Publicação
Depression, reduced physical activity and the risk of heart disease: a prospective cohort of European middle-aged and older adults
| Resumo: | Objective: To assess the impact of depression and physical activity (PA) of different intensities on the incidence of heart disease. Methods: A prospective cohort study with 20 645 European middle-aged and older adults (mean baseline age 63 years; 55.1% women; median follow-up 9.5 years) was conducted using data from the Survey of Health, Ageing and Retirement in Europe. The EURO-D 12-item scale assessed depression. Moderate-intensity and vigorous-intensity PA and heart disease diagnoses were self-reported. We classified participants into the following four groups: (1) depression plus low PA, (2) no depression plus low PA, (3) depression plus moderate/high PA, (4) no depression plus moderate/high PA. Hazard ratio (HR) and 95% confidence interval (CI) were estimated using Cox proportional hazards models adjusted for confounders. Results: Compared with having depression and low PA levels, adjusted HR for heart disease similarly decreased for participants with depression and moderate/high PA (moderate-intensity PA: HR=0.63, 95% CI=0.50, 0.78; vigorous-intensity PA: HR=0.69, 95% CI=0.53, 0.89) and participants without depression and low PA (moderate-intensity PA: HR=0.64, 95% CI=0.50, 0.82; vigorous-intensity PA: HR=0.68, 95% CI=0.58, 0.80). The greatest risk reduction was found in participants without depression and moderate/high PA (moderate-intensity PA: HR=0.46, 95% CI=0.37, 0.55; vigorous-intensity PA: HR=0.48, 95% CI=0.40, 0.58). Conclusion: Moderate-intensity and vigorous-intensity PA seems to counteract the increased risk for heart disease associated with depression. This highlights the importance of PA as a possible intervention strategy aiming to manage the risk of heart disease among people with depression. |
|---|---|
| Autores principais: | Peralta, Miguel |
| Outros Autores: | Nascimento, Marcelo; Ferrari, Gerson; Gouveia, Elvio; Marques, Adilson |
| Assunto: | Cardiovascular Diseases Depression Epidemiology Exercise Physical activity |
| Ano: | 2025 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso restrito |
| Instituição associada: | Universidade de Lisboa |
| Idioma: | inglês |
| Origem: | Repositório da Universidade de Lisboa |
| _version_ | 1865920781215596544 |
|---|---|
| author | Peralta, Miguel |
| author2 | Nascimento, Marcelo Ferrari, Gerson Gouveia, Elvio Marques, Adilson |
| author2_role | author author author author |
| author_facet | Peralta, Miguel Peralta, Miguel Nascimento, Marcelo Ferrari, Gerson Gouveia, Elvio Marques, Adilson Nascimento, Marcelo Ferrari, Gerson Gouveia, Elvio Marques, Adilson |
| author_role | author |
| contributor_name_str_mv | Repositório Científico de Acesso Aberto da ULisboa |
| country_str | PT |
| creators_json_str | [{\"Person.name\":\"Peralta, Miguel\",\"Person.identifier.orcid\":\"0000-0001-6072-6012\"},{\"Person.name\":\"Nascimento, Marcelo\"},{\"Person.name\":\"Ferrari, Gerson\"},{\"Person.name\":\"Gouveia, Elvio\",\"Person.identifier.orcid\":\"0000-0003-0927-692X\"},{\"Person.name\":\"Marques, Adilson\",\"Person.identifier.orcid\":\"0000-0001-9850-7771\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Repositório Científico de Acesso Aberto da ULisboa |
| datacite.creators.creator.creatorName.fl_str_mv | Peralta, Miguel Nascimento, Marcelo Ferrari, Gerson Gouveia, Elvio Marques, Adilson |
| datacite.date.Accepted.fl_str_mv | 2025-01-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2025-06-04T13:58:10Z |
| datacite.date.embargoed.fl_str_mv | 2025-06-04T13:58:10Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_16ec |
| datacite.subjects.subject.fl_str_mv | Cardiovascular Diseases Depression Epidemiology Exercise Physical activity |
| datacite.titles.title.fl_str_mv | Depression, reduced physical activity and the risk of heart disease: a prospective cohort of European middle-aged and older adults |
| dc.contributor.none.fl_str_mv | Repositório Científico de Acesso Aberto da ULisboa |
| dc.creator.none.fl_str_mv | Peralta, Miguel Nascimento, Marcelo Ferrari, Gerson Gouveia, Elvio Marques, Adilson |
| dc.date.Accepted.fl_str_mv | 2025-01-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2025-06-04T13:58:10Z |
| dc.date.embargoed.fl_str_mv | 2025-06-04T13:58:10Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | http://hdl.handle.net/10400.5/101286 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | BMJ Publishing Group Ltd. |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_16ec |
