Publicação
Infective endocarditis as the cause of death: a population-based study in Portugal, from 2002 to 2018
| Resumo: | Introduction: Infective endocarditis presents a high rate of morbidity and mortality. Population-based studies addressing mortality caused by infective endocarditis in Portugal are scarce. We aimed to study deaths caused by Infective endocarditis, as well as corresponding demographics and temporal trends. Material and methods: Retrospective cohort study of all patients whose main cause of death was Infective endocarditis in Portugal from 2002 to 2018. The data was obtained from the national death certificate information system. Results: In Portugal, 3634 people died from infective endocarditis throughout the 17-year study period - infective endocarditis specific mortality rate of 2.1 per 100 000 habitants. Of all deceased, 89% were at least 60 years old, and most were women (55%). Overall, 72% died in a healthcare institution. An annual 9% increase in the incidence death rate from Infective endocarditis was observed, with a significant upward trend during the colder months. Discussion: In Portugal, mortality by infective endocarditis increased, mainly affecting older patients and women, and which can partially be explained by factors such as ageing of the population. The management of older patients with infective endocarditis is challenging as they present a higher number of comorbidities, more valvular heart disease and valve implants, invasive medical procedures and are less likely to undergo cardiac surgery. Conclusion: In addition to data on the evolution of demographics in Portugal, it is crucial to study the incidence of infective endocarditis over time to help explain these findings. The identification of factors that can be used to better model national health policies to improve clinical outcomes of infective endocarditis in Portugal is also required. |
|---|---|
| Autores principais: | Santos de Sousa, Catarina Isabel |
| Outros Autores: | Ribeiro, Ruy; Pinto, Fausto J. |
| Assunto: | Endocarditis/epidemiology Endocarditis/mortality Portugal Seasons |
| Ano: | 2021 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade de Lisboa |
| Idioma: | inglês |
| Origem: | Repositório da Universidade de Lisboa |
| _version_ | 1866811122301009920 |
|---|---|
| author | Santos de Sousa, Catarina Isabel |
| author2 | Ribeiro, Ruy Pinto, Fausto J. |
| author2_role | author author |
| author_facet | Santos de Sousa, Catarina Isabel Ribeiro, Ruy Pinto, Fausto J. |
| author_role | author |
| contributor_name_str_mv | Repositório Científico de Acesso Aberto da ULisboa |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Santos de Sousa, Catarina Isabel\",\"Person.identifier.orcid\":\"0000-0003-1709-6283\"},{\"Person.name\":\"Ribeiro, Ruy\",\"Person.identifier.orcid\":\"0000-0002-3988-8241\"},{\"Person.name\":\"Pinto, Fausto J.\",\"Person.identifier.orcid\":\"0000-0002-8034-4529\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Repositório Científico de Acesso Aberto da ULisboa |
| datacite.creators.creator.creatorName.fl_str_mv | Santos de Sousa, Catarina Isabel Ribeiro, Ruy Pinto, Fausto J. |
| datacite.date.Accepted.fl_str_mv | 2021-01-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2021-12-03T16:11:54Z |
| datacite.date.embargoed.fl_str_mv | 2021-12-03T16:11:54Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Endocarditis/epidemiology Endocarditis/mortality Portugal Seasons |
| datacite.titles.title.fl_str_mv | Infective endocarditis as the cause of death: a population-based study in Portugal, from 2002 to 2018 Endocardite infecciosa como causa de morte: um estudo populacional em Portugal, de 2002 a 2018 |
| dc.contributor.none.fl_str_mv | Repositório Científico de Acesso Aberto da ULisboa |
| dc.creator.none.fl_str_mv | Santos de Sousa, Catarina Isabel Ribeiro, Ruy Pinto, Fausto J. |
| dc.date.Accepted.fl_str_mv | 2021-01-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2021-12-03T16:11:54Z |
| dc.date.embargoed.fl_str_mv | 2021-12-03T16:11:54Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | http://hdl.handle.net/10451/50273 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Ordem dos Médicos |
