Publicação

Characterization of the Neuromodulatory Dysfunction in Amyotrophic Lateral Sclerosis

Detalhes bibliográficos
Autores principais:	Rei, Nádia
Assunto:	ALS SOD1G93A Adenosina A1R A2AR VEGF Brain-derived neurotrophic factor (BDNF) GABA AMPA NMDA Cafeína KW-6002 Adenosine Caffeine
Ano:	2020
País:	Portugal
Tipo de documento:	tese de doutoramento
Tipo de acesso:	acesso restrito
Instituição associada:	Universidade de Lisboa
Idioma:	inglês
Origem:	Repositório da Universidade de Lisboa

Registos relacionados

Presymptomatic and symptomatic ALS SOD1(G93A) mice differ in adenosine A1 and A2A receptor-mediated tonic modulation of neuromuscular transmission
por: Nascimento, Filipe
Publicado em: (2015)

Adenosine A2A receptor activation is determinant for BDNF actions upon GABA and glutamate release from rat hippocampal synaptosomes
por: Vaz, Sandra H.
Publicado em: (2015)

Blockade of adenosine A2A receptors prevents protein phosphorylation in the striatum induced by cortical stimulation
por: Quiroz, César
Publicado em: (2006)

Amyloid-β peptide impairs BDNF effects upon GABA release from rat synaptosomes in a calpain dependent way
por: Lérias, Sofia Ramos Rapaz
Publicado em: (2014)

The role of brain derived neurotrophic factor (BDNF) on epilepsy
por: Guimarães, Diogo Filipe Andrade
Publicado em: (2016)

Activation of adenosine A2A receptors induces TrkB translocation and increases BDNF-mediated phospho-TrkB localization in lipid rafts : implications for neuromodulation
por: Assaife-Lopes, Natália
Publicado em: (2010)

Chronic and acute adenosine A2A receptor blockade prevents long-term episodic memory disruption caused by acute cannabinoid CB1 receptor activation
por: Mouro, Francisco
Publicado em: (2017)

Amyotrophic Lateral Sclerosis with SOD1 Mutation Presenting with Progressive Cerebellar Ataxia.
por: Sequeira, Marta
Publicado em: (2024)

Synaptic plasticity in Alzheimer's disease : role of amyloid β and therapies
por: Ribeiro, Maria Filipe C. M. O.
Publicado em: (2013)

Nitric oxide mediates interactions between GABAA receptors and adenosine A1 receptors in the rat hippocampus
por: Fragata, Isabel
Publicado em: (2006)

Evaluation of promising miRNA modulation in neural cells and derived secretomes as therapeutic tools in ALS
por: Barbosa, Marta
Publicado em: (2022)

Unravelling caffeine´s influence on adult neurogenesis and behavior
por: Vares, André Vitorino de Sousa
Publicado em: (2024)

Contributo para o estudo da qualidade do grão de café da Gorongosa
por: Silva, Juliana Marreiros Duarte da
Publicado em: (2021)

GDNF control of the glutamatergic cortico-striatal pathway requires tonic activation of adenosine A2A receptors
por: Gomes, Catarina
Publicado em: (2009)

BDNF impairs recovery of synaptic transmission after hypoxia even with blockage of adenosine A2A receptors
por: Cardoso, Afonso Nobre Pinto
Publicado em: (2014)

Efeitos da administração de memantina ao longo do envelhecimento nos níveis dos recetores de BDNF
por: Carvalho, João Frederico Nóbrega
Publicado em: (2021)

Tonic activation of A2A adenosine receptors unmasks, and of A1 receptors prevents, a facilitatory action of calcitonin gene-related peptide in the rat hippocampus
por: Sebastião, Ana M
Publicado em: (2000)

Neural stem cells in multiple sclerosis : A2A receptors as a potential target
por: Porfírio, Maria Filipa Soares Mila
Publicado em: (2022)

Brain-derived neurotrophic factor facilitates glutamate and inhibits GABA release from hippocampal synaptosomes through different mechanisms
por: Canas, Nuno
Publicado em: (2004)

The RNA-binding protein hnRNP K mediates the effect of BDNF on dendritic mRNA metabolism and regulates synaptic NMDA receptors in hippocampal neurons
por: Leal, Graciano
Publicado em: (2017)

Exacerbation of C1q dysregulation, synaptic loss and memory deficits in tau pathology linked to neuