Publicação
Case of Flexural Exanthema as a Presenting Sign for COVID-19
| Resumo: | ABSTRACT We report a case of a 84-year-old male hospitalized for bacterial pneumonia who, during hospitalization, developed a flexural exanthema in parallel with a positive swab for SARS-CoV-2. Supportive therapy was instituted, the rash disappeared in 7 days and the patient fully recovered. At the same time, two other cases of SARS-CoV-2 infection occurred in the same ward. Histopathology and immunohistochemistry of a skin biopsy showed a scarce predominantly perivascular lymphocytic infiltration in the upper dermis, predominantly by CD4+ T cells, a slight epidermotropism, spongiosis and focal parakeratosis, compatible with a viral exanthema or a maculopapular drug eruption. Patch testing with possible culprit drugs were negative. We seek to add value in understanding all the manifestations of SARS-CoV-2 infection and to draw attention to the importance of early identification of skin manifestations in association with COVID-19. |
|---|---|
| Autores principais: | Oliveira,Raquel |
| Outros Autores: | Gonçalo,Margarida; Faria,Carlos; Donaire,David; Barbosa,Benilde; Cardoso,José Carlos; Julião,Maria José; Moura,José; Carvalho,Armando |
| Assunto: | Coronavirus Infections COVID-19 Exanthema SARS-CoV-2. |
| Ano: | 2020 |
| País: | Portugal |
| Tipo de documento: | relatório |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Fundação para a Ciência e Tecnologia |
| Idioma: | inglês |
| Origem: | SciELO Portugal |
| _version_ | 1868441917459529728 |
|---|---|
| author | Oliveira,Raquel |
| author2 | Gonçalo,Margarida Faria,Carlos Donaire,David Barbosa,Benilde Cardoso,José Carlos Julião,Maria José Moura,José Carvalho,Armando |
| author2_role | author author author author author author author author |
| author_facet | Oliveira,Raquel Gonçalo,Margarida Faria,Carlos Donaire,David Barbosa,Benilde Cardoso,José Carlos Julião,Maria José Moura,José Carvalho,Armando |
| author_role | author |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Oliveira,Raquel\"},{\"Person.name\":\"Gonçalo,Margarida\"},{\"Person.name\":\"Faria,Carlos\"},{\"Person.name\":\"Donaire,David\"},{\"Person.name\":\"Barbosa,Benilde\"},{\"Person.name\":\"Cardoso,José Carlos\"},{\"Person.name\":\"Julião,Maria José\"},{\"Person.name\":\"Moura,José\"},{\"Person.name\":\"Carvalho,Armando\"}] |
| datacite.creators.creator.creatorName.fl_str_mv | Oliveira,Raquel Gonçalo,Margarida Faria,Carlos Donaire,David Barbosa,Benilde Cardoso,José Carlos Julião,Maria José Moura,José Carvalho,Armando |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Coronavirus Infections COVID-19 Exanthema SARS-CoV-2. |
| datacite.titles.title.fl_str_mv | Case of Flexural Exanthema as a Presenting Sign for COVID-19 |
| dc.creator.none.fl_str_mv | Oliveira,Raquel Gonçalo,Margarida Faria,Carlos Donaire,David Barbosa,Benilde Cardoso,José Carlos Julião,Maria José Moura,José Carvalho,Armando |
| dc.format.none.fl_str_mv | text/html |
| dc.identifier.none.fl_str_mv | http://scielo.pt/scielo.php?script=sci_arttext&pid=S2182-23952020000300069 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Sociedade Portuguesa de Dermatologia e Venereologia |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.source.none.fl_str_mv | Revista da Sociedade Portuguesa de Dermatologia e Venereologia v.78 n.3 2020 |
| dc.subject.none.fl_str_mv | Coronavirus Infections COVID-19 Exanthema SARS-CoV-2. |
| dc.title.fl_str_mv | Case of Flexural Exanthema as a Presenting Sign for COVID-19 |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_93fc |
