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Distribution of Cryptosporidium subtypes in humans and domestic and wild ruminants in Portugal

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Resumo:To investigate the transmission of cryptosporidiosis in Portugal, Cryptosporidium hominis and Cryptosporidium parvum from HIV-infected patients, cattle, and wild ruminants were characterized by sequence analysis of the 60-kDa glycoprotein (GP60) gene. Fourteen subtypes within nine subtype families were identified, and three of the subtype families (If, IIb, and IId) were restricted or largely limited to Portugal. Parasites from cattle from various regions in Portugal and wild ruminants in Lisbon showed limited genetic heterogeneity (only two subtype families). All wild ruminants had the same subtype, which was also the predominant subtype in cattle all over Portugal and was found in nine HIV-infected patients in Lisbon. Two other C. parvum subtypes were only restricted to limited locations. In contrast, human parasites displayed 13 subtypes in nine subtype families, with most of the infections caused by parasites in Ib, IIa, IIc, and IId families. Two of the C. parvum subtype families (IIc and IIb) had only been found in humans. The high overall parasite diversity and high percentage of C. hominis infections attributable to Ib and C. parvum infections to IId represent unique characteristics of Cryptosporidium transmission in humans in Portugal.
Autores principais:Alves, Margarida
Outros Autores:Xiao, Lihua; Antunes, Francisco; Matos, Olga
Assunto:Cryptosporidiosis Cryptosporidium parvum Zoonotic transmission Wild ruminant Kuwait City
Ano:2006
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso restrito
Instituição associada:Universidade de Lisboa
Idioma:inglês
Origem:Repositório da Universidade de Lisboa
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author Alves, Margarida
author2 Xiao, Lihua
Antunes, Francisco
Matos, Olga
author2_role author
author
author
author_facet Alves, Margarida
Xiao, Lihua
Antunes, Francisco
Matos, Olga
author_role author
contributor_name_str_mv Repositório Científico de Acesso Aberto da ULisboa
country_str PT
creators_json_txt [{\"Person.name\":\"Alves, Margarida\"},{\"Person.name\":\"Xiao, Lihua\"},{\"Person.name\":\"Antunes, Francisco\",\"Person.identifier.orcid\":\"0000-0001-7932-1154\"},{\"Person.name\":\"Matos, Olga\",\"Person.identifier.orcid\":\"0000-0001-5793-7716\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Repositório Científico de Acesso Aberto da ULisboa
datacite.creators.creator.creatorName.fl_str_mv Alves, Margarida
Xiao, Lihua
Antunes, Francisco
Matos, Olga
datacite.date.Accepted.fl_str_mv 2006-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2025-07-31T10:59:50Z
datacite.date.embargoed.fl_str_mv 2025-07-31T10:59:50Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_16ec
datacite.subjects.subject.fl_str_mv Cryptosporidiosis
Cryptosporidium parvum
Zoonotic transmission
Wild ruminant
Kuwait City
datacite.titles.title.fl_str_mv Distribution of Cryptosporidium subtypes in humans and domestic and wild ruminants in Portugal
dc.contributor.none.fl_str_mv Repositório Científico de Acesso Aberto da ULisboa
dc.creator.none.fl_str_mv Alves, Margarida
Xiao, Lihua
Antunes, Francisco
Matos, Olga
dc.date.Accepted.fl_str_mv 2006-01-01T00:00:00Z
dc.date.available.fl_str_mv 2025-07-31T10:59:50Z
dc.date.embargoed.fl_str_mv 2025-07-31T10:59:50Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10400.5/102581
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Springer Nature
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_16ec
dc.subject.none.fl_str_mv Cryptosporidiosis
Cryptosporidium parvum
Zoonotic transmission
Wild ruminant
Kuwait City
dc.title.fl_str_mv Distribution of Cryptosporidium subtypes in humans and domestic and wild ruminants in Portugal
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description To investigate the transmission of cryptosporidiosis in Portugal, Cryptosporidium hominis and Cryptosporidium parvum from HIV-infected patients, cattle, and wild ruminants were characterized by sequence analysis of the 60-kDa glycoprotein (GP60) gene. Fourteen subtypes within nine subtype families were identified, and three of the subtype families (If, IIb, and IId) were restricted or largely limited to Portugal. Parasites from cattle from various regions in Portugal and wild ruminants in Lisbon showed limited genetic heterogeneity (only two subtype families). All wild ruminants had the same subtype, which was also the predominant subtype in cattle all over Portugal and was found in nine HIV-infected patients in Lisbon. Two other C. parvum subtypes were only restricted to limited locations. In contrast, human parasites displayed 13 subtypes in nine subtype families, with most of the infections caused by parasites in Ib, IIa, IIc, and IId families. Two of the C. parvum subtype families (IIc and IIb) had only been found in humans. The high overall parasite diversity and high percentage of C. hominis infections attributable to Ib and C. parvum infections to IId represent unique characteristics of Cryptosporidium transmission in humans in Portugal.
