Publicação
Metástase pancreática de adenocarcinoma do cólon : a propósito de um caso clínico
| Resumo: | Pancreatic metastasis from colorectal cancer are a rare entity, which may provide a diagnostic challenge and a plethora of controversial treatment options, in most part due to the obscure natural history of the untreated cases. In this case, we report a surgically treated pancreatic metastasis from a colorectal adenocarcinoma, apparently without extra-pancreatic involvement. In contrast with hepatic and pulmonary metastasectomy, the role of pancreatic metastasis resection is not well defined, although some groups already consider it the standard therapeutic approach when the primary tumour is under control and there is no other systemic involvement. Proper patient selection plays a key role in order to avoid a major surgery when it is unlikely to offer a significant benefit, and a preoperative assessment to exclude occult widespread metastatic disease is determinant for this selection. So far surgical results appear to be satisfactory, offering a good palliation and a reasonable medium to long term survival without excessive added mortality or morbidity related to the surgical intervention. A cure, however, is currently not expected to be more than an exceptional occurrence. |
|---|---|
| Autores principais: | Duarte, Bruno Manuel Ferreira |
| Assunto: | Metástase pancreática Cancro colo-rectal |
| Ano: | 2014 |
| País: | Portugal |
| Tipo de documento: | dissertação de mestrado |
| Tipo de acesso: | acesso restrito |
| Instituição associada: | Universidade de Lisboa |
| Idioma: | português |
| Origem: | Repositório da Universidade de Lisboa |
| Resumo: | Pancreatic metastasis from colorectal cancer are a rare entity, which may provide a diagnostic challenge and a plethora of controversial treatment options, in most part due to the obscure natural history of the untreated cases. In this case, we report a surgically treated pancreatic metastasis from a colorectal adenocarcinoma, apparently without extra-pancreatic involvement. In contrast with hepatic and pulmonary metastasectomy, the role of pancreatic metastasis resection is not well defined, although some groups already consider it the standard therapeutic approach when the primary tumour is under control and there is no other systemic involvement. Proper patient selection plays a key role in order to avoid a major surgery when it is unlikely to offer a significant benefit, and a preoperative assessment to exclude occult widespread metastatic disease is determinant for this selection. So far surgical results appear to be satisfactory, offering a good palliation and a reasonable medium to long term survival without excessive added mortality or morbidity related to the surgical intervention. A cure, however, is currently not expected to be more than an exceptional occurrence. |
|---|