| description | ABSTRACT We report a case of a 84-year-old male hospitalized for bacterial pneumonia who, during hospitalization, developed a flexural exanthema in parallel with a positive swab for SARS-CoV-2. Supportive therapy was instituted, the rash disappeared in 7 days and the patient fully recovered. At the same time, two other cases of SARS-CoV-2 infection occurred in the same ward. Histopathology and immunohistochemistry of a skin biopsy showed a scarce predominantly perivascular lymphocytic infiltration in the upper dermis, predominantly by CD4+ T cells, a slight epidermotropism, spongiosis and focal parakeratosis, compatible with a viral exanthema or a maculopapular drug eruption. Patch testing with possible culprit drugs were negative. We seek to add value in understanding all the manifestations of SARS-CoV-2 infection and to draw attention to the importance of early identification of skin manifestations in association with COVID-19. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | report |
| id | scielopt_e2f8df9df4ce7f4f9eb27725ea820cd7 |
| identifier.url.fl_str_mv | http://scielo.pt/scielo.php?script=sci_arttext&pid=S2182-23952020000300069 |
| instacron_str | SciELO |
| institution | Fundação para a Ciência e Tecnologia |
| instname_str | Fundação para a Ciência e Tecnologia |
| language | eng |
| network_acronym_str | scielopt |
| network_name_str | SciELO Portugal |
| oai_identifier_str | oai:scielo:S2182-23952020000300069 |
| organization_str_mv | urn:organizationAcronym:scielo |
| person_str_mv | Oliveira,Raquel Gonçalo,Margarida Faria,Carlos Donaire,David Barbosa,Benilde Cardoso,José Carlos Julião,Maria José Moura,José Carvalho,Armando |
| publishDate | 2020 |
| publisher.none.fl_str_mv | Sociedade Portuguesa de Dermatologia e Venereologia |
| reponame_str | SciELO Portugal |
| repository_id_str | urn:repositoryAcronym:scielopt |
| service_str_mv | urn:repositoryAcronym:scielopt |
| spelling | Case of Flexural Exanthema as a Presenting Sign for COVID-19Oliveira,RaquelGonçalo,MargaridaFaria,CarlosDonaire,DavidBarbosa,BenildeCardoso,José CarlosJulião,Maria JoséMoura,JoséCarvalho,ArmandoCoronavirus InfectionsCOVID-19ExanthemaSARS-CoV-2.open accesshttp://purl.org/coar/access_right/c_abf2http://scielo.pt/scielo.php?script=sci_arttext&pid=S2182-23952020000300069URLhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S2182-23952020000300069URLHasVersion2020-09-01ABSTRACT We report a case of a 84-year-old male hospitalized for bacterial pneumonia who, during hospitalization, developed a flexural exanthema in parallel with a positive swab for SARS-CoV-2. Supportive therapy was instituted, the rash disappeared in 7 days and the patient fully recovered. At the same time, two other cases of SARS-CoV-2 infection occurred in the same ward. Histopathology and immunohistochemistry of a skin biopsy showed a scarce predominantly perivascular lymphocytic infiltration in the upper dermis, predominantly by CD4+ T cells, a slight epidermotropism, spongiosis and focal parakeratosis, compatible with a viral exanthema or a maculopapular drug eruption. Patch testing with possible culprit drugs were negative. We seek to add value in understanding all the manifestations of SARS-CoV-2 infection and to draw attention to the importance of early identification of skin manifestations in association with COVID-19.Sociedade Portuguesa de Dermatologia e VenereologiaRevista da Sociedade Portuguesa de Dermatologia e Venereologia v.78 n.3 2020text/htmlengreporthttp://purl.org/coar/resource_type/c_93fcother research product |
| spellingShingle | Case of Flexural Exanthema as a Presenting Sign for COVID-19 Oliveira,Raquel Coronavirus Infections COVID-19 Exanthema SARS-CoV-2. |
| status | SINGLETON |
| subject.fl_str_mv | Coronavirus Infections COVID-19 Exanthema SARS-CoV-2. |
| title | Case of Flexural Exanthema as a Presenting Sign for COVID-19 |
| title_full | Case of Flexural Exanthema as a Presenting Sign for COVID-19 |
| title_fullStr | Case of Flexural Exanthema as a Presenting Sign for COVID-19 |
| title_full_unstemmed | Case of Flexural Exanthema as a Presenting Sign for COVID-19 |
| title_short | Case of Flexural Exanthema as a Presenting Sign for COVID-19 |
| title_sort | Case of Flexural Exanthema as a Presenting Sign for COVID-19 |
| topic | Coronavirus Infections COVID-19 Exanthema SARS-CoV-2. |
| topic_facet | Coronavirus Infections COVID-19 Exanthema SARS-CoV-2. |
| url | http://scielo.pt/scielo.php?script=sci_arttext&pid=S2182-23952020000300069 |
| visible | 1 |