| dc.rights.cclincense.fl_str_mv | http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | Endocarditis/epidemiology Endocarditis/mortality Portugal Seasons |
| dc.title.fl_str_mv | Infective endocarditis as the cause of death: a population-based study in Portugal, from 2002 to 2018 Endocardite infecciosa como causa de morte: um estudo populacional em Portugal, de 2002 a 2018 |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Introduction: Infective endocarditis presents a high rate of morbidity and mortality. Population-based studies addressing mortality caused by infective endocarditis in Portugal are scarce. We aimed to study deaths caused by Infective endocarditis, as well as corresponding demographics and temporal trends. Material and methods: Retrospective cohort study of all patients whose main cause of death was Infective endocarditis in Portugal from 2002 to 2018. The data was obtained from the national death certificate information system. Results: In Portugal, 3634 people died from infective endocarditis throughout the 17-year study period - infective endocarditis specific mortality rate of 2.1 per 100 000 habitants. Of all deceased, 89% were at least 60 years old, and most were women (55%). Overall, 72% died in a healthcare institution. An annual 9% increase in the incidence death rate from Infective endocarditis was observed, with a significant upward trend during the colder months. Discussion: In Portugal, mortality by infective endocarditis increased, mainly affecting older patients and women, and which can partially be explained by factors such as ageing of the population. The management of older patients with infective endocarditis is challenging as they present a higher number of comorbidities, more valvular heart disease and valve implants, invasive medical procedures and are less likely to undergo cardiac surgery. Conclusion: In addition to data on the evolution of demographics in Portugal, it is crucial to study the incidence of infective endocarditis over time to help explain these findings. The identification of factors that can be used to better model national health policies to improve clinical outcomes of infective endocarditis in Portugal is also required. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| fulltext.url.fl_str_mv | https://repositorio.ulisboa.pt/bitstreams/41292ab5-17c3-4ce7-bdaf-06103e11b367/download |
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| identifier.url.fl_str_mv | http://hdl.handle.net/10451/50273 |
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| institution | Universidade de Lisboa |
| instname_str | Universidade de Lisboa |
| language | eng |
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| network_name_str | Repositório da Universidade de Lisboa |
| oai_identifier_str | oai:repositorio.ulisboa.pt:10451/50273 |
| organization_str_mv | urn:organizationAcronym:ul |
| person_str_mv | Santos de Sousa, Catarina Isabel Santos de Sousa, Catarina Isabel https://www.ciencia-id.pt/9E18-4F83-D92D 9E18-4F83-D92D http://orcid.org/0000-0003-1709-6283 0000-0003-1709-6283 Ribeiro, Ruy Ribeiro, Ruy https://www.ciencia-id.pt/9A15-E40B-738F 9A15-E40B-738F http://orcid.org/0000-0002-3988-8241 0000-0002-3988-8241 Pinto, Fausto J. Pinto, Fausto J. https://www.ciencia-id.pt/C311-AEDD-6DBB C311-AEDD-6DBB http://orcid.org/0000-0002-8034-4529 0000-0002-8034-4529 |
| publishDate | 2021 |
| publisher.none.fl_str_mv | Ordem dos Médicos |
| reponame_str | Repositório da Universidade de Lisboa |
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| spelling | engOrdem dos Médicospt_PTIntroduction: Infective endocarditis presents a high rate of morbidity and mortality. Population-based studies addressing mortality caused by infective endocarditis in Portugal are scarce. We aimed to study deaths caused by Infective endocarditis, as well as corresponding demographics and temporal trends. Material and methods: Retrospective cohort study of all patients whose main cause of death was Infective endocarditis in Portugal from 2002 to 2018. The data was obtained from the national death certificate information system. Results: In Portugal, 3634 people died from infective endocarditis throughout the 17-year study period - infective endocarditis specific mortality rate of 2.1 per 100 