Publicação
A Dangerous Couple: Sequential Effect of Phosphorus Flame-Retardant and Polyurethane Decrease Locomotor Activity in Planarian Girardia tigrina
| Resumo: | Understanding the interplay among organophosphorus flame retardants (OPFRs), microplastics, and freshwater organisms is crucial for unravelling the dynamics within freshwater environments and foreseeing the potential impacts of organic pollutants and plastic contamination. For that purpose, the present research assessed the exposure impact of 10 mg L−1 flame-retardant aluminium diethylphosphinate (ALPI), 10 μg mg−1liver microplastics polyurethane (PU), and the combination of ALPI and PU on the freshwater planarian Girardia tigrina. The exposure to both ALPI and PU revealed a sequential effect, i.e., a decrease in locomotor activity, while oxidative stress biomarkers (total glutathione, catalase, glutathione S-transferase, lipid peroxidation) and metabolic responses (cholinesterase activity, electron transport system, and lactate dehydrogenase) remained unaffected. Despite this fact, it was possible to observe that the range of physiological responses in exposed organisms varied, in particular in the cases of the electron transport system, cholinesterase activity, glutathione S-transferase, catalase, and levels of total glutathione and proteins, showing that the energetic costs for detoxification and antioxidant capacity might be causing a lesser amount of energy allocated for the planarian activity. By examining the physiological, behavioural, and ecological responses of planarians to these pollutants, insights can be gained into broader ecosystem-level effects and inform strategies for mitigating environmental risks associated with OPFRs and microplastic pollution in freshwater environments. |
|---|---|
| Autores principais: | Bjedov, Dora |
| Outros Autores: | Barbosa, Rone S.; Oliveira, Danielle Palma de; Dorta, Daniel Junqueira; Sarmento, Maíra Ignacio; Sarmento, Renato Almeida; Silva, Ana L. Patrício; Gravato, C |
| Ano: | 2024 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade de Lisboa |
| Idioma: | inglês |
| Origem: | Repositório da Universidade de Lisboa |
| _version_ | 1866809479091191808 |
|---|---|
| author | Bjedov, Dora |
| author2 | Barbosa, Rone S. Oliveira, Danielle Palma de Dorta, Daniel Junqueira Sarmento, Maíra Ignacio Sarmento, Renato Almeida Silva, Ana L. Patrício Gravato, C |
| author2_role | author author author author author author author |
| author_facet | Bjedov, Dora Barbosa, Rone S. Oliveira, Danielle Palma de Dorta, Daniel Junqueira Sarmento, Maíra Ignacio Sarmento, Renato Almeida Silva, Ana L. Patrício Gravato, C |
| author_role | author |
| contributor_name_str_mv | Repositório Científico de Acesso Aberto da ULisboa |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Bjedov, Dora\",\"Person.identifier.orcid\":\"0000-0003-1059-7907\"},{\"Person.name\":\"Barbosa, Rone S.\"},{\"Person.name\":\"Oliveira, Danielle Palma de\"},{\"Person.name\":\"Dorta, Daniel Junqueira\"},{\"Person.name\":\"Sarmento, Maíra Ignacio\"},{\"Person.name\":\"Sarmento, Renato Almeida\"},{\"Person.name\":\"Silva, Ana L. Patrício\"},{\"Person.name\":\"Gravato, C\",\"Person.identifier.orcid\":\"0000-0003-0562-6945\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Repositório Científico de Acesso Aberto da ULisboa |
| datacite.creators.creator.creatorName.fl_str_mv | Bjedov, Dora Barbosa, Rone S. Oliveira, Danielle Palma de Dorta, Daniel Junqueira Sarmento, Maíra Ignacio Sarmento, Renato Almeida Silva, Ana L. Patrício Gravato, C |
| datacite.date.Accepted.fl_str_mv | 2024-05-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2024-12-19T11:48:07Z |
| datacite.date.embargoed.fl_str_mv | 2024-12-19T11:48:07Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.titles.title.fl_str_mv | A Dangerous Couple: Sequential Effect of Phosphorus Flame-Retardant and Polyurethane Decrease Locomotor Activity in Planarian Girardia tigrina |