| dc.subject.none.fl_str_mv | Cardiovascular Diseases Depression Epidemiology Exercise Physical activity |
| dc.title.fl_str_mv | Depression, reduced physical activity and the risk of heart disease: a prospective cohort of European middle-aged and older adults |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Objective: To assess the impact of depression and physical activity (PA) of different intensities on the incidence of heart disease. Methods: A prospective cohort study with 20 645 European middle-aged and older adults (mean baseline age 63 years; 55.1% women; median follow-up 9.5 years) was conducted using data from the Survey of Health, Ageing and Retirement in Europe. The EURO-D 12-item scale assessed depression. Moderate-intensity and vigorous-intensity PA and heart disease diagnoses were self-reported. We classified participants into the following four groups: (1) depression plus low PA, (2) no depression plus low PA, (3) depression plus moderate/high PA, (4) no depression plus moderate/high PA. Hazard ratio (HR) and 95% confidence interval (CI) were estimated using Cox proportional hazards models adjusted for confounders. Results: Compared with having depression and low PA levels, adjusted HR for heart disease similarly decreased for participants with depression and moderate/high PA (moderate-intensity PA: HR=0.63, 95% CI=0.50, 0.78; vigorous-intensity PA: HR=0.69, 95% CI=0.53, 0.89) and participants without depression and low PA (moderate-intensity PA: HR=0.64, 95% CI=0.50, 0.82; vigorous-intensity PA: HR=0.68, 95% CI=0.58, 0.80). The greatest risk reduction was found in participants without depression and moderate/high PA (moderate-intensity PA: HR=0.46, 95% CI=0.37, 0.55; vigorous-intensity PA: HR=0.48, 95% CI=0.40, 0.58). Conclusion: Moderate-intensity and vigorous-intensity PA seems to counteract the increased risk for heart disease associated with depression. This highlights the importance of PA as a possible intervention strategy aiming to manage the risk of heart disease among people with depression. |
| dirty | 0 |
| eu_rights_str_mv | restrictedAccess |
| format | article |
| fulltext.url.fl_str_mv | https://repositorio.ulisboa.pt/bitstreams/99198a91-aa35-4bb6-a48b-1055764e3282/download |
| id | ul_2be2d25a1fb7c0a080e1625ecdba7fad |
| identifier.url.fl_str_mv | http://hdl.handle.net/10400.5/101286 |
| instacron_str | ul |
| institution | Universidade de Lisboa |
| instname_str | Universidade de Lisboa |
| language | eng |
| network_acronym_str | ul |
| network_name_str | Repositório da Universidade de Lisboa |
| oai_identifier_str | oai:repositorio.ulisboa.pt:10400.5/101286 |
| organization_str_mv | urn:organizationAcronym:ul |
| person_str_mv | Peralta, Miguel Peralta, Miguel https://www.ciencia-id.pt/C31A-3D60-1F01 C31A-3D60-1F01 http://orcid.org/0000-0001-6072-6012 0000-0001-6072-6012 Nascimento, Marcelo Ferrari, Gerson Gouveia, Elvio Gouveia, Elvio https://www.ciencia-id.pt/3B10-8BDF-0D67 3B10-8BDF-0D67 http://orcid.org/0000-0003-0927-692X 0000-0003-0927-692X Marques, Adilson Marques, Adilson https://www.ciencia-id.pt/5F18-F9C3-11CB 5F18-F9C3-11CB http://orcid.org/0000-0001-9850-7771 0000-0001-9850-7771 |
| publishDate | 2025 |
| publisher.none.fl_str_mv | BMJ Publishing Group Ltd. |
| reponame_str | Repositório da Universidade de Lisboa |
| repository_id_str | urn:repositoryAcronym:ul |
| service_str_mv | urn:repositoryAcronym:ul |
| spelling | engBMJ Publishing Group Ltd.pt_PTObjective: To assess the impact of depression and physical activity (PA) of different intensities on the incidence of heart disease. Methods: A prospective cohort study with 20 645 European middle-aged and older adults (mean baseline age 63 years; 55.1% women; median follow-up 9.5 years) was conducted using data from the Survey of Health, Ageing and Retirement in Europe. The EURO-D 12-item scale assessed depression. Moderate-intensity and vigorous-intensity PA and heart disease diagnoses were self-reported. We classified participants into the following four groups: (1) depression plus low PA, (2) no depression plus low PA, (3) depression plus moderate/high PA, (4) no depression plus moderate/high PA. Hazard ratio (HR) and 95% confidence interval (CI) were estimated using Cox proportional hazards models adjusted for confounders. Results: Compared with having depression and low PA levels, adjusted HR for heart disease similarly decreased for participants with depression and moderate/high PA (moderate-intensity PA: HR=0.63, 95% CI=0.50, 0.78; vigorous-intensity PA: HR=0.69, 95% CI=0.53, 0.89) and participants without