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Neutropenic enterocolitis (typhlitis) in a kidney transplant patient: A case report

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Summary:Typhlitis is a clinical entity rare in adults, reported in immunosuppressed patients. It is a life-threatening condition that occurs in neutropenic patients due to compromised integrity of the bowel wall and its exact pathogenesis is not completely understood. We report a 35-year-old man with a post deceased donor renal and pancreas transplantation status who presented fever and febrile neutropenia. Three days after admission he presented hematochezia with a hemoglobin drop. Colonoscopy revealed "ileum mucosa with multiforme ulcers" and since no other etiology was found, typhlitis was considered. He gradually improved with support treatment and was able to be managed non-operatively. To our knowledge, there are only six other reports of typhlitis in kidney transplant recipients.
Main Authors:Alves,Rita Valério
Other Authors:Falcão,Luís; Soares,Elsa; Mendes,Milena; Cotovio,Patrícia; Caeiro,Fernando; Aires,Inês; Silva,Cecília; Remédio,Francisco; Ferreira,Aníbal; Nolasco,Fernando
Subject:Neutropenic enterocolitis typhlitis kidney transplant
Year:2020
Country:Portugal
Document type:report
Access type:open access
Associated institution:Fundação para a Ciência e Tecnologia
Language:English
Origin:SciELO Portugal

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