; Gonçalves,Óscar; Matos,Albuquerque
Assunto:Prosthetic vascular graft Infection Antibiotic treatment Surgical treatment
Ano:2014
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Fundação para a Ciência e Tecnologia
Idioma:inglês
Origem:SciELO Portugal
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author Sousa,Juliana Varino
author2 Antunes,Luís
Mendes,Carolina
Marinho,André
Gonçalves,Anabela
Gonçalves,Óscar
Matos,Albuquerque
author2_role author
author
author
author
author
author
author_facet Sousa,Juliana Varino
Antunes,Luís
Mendes,Carolina
Marinho,André
Gonçalves,Anabela
Gonçalves,Óscar
Matos,Albuquerque
author_role author
country_str PT
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datacite.creators.creator.creatorName.fl_str_mv Sousa,Juliana Varino
Antunes,Luís
Mendes,Carolina
Marinho,André
Gonçalves,Anabela
Gonçalves,Óscar
Matos,Albuquerque
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Prosthetic vascular graft
Infection
Antibiotic treatment
Surgical treatment
datacite.titles.title.fl_str_mv Prosthetic vascular graft infections: a center experience
dc.creator.none.fl_str_mv Sousa,Juliana Varino
Antunes,Luís
Mendes,Carolina
Marinho,André
Gonçalves,Anabela
Gonçalves,Óscar
Matos,Albuquerque
dc.format.none.fl_str_mv text/html
dc.identifier.none.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-706X2014000200005
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Angiologia e Cirurgia Vascular
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.source.none.fl_str_mv Angiologia e Cirurgia Vascular v.10 n.2 2014
dc.subject.none.fl_str_mv Prosthetic vascular graft
Infection
Antibiotic treatment
Surgical treatment
dc.title.fl_str_mv Prosthetic vascular graft infections: a center experience
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description Introduction: Prosthetic graft infection is a major complication of vascular surgery associated with high morbid-mortality rates. This retrospective non-randomized single center study evaluated our experience in the management of prosthetic vascular graft infections. Methods: We review the clinical files of patients who had vascular grafts implanted at our center between June 2007 and December 2011 and analysed the cases that developed Samson group 3, 4 and 5 infections until December 2012. Results: From June 2007 to December 2012, 18 consecutive patients (14 males, 4 females) with median age 70 years were admitted to our institution with the diagnosis of vascular graft infection accounting for an incidence of 3.8%. 50% of these infections were early infections and MRSA was the most prevalent pathogen. 44% of infections were due to infection of a femoro-popliteal bypass. Using Samson classification, 72% were group 4 and 5 infections. We performed graft preservation in one patient, graft excision without revascularization in 50% (nine) patients; Excision + insitu replacement in 39% (seven) patients; Excision + Extra-anatomic bypass in one patient. Our amputation rate was 55% and our related death rate was 16%. Conclusions: Our amputation and mortality rates are according the published reviews. Besides allowing recognition of our reality this offers the opportunity to review diagnosis and therapeutic issues in prosthetic vascular graft infections. Each situation needs to be individualized as there is no consensus nor guiding algorithms about what should be the best medical treatment
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person_str_mv Sousa,Juliana Varino
Antunes,Luís
Mendes,Carolina
Marinho,André
Gonçalves,Anabela
Gonçalves,Óscar
Matos,Albuquerque
publishDate 2014
publisher.none.fl_str_mv Sociedade Portuguesa de Angiologia e Cirurgia Vascular
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spelling Prosthetic vascular graft infections: a center experienceSousa,Juliana VarinoAntunes,LuísMendes,CarolinaMarinho,AndréGonçalves,AnabelaGonçalves,ÓscarMatos,AlbuquerqueProsthetic vascular graftInfectionAntibiotic treatmentSurgical treatmentopen accesshttp://purl.org/coar/access_right/c_abf2http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-706X2014000200005URLhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-706X2014000200005URLHasVersion2014-06-01Introduction: Prosthetic graft infection is a major complication of vascular surgery associated with high morbid-mortality rates. This retrospective non-randomized single center study evaluated our experience in the management of prosthetic vascular graft infections. Methods: We review the clinical files of patients who had vascular grafts implanted at our center between June 2007 and December 2011 and analysed the cases that developed Samson group 3, 4 and 5 infections until December 2012. Results: From June 2007 to December 2012, 18 consecutive patients (14 males, 4 females) with median age 70 years were admitted to our institution with the diagnosis of vascular graft infection accounting for an incidence of 3.8%. 50% of these infections were early infections and MRSA was the most prevalent pathogen. 44% of infections were due to infection of a femoro-popliteal bypass. Using Samson classification, 72% were group 4 and 5 infections. We performed graft preservation in one patient, graft excision without revascularization in 50% (nine) patients; Excision + insitu replacement in 39% (seven) patients; Excision + Extra-anatomic bypass in one patient. Our amputation rate was 55% and our related death rate was 16%. Conclusions: Our amputation and mortality rates are according the published reviews. Besides allowing recognition of our reality this offers the opportunity to review diagnosis and therapeutic issues in prosthetic vascular graft infections. Each situation needs to be individualized as there is no consensus nor guiding algorithms about what should be the best medical treatmentSociedade Portuguesa de Angiologia e Cirurgia VascularAngiologia e Cirurgia Vascular v.10 n.2 2014text/htmlengjournal articlehttp://purl.org/coar/resource_type/c_6501literature
spellingShingle Prosthetic vascular graft infections: a center experience
Sousa,Juliana Varino
Prosthetic vascular graft
Infection
Antibiotic treatment
Surgical treatment
status SINGLETON
subject.fl_str_mv Prosthetic vascular graft
Infection
Antibiotic treatment
Surgical treatment
title Prosthetic vascular graft infections: a center experience
title_full Prosthetic vascular graft infections: a center experience
title_fullStr Prosthetic vascular graft infections: a center experience
title_full_unstemmed Prosthetic vascular graft infections: a center experience
title_short Prosthetic vascular graft infections: a center experience
title_sort Prosthetic vascular graft infections: a center experience
topic Prosthetic vascular graft
Infection
Antibiotic treatment
Surgical treatment
topic_facet Prosthetic vascular graft
Infection
Antibiotic treatment
Surgical treatment
url http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-706X2014000200005
visible 1