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eu_rights_str_mv restrictedAccess
format article
fulltext.url.fl_str_mv https://repositorio.ulisboa.pt/bitstreams/7fc6da62-f321-4bc3-8c73-076f05851006/download
funding.funder.alternateName_str_mv FCT
funding.funder.identifier_str_mv http://doi.org/10.13039/501100001871
funding.funder.name_str_mv Fundação para a Ciência e a Tecnologia
funding.name_str_mv POCI
id ul_4ffcaa3bf0a71e2a4262cef24c2ea61e
identifier.url.fl_str_mv http://hdl.handle.net/10400.5/102581
instacron_str ul
institution Universidade de Lisboa
instname_str Universidade de Lisboa
language eng
network_acronym_str ul
network_name_str Repositório da Universidade de Lisboa
oai_identifier_str oai:repositorio.ulisboa.pt:10400.5/102581
organization_str_mv urn:organizationAcronym:ul
person_str_mv Alves, Margarida
Xiao, Lihua
Antunes, Francisco
Antunes, Francisco
http://orcid.org/0000-0001-7932-1154
0000-0001-7932-1154
Matos, Olga
Matos, Olga
https://www.ciencia-id.pt/751F-FE84-CCF2
751F-FE84-CCF2
http://orcid.org/0000-0001-5793-7716
0000-0001-5793-7716
publishDate 2006
publisher.none.fl_str_mv Springer Nature
reponame_str Repositório da Universidade de Lisboa
repository_id_str urn:repositoryAcronym:ul
service_str_mv urn:repositoryAcronym:ul
spelling engSpringer Naturept_PTTo investigate the transmission of cryptosporidiosis in Portugal, Cryptosporidium hominis and Cryptosporidium parvum from HIV-infected patients, cattle, and wild ruminants were characterized by sequence analysis of the 60-kDa glycoprotein (GP60) gene. Fourteen subtypes within nine subtype families were identified, and three of the subtype families (If, IIb, and IId) were restricted or largely limited to Portugal. Parasites from cattle from various regions in Portugal and wild ruminants in Lisbon showed limited genetic heterogeneity (only two subtype families). All wild ruminants had the same subtype, which was also the predominant subtype in cattle all over Portugal and was found in nine HIV-infected patients in Lisbon. Two other C. parvum subtypes were only restricted to limited locations. In contrast, human parasites displayed 13 subtypes in nine subtype families, with most of the infections caused by parasites in Ib, IIa, IIc, and IId families. Two of the C. parvum subtype families (IIc and IIb) had only been found in humans. The high overall parasite diversity and high percentage of C. hominis infections attributable to Ib and C. parvum infections to IId represent unique characteristics of Cryptosporidium transmission in humans in Portugal.application/pdfpt_PTDistribution of Cryptosporidium subtypes in humans and domestic and wild ruminants in PortugalAlves, MargaridaXiao, LihuaPersonalAntunes, FranciscoDSpacehttp://dspace.org/items/a28493a5-9101-4173-8863-74ee946d6cedDSpacehttp://dspace.org/items/a28493a5-9101-4173-8863-74ee946d6cedAntunesFranciscoORCIDhttp://orcid.org0000-0001-7932-1154Scopus Author IDhttps://www.scopus.com7006648941PersonalMatos, OlgaDSpacehttp://dspace.org/items/be64fd9b-8fc7-450b-b84d-c667e7d78760DSpacehttp://dspace.org/items/be64fd9b-8fc7-450b-b84d-c667e7d78760Guerreiro de MatosOlga MariaCiência IDhttps://www.ciencia-id.pt751F-FE84-CCF2ORCIDhttp://orcid.org0000-0001-5793-7716HostingInstitutionOrganizationalRepositório Científico de Acesso Aberto da ULisboae-mailmailto:repositorio@reitoria.ulisboa.ptrepositorio@reitoria.ulisboa.ptISSNIsPartOf0932-0113DOIIsPartOf10.1007/s00436-006-0164-52025-07-31T10:59:50Z20062006-01-01T00:00:00ZHandlehttp://hdl.handle.net/10400.5/102581http://purl.org/coar/access_right/c_16ecrestricted accessCryptosporidiosisCryptosporidium parvumZoonotic transmissionWild ruminantKuwait City127477 bytesFundação para a Ciência e a TecnologiaStudy of the Transmission Dynamics of Cryptosporidium Using Molecular Analysis of isolates from Humans, Animals and WaterPOCICrossref Funder IDhttp://doi.org/10.13039/501100001871literaturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_16ecapplication/pdffulltexthttps://repositorio.ulisboa.pt/bitstreams/7fc6da62-f321-4bc3-8c73-076f05851006/downloadParasitology Research993287292
spellingShingle Distribution of Cryptosporidium subtypes in humans and domestic and wild ruminants in Portugal
Alves, Margarida
Cryptosporidiosis
Cryptosporidium parvum
Zoonotic transmission
Wild ruminant
Kuwait City
status SINGLETON
subject.fl_str_mv Cryptosporidiosis
Cryptosporidium parvum
Zoonotic transmission
Wild ruminant
Kuwait City
title Distribution of Cryptosporidium subtypes in humans and domestic and wild ruminants in Portugal
title_full Distribution of Cryptosporidium subtypes in humans and domestic and wild ruminants in Portugal
title_fullStr Distribution of Cryptosporidium subtypes in humans and domestic and wild ruminants in Portugal
title_full_unstemmed Distribution of Cryptosporidium subtypes in humans and domestic and wild ruminants in Portugal
title_short Distribution of Cryptosporidium subtypes in humans and domestic and wild ruminants in Portugal
title_sort Distribution of Cryptosporidium subtypes in humans and domestic and wild ruminants in Portugal
topic Cryptosporidiosis
Cryptosporidium parvum
Zoonotic transmission
Wild ruminant
Kuwait City
topic_facet Cryptosporidiosis
Cryptosporidium parvum
Zoonotic transmission
Wild ruminant
Kuwait City
url http://hdl.handle.net/10400.5/102581
visible 1