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Disturbances in kalemia and their relationship with azotemia and mortality in ill pet rabbits

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Resumo:ABSTRACT - Prevalence of kalemia distubances and its impact on survivability in pet rabbits has not been previously studied, while in human medicine and dog and cat medicine, both hyperkalemia and hypokalemia have been associated with higher mortality rates. This retrospective clinical study intended to describe the prevalence of kalemia disturbances and their association with azotemia and mortality, to better understand their impact in ill pet rabbit patients (n=634). Hyperkalemia was greatly related with azotemia in ill pet rabbits (Mann-Whitney U; P < 0,001) with rabbits that presented hyperkalemic having a 7,9 times higher chances (P < 0,001) of being azotemic. All animals that presented hyperkalemia and had creatinine measured were hypercreatimic. Hypokalemia was recorded in 111 rabbits (17,5%) and hyperkalemia in 44 rabbits (6,94%). Rabbits that died showed significantly higher blood potassium levels (Mann-Whitney U; P < 0,001). When comparing normokalemic individuals to the ones that presented hyperkalemic, hyperkalemia posed a threat to ill rabbits’ survival, since they showed significant differences in their survivability (P < 0,001) with a 4,3 times greater risk of death in the first day. The same was observed in the first week survivability (P < 0,001) with rabbits that presented hyperkalemia at hospitalization having 3,2 times greater mortality. There was also an increase in relative risk of death and mortality when the degree of hyperkalemia rose in these rabbits. When compared, rabbits’ mortality in those that presented hypokalemia and those that were normokalemic there were no significant statistical differences (P = 0,79) meaning that hypokalemic animals do not have a greater risk of death. This study concludes that blood potassium evaluation is important in ill pet rabbits, that hyperkalemia in rabbits in greatly associated with renal impairment and that hyperkalemia meant a greater risk of death for the patient while being hypokalemic did not
Autores principais:Pinto, Daniel Marques
Assunto:Rabbit (Oryctolagus cuniculus) Potassium Kalemia Azotemia Mortality Coelho (Oryctolagus cuniculus) Potássio Caliémia Azotémia Mortalidade
Ano:2024
País:Portugal
Tipo de documento:dissertação de mestrado
Tipo de acesso:acesso aberto
Instituição associada:Universidade de Lisboa
Idioma:inglês
Origem:Repositório da Universidade de Lisboa

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