| dc.contributor.none.fl_str_mv | Repositório Científico de Acesso Aberto da ULisboa |
| dc.creator.none.fl_str_mv | Bjedov, Dora Barbosa, Rone S. Oliveira, Danielle Palma de Dorta, Daniel Junqueira Sarmento, Maíra Ignacio Sarmento, Renato Almeida Silva, Ana L. Patrício Gravato, C |
| dc.date.Accepted.fl_str_mv | 2024-05-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2024-12-19T11:48:07Z |
| dc.date.embargoed.fl_str_mv | 2024-12-19T11:48:07Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | http://hdl.handle.net/10400.5/96494 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | MDPI |
| dc.rights.cclincense.fl_str_mv | http://creativecommons.org/licenses/by/4.0/ |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.title.fl_str_mv | A Dangerous Couple: Sequential Effect of Phosphorus Flame-Retardant and Polyurethane Decrease Locomotor Activity in Planarian Girardia tigrina |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Understanding the interplay among organophosphorus flame retardants (OPFRs), microplastics, and freshwater organisms is crucial for unravelling the dynamics within freshwater environments and foreseeing the potential impacts of organic pollutants and plastic contamination. For that purpose, the present research assessed the exposure impact of 10 mg L−1 flame-retardant aluminium diethylphosphinate (ALPI), 10 μg mg−1liver microplastics polyurethane (PU), and the combination of ALPI and PU on the freshwater planarian Girardia tigrina. The exposure to both ALPI and PU revealed a sequential effect, i.e., a decrease in locomotor activity, while oxidative stress biomarkers (total glutathione, catalase, glutathione S-transferase, lipid peroxidation) and metabolic responses (cholinesterase activity, electron transport system, and lactate dehydrogenase) remained unaffected. Despite this fact, it was possible to observe that the range of physiological responses in exposed organisms varied, in particular in the cases of the electron transport system, cholinesterase activity, glutathione S-transferase, catalase, and levels of total glutathione and proteins, showing that the energetic costs for detoxification and antioxidant capacity might be causing a lesser amount of energy allocated for the planarian activity. By examining the physiological, behavioural, and ecological responses of planarians to these pollutants, insights can be gained into broader ecosystem-level effects and inform strategies for mitigating environmental risks associated with OPFRs and microplastic pollution in freshwater environments. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| fulltext.url.fl_str_mv | https://repositorio.ulisboa.pt/bitstreams/d4c6ae6d-63db-46f1-ba1a-e9e1dfd1ec88/download |
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| identifier.url.fl_str_mv | http://hdl.handle.net/10400.5/96494 |
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| institution | Universidade de Lisboa |
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| language | eng |
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| person_str_mv | Bjedov, Dora Bjedov, Dora http://orcid.org/0000-0003-1059-7907 0000-0003-1059-7907 Barbosa, Rone S. Oliveira, Danielle Palma de Dorta, Daniel Junqueira Sarmento, Maíra Ignacio Sarmento, Renato Almeida Silva, Ana L. Patrício Gravato, C Gravato, C https://www.ciencia-id.pt/1414-2BF3-C834 1414-2BF3-C834 http://orcid.org/0000-0003-0562-6945 0000-0003-0562-6945 |
| publishDate | 2024 |
| publisher.none.fl_str_mv | MDPI |
| reponame_str | Repositório da Universidade de Lisboa |