000 habitants. Of all deceased, 89% were at least 60 years old, and most were women (55%). Overall, 72% died in a healthcare institution. An annual 9% increase in the incidence death rate from Infective endocarditis was observed, with a significant upward trend during the colder months. Discussion: In Portugal, mortality by infective endocarditis increased, mainly affecting older patients and women, and which can partially be explained by factors such as ageing of the population. The management of older patients with infective endocarditis is challenging as they present a higher number of comorbidities, more valvular heart disease and valve implants, invasive medical procedures and are less likely to undergo cardiac surgery. Conclusion: In addition to data on the evolution of demographics in Portugal, it is crucial to study the incidence of infective endocarditis over time to help explain these findings. The identification of factors that can be used to better model national health policies to improve clinical outcomes of infective endocarditis in Portugal is also required.application/pdfpt_PTInfective endocarditis as the cause of death: a population-based study in Portugal, from 2002 to 2018AlternativeTitlept_PTEndocardite infecciosa como causa de morte: um estudo populacional em Portugal, de 2002 a 2018PersonalSantos de Sousa, Catarina IsabelDSpacehttp://dspace.org/items/1058897e-37d9-4305-9ede-50ddba6128ccDSpacehttp://dspace.org/items/1058897e-37d9-4305-9ede-50ddba6128ccSantos de SousaCatarina IsabelCiência IDhttps://www.ciencia-id.pt9E18-4F83-D92DORCIDhttp://orcid.org0000-0003-1709-6283PersonalRibeiro, RuyDSpacehttp://dspace.org/items/215b5cf4-faab-41ea-becf-c63bed56d3d1DSpacehttp://dspace.org/items/215b5cf4-faab-41ea-becf-c63bed56d3d1RibeiroRuy MiguelCiência IDhttps://www.ciencia-id.pt9A15-E40B-738FORCIDhttp://orcid.org0000-0002-3988-8241PersonalPinto, Fausto J.DSpacehttp://dspace.org/items/5f44176f-69f5-482c-83cd-ab94425a6ec3DSpacehttp://dspace.org/items/5f44176f-69f5-482c-83cd-ab94425a6ec3PintoFausto J.Ciência IDhttps://www.ciencia-id.ptC311-AEDD-6DBBORCIDhttp://orcid.org0000-0002-8034-4529Researcher IDhttps://www.researcherid.comG-9363-2015Researcher IDhttps://www.researcherid.comGQA-4584-2022Scopus Author IDhttps://www.scopus.com7102740158HostingInstitutionOrganizationalRepositório Científico de Acesso Aberto da ULisboae-mailmailto:repositorio@reitoria.ulisboa.ptrepositorio@reitoria.ulisboa.ptISSNIsPartOf0870-399XDOIIsPartOf10.20344/amp.146092021-12-03T16:11:54Z20212021-01-01T00:00:00ZHandlehttp://hdl.handle.net/10451/50273http://purl.org/coar/access_right/c_abf2open accessEndocarditis/epidemiologyEndocarditis/mortalityPortugalSeasons837390 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal article2021http://creativecommons.org/licenses/by-nc-nd/4.0/http://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://repositorio.ulisboa.pt/bitstreams/41292ab5-17c3-4ce7-bdaf-06103e11b367/downloadActa Médica Portuguesa3413 |
| spellingShingle | Infective endocarditis as the cause of death: a population-based study in Portugal, from 2002 to 2018 Santos de Sousa, Catarina Isabel Endocarditis/epidemiology Endocarditis/mortality Portugal Seasons |
| status | SINGLETON |
| subject.fl_str_mv | Endocarditis/epidemiology Endocarditis/mortality Portugal Seasons |
| title | Infective endocarditis as the cause of death: a population-based study in Portugal, from 2002 to 2018 |
| title_full | Infective endocarditis as the cause of death: a population-based study in Portugal, from 2002 to 2018 |
| title_fullStr | Infective endocarditis as the cause of death: a population-based study in Portugal, from 2002 to 2018 |
| title_full_unstemmed | Infective endocarditis as the cause of death: a population-based study in Portugal, from 2002 to 2018 |
| title_short | Infective endocarditis as the cause of death: a population-based study in Portugal, from 2002 to 2018 |
| title_sort | Infective endocarditis as the cause of death: a population-based study in Portugal, from 2002 to 2018 |
| topic | Endocarditis/epidemiology Endocarditis/mortality Portugal Seasons |
| topic_facet | Endocarditis/epidemiology Endocarditis/mortality Portugal Seasons |
| url | http://hdl.handle.net/10451/50273 |
| visible | 1 |