Publicação

Hemophagocytic Syndrome: A Suspect to Have in Mind

Ver documento

Detalhes bibliográficos
Resumo:The hemophagocytic syndrome is a rare and potentially fatalcondition, characterized by uncontrolled immune systemactivation, with symptoms and signs of extreme systemic inflammation.As the manifestations are mostly unspecific, itsdiagnosis requires a high degree of suspicion, in order toimplement adequate and timely therapy. The authors presentthe case of a 19 year-old boy, previously healthy, with a suspectedlung infection due to a period of three weeks fever.He presented a sudden increase of liver enzymes and slightpancytopenia, skin rash and hepatosplenomegaly. The elevatedvalues of ferritin and interleukin-2 soluble receptor, aswell as the presence of hemophagocytosis in bone marrow,confirmed the diagnosis of hemophagocytic syndrome. Afterfour weeks of dexamethasone, total resolution of symptomsand laboratorial normalization were achieved.
Autores principais:Souto Moura, Teresa
Outros Autores:Simões, Inês; Lemos, Marcos; Azevedo, Luísa; Gerivaz, Rita; Fonseca, Paula
Assunto:Corticosteroides Ferritinas/sangue Linfohistiocitose Hemofagocítica/diagnóstico Linfohistiocitose Hemofagocítica/ tratamento Adrenal Cortex Hormones Ferritins/blood Lymphohistiocytosis, Hemophagocytic/diagnosis Lymphohistiocytosis, Hemophagocytic/therapy
Ano:2017
País:Portugal
Tipo de documento:artigo
Tipo de acesso:unknown
Instituição associada:Sociedade Portuguesa de Medicina Interna
Idioma:português
Origem:Revista Portuguesa de Medicina Interna

Registos relacionados

Registos relacionados