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| spelling | engMDPIpt_PTUnderstanding the interplay among organophosphorus flame retardants (OPFRs), microplastics, and freshwater organisms is crucial for unravelling the dynamics within freshwater environments and foreseeing the potential impacts of organic pollutants and plastic contamination. For that purpose, the present research assessed the exposure impact of 10 mg L−1 flame-retardant aluminium diethylphosphinate (ALPI), 10 μg mg−1liver microplastics polyurethane (PU), and the combination of ALPI and PU on the freshwater planarian Girardia tigrina. The exposure to both ALPI and PU revealed a sequential effect, i.e., a decrease in locomotor activity, while oxidative stress biomarkers (total glutathione, catalase, glutathione S-transferase, lipid peroxidation) and metabolic responses (cholinesterase activity, electron transport system, and lactate dehydrogenase) remained unaffected. Despite this fact, it was possible to observe that the range of physiological responses in exposed organisms varied, in particular in the cases of the electron transport system, cholinesterase activity, glutathione S-transferase, catalase, and levels of total glutathione and proteins, showing that the energetic costs for detoxification and antioxidant capacity might be causing a lesser amount of energy allocated for the planarian activity. By examining the physiological, behavioural, and ecological responses of planarians to these pollutants, insights can be gained into broader ecosystem-level effects and inform strategies for mitigating environmental risks associated with OPFRs and microplastic pollution in freshwater environments.application/pdfpt_PTA Dangerous Couple: Sequential Effect of Phosphorus Flame-Retardant and Polyurethane Decrease Locomotor Activity in Planarian Girardia tigrinaPersonalBjedov, DoraDSpacehttp://dspace.org/items/16e0e553-47e2-4fdc-a965-7684bd6a8984DSpacehttp://dspace.org/items/16e0e553-47e2-4fdc-a965-7684bd6a8984BjedovDoraORCIDhttp://orcid.org0000-0003-1059-7907Barbosa, Rone S.Oliveira, Danielle Palma deDorta, Daniel JunqueiraSarmento, Maíra IgnacioSarmento, Renato AlmeidaSilva, Ana L. PatrícioPersonalGravato, CDSpacehttp://dspace.org/items/384d769e-8a9b-42e3-9c17-6ae8c24cceabDSpacehttp://dspace.org/items/384d769e-8a9b-42e3-9c17-6ae8c24cceabGravatoCarlosCiência IDhttps://www.ciencia-id.pt1414-2BF3-C834ORCIDhttp://orcid.org0000-0003-0562-6945Scopus Author IDhttps://www.scopus.com6602075076HostingInstitutionOrganizationalRepositório Científico de Acesso Aberto da ULisboae-mailmailto:repositorio@reitoria.ulisboa.ptrepositorio@reitoria.ulisboa.ptDOIIsPartOf10.3390/biology130503372024-12-19T11:48:07Z2024-052024-05-01T00:00:00ZHandlehttp://hdl.handle.net/10400.5/96494http://purl.org/coar/access_right/c_abf2open access1807138 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal article2024-05http://creativecommons.org/licenses/by/4.0/http://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://repositorio.ulisboa.pt/bitstreams/d4c6ae6d-63db-46f1-ba1a-e9e1dfd1ec88/downloadBiology135337 |
| spellingShingle | A Dangerous Couple: Sequential Effect of Phosphorus Flame-Retardant and Polyurethane Decrease Locomotor Activity in Planarian Girardia tigrina Bjedov, Dora |
| status | SINGLETON |
| title | A Dangerous Couple: Sequential Effect of Phosphorus Flame-Retardant and Polyurethane Decrease Locomotor Activity in Planarian Girardia tigrina |
| title_full | A Dangerous Couple: Sequential Effect of Phosphorus Flame-Retardant and Polyurethane Decrease Locomotor Activity in Planarian Girardia tigrina |
| title_fullStr | A Dangerous Couple: Sequential Effect of Phosphorus Flame-Retardant and Polyurethane Decrease Locomotor Activity in Planarian Girardia tigrina |
| title_full_unstemmed | A Dangerous Couple: Sequential Effect of Phosphorus Flame-Retardant and Polyurethane Decrease Locomotor Activity in Planarian Girardia tigrina |
| title_short | A Dangerous Couple: Sequential Effect of Phosphorus Flame-Retardant and Polyurethane Decrease Locomotor Activity in Planarian Girardia tigrina |
| title_sort | A Dangerous Couple: Sequential Effect of Phosphorus Flame-Retardant and Polyurethane Decrease Locomotor Activity in Planarian Girardia tigrina |
| url | http://hdl.handle.net/10400.5/96494 |
| visible | 1 |