depression and low PA (moderate-intensity PA: HR=0.64, 95% CI=0.50, 0.82; vigorous-intensity PA: HR=0.68, 95% CI=0.58, 0.80). The greatest risk reduction was found in participants without depression and moderate/high PA (moderate-intensity PA: HR=0.46, 95% CI=0.37, 0.55; vigorous-intensity PA: HR=0.48, 95% CI=0.40, 0.58). Conclusion: Moderate-intensity and vigorous-intensity PA seems to counteract the increased risk for heart disease associated with depression. This highlights the importance of PA as a possible intervention strategy aiming to manage the risk of heart disease among people with depression.application/pdfpt_PTDepression, reduced physical activity and the risk of heart disease: a prospective cohort of European middle-aged and older adultsPersonalPeralta, MiguelDSpacehttp://dspace.org/items/4242c0b6-5a64-4b90-a14d-0209dfca31d0DSpacehttp://dspace.org/items/4242c0b6-5a64-4b90-a14d-0209dfca31d0PeraltaMiguelCiência IDhttps://www.ciencia-id.ptC31A-3D60-1F01ORCIDhttp://orcid.org0000-0001-6072-6012Researcher IDhttps://www.researcherid.comH-1666-2017Researcher IDhttps://www.researcherid.comH-1666-2017Scopus Author IDhttps://www.scopus.com56306465800Nascimento, MarceloFerrari, GersonPersonalGouveia, ElvioDSpacehttp://dspace.org/items/54a5bf32-51cd-4e5a-b56a-d242a214a958DSpacehttp://dspace.org/items/54a5bf32-51cd-4e5a-b56a-d242a214a958GouveiaElvioCiência IDhttps://www.ciencia-id.pt3B10-8BDF-0D67ORCIDhttp://orcid.org0000-0003-0927-692XResearcher IDhttps://www.researcherid.comF-9156-2015Scopus Author IDhttps://www.scopus.com36637395800PersonalMarques, AdilsonDSpacehttp://dspace.org/items/1971699a-ff03-48f6-92b9-6a3d7bce1111DSpacehttp://dspace.org/items/1971699a-ff03-48f6-92b9-6a3d7bce1111MarquesAdilsonCiência IDhttps://www.ciencia-id.pt5F18-F9C3-11CBORCIDhttp://orcid.org0000-0001-9850-7771Researcher IDhttps://www.researcherid.comK-4529-2014Researcher IDhttps://www.researcherid.comK-4529-2014Scopus Author IDhttps://www.scopus.com55082567000HostingInstitutionOrganizationalRepositório Científico de Acesso Aberto da ULisboae-mailmailto:repositorio@reitoria.ulisboa.ptrepositorio@reitoria.ulisboa.ptISSNIsPartOf0306-3674DOIIsPartOf10.1136/bjsports-2024-1087802025-06-04T13:58:10Z20252025-01-01T00:00:00ZHandlehttp://hdl.handle.net/10400.5/101286http://purl.org/coar/access_right/c_16ecrestricted accessCardiovascular DiseasesDepressionEpidemiologyExercisePhysical activity902464 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_16ecapplication/pdffulltexthttps://repositorio.ulisboa.pt/bitstreams/99198a91-aa35-4bb6-a48b-1055764e3282/downloadBritish Journal of Sports Medicine |
| spellingShingle | Depression, reduced physical activity and the risk of heart disease: a prospective cohort of European middle-aged and older adults Depression, reduced physical activity and the risk of heart disease: a prospective cohort of European middle-aged and older adults Peralta, Miguel Cardiovascular Diseases Depression Epidemiology Exercise Physical activity Peralta, Miguel Cardiovascular Diseases Depression Epidemiology Exercise Physical activity |
| status | SINGLETON |
| subject.fl_str_mv | Cardiovascular Diseases Depression Epidemiology Exercise Physical activity |
| title | Depression, reduced physical activity and the risk of heart disease: a prospective cohort of European middle-aged and older adults |
| title_full | Depression, reduced physical activity and the risk of heart disease: a prospective cohort of European middle-aged and older adults |
| title_fullStr | Depression, reduced physical activity and the risk of heart disease: a prospective cohort of European middle-aged and older adults Depression, reduced physical activity and the risk of heart disease: a prospective cohort of European middle-aged and older adults |
| title_full_unstemmed | Depression, reduced physical activity and the risk of heart disease: a prospective cohort of European middle-aged and older adults Depression, reduced physical activity and the risk of heart disease: a prospective cohort of European middle-aged and older adults |
| title_short | Depression, reduced physical activity and the risk of heart disease: a prospective cohort of European middle-aged and older adults |
| title_sort | Depression, reduced physical activity and the risk of heart disease: a prospective cohort of European middle-aged and older adults |
| topic | Cardiovascular Diseases Depression Epidemiology Exercise Physical activity |
| topic_facet | Cardiovascular Diseases Depression Epidemiology Exercise Physical activity |
| url | http://hdl.handle.net/10400.5/101286 |
| visible | 1 |