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Bilirubin as a Determinant for Altered Neurogenesis, Neuritogenesis, and Synaptogenesis

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Detalhes bibliográficos
Resumo:Elevated levels of serum unconjugated bilirubin (UCB) in the first weeks of life may lead to long-term neurologic impairment. We previously reported that an early exposure of developing neurons to UCB, in conditions mimicking moderate to severe neonatal j. - Fundacao para a Ciencia e a Tecnologia (FCT) ; FEDER [POCI/SAU-MMO/55955/2004, PTDC/SAU-NEU/64385/2006, SFRH/BPD/26390/2006, SFRH/BPD/26381/2006]; EU FP6 IP FunGenES [LSHG-CT 2003-503-494]; NINDS [RO1-NS049178]. - Contract grant sponsor: Fundacao para a Ciencia e a Tecnologia (FCT). Lisbon, Portugal and FEDER: contract grant numbers: POCI/SAU-MMO/55955/2004, PTDC/SAU-NEU/64385/2006, SFRH/BPD/26390/2006. and SFRH/BPD/26381/2006. Contract grant sponsor: EU FP6 IP Fun
Autores principais:Fernandes, Adelaide
Outros Autores:Falcao, Ana Sofia; Abranches, Elsa; Bekman, Evguenia; Henrique, Domingos; Lanier, Lorene M.; Brites, Dora
Assunto:Developmental Biology Neurosciences
Ano:2009
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso a metadados
Instituição associada:Universidade de Lisboa
Idioma:inglês
Origem:Repositório da Universidade de Lisboa
Descrição
Resumo:Elevated levels of serum unconjugated bilirubin (UCB) in the first weeks of life may lead to long-term neurologic impairment. We previously reported that an early exposure of developing neurons to UCB, in conditions mimicking moderate to severe neonatal j. - Fundacao para a Ciencia e a Tecnologia (FCT) ; FEDER [POCI/SAU-MMO/55955/2004, PTDC/SAU-NEU/64385/2006, SFRH/BPD/26390/2006, SFRH/BPD/26381/2006]; EU FP6 IP FunGenES [LSHG-CT 2003-503-494]; NINDS [RO1-NS049178]. - Contract grant sponsor: Fundacao para a Ciencia e a Tecnologia (FCT). Lisbon, Portugal and FEDER: contract grant numbers: POCI/SAU-MMO/55955/2004, PTDC/SAU-NEU/64385/2006, SFRH/BPD/26390/2006. and SFRH/BPD/26381/2006. Contract grant sponsor: EU FP6 IP Fun