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IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME: A POTENTIAL PITFALL IN THE MANAGEMENT OF KAPOSI’S SARCOMA IN HIV POSITIVE PATIENTS? – A CASE REPORT

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Detalhes bibliográficos
Resumo:The variety of immune reconstitution inflammatory syndrome’s (IRIS) clinical presentations makes this syndrome a challenge, in that it is difficult to manage opportunistic infections and other serious clinical conditions related to the manifestation of this syndrome. The relevance of immune reconstitution inflammatory syndrome – associated with Kaposi sarcoma (IRIS-KS) after initiation of highly active antiretroviral therapy (HAART) is noteworthy, mainly in coun tries that still have high levels of transmission of sexually transmitted diseases and HIV. Clinicians and dermatologists should be aware to identify signs and symptoms of this neoplasm progression and to differentiate them from KS related IRIS according to the recent classification criteria of this disease and antiretroviral therapy should not be discontinued in the most cases.
Autores principais:Ladeira de Oliveira, Felipe
Outros Autores:Sírio, Deborah Maria Brito; Cerutti, Gisele; de Natividade, Natalia Barreiros; de Menezes, Vinicius Martins; Miranda, Alice; Azulay-Abulafia, Luna; Nery, José Augusto da Costa
Assunto:Antiretroviral therapy highly active HIV infections Sarcoma Kaposi Infecção por VIH Sarcoma de Kaposi HAART
Ano:2014
País:Portugal
Tipo de documento:artigo
Instituição associada:Sociedade Portuguesa de Dermatologia e Venereologia
Idioma:português
Origem:Portuguese Journal of Dermatology
Descrição
Resumo:The variety of immune reconstitution inflammatory syndrome’s (IRIS) clinical presentations makes this syndrome a challenge, in that it is difficult to manage opportunistic infections and other serious clinical conditions related to the manifestation of this syndrome. The relevance of immune reconstitution inflammatory syndrome – associated with Kaposi sarcoma (IRIS-KS) after initiation of highly active antiretroviral therapy (HAART) is noteworthy, mainly in coun tries that still have high levels of transmission of sexually transmitted diseases and HIV. Clinicians and dermatologists should be aware to identify signs and symptoms of this neoplasm progression and to differentiate them from KS related IRIS according to the recent classification criteria of this disease and antiretroviral therapy should not be discontinued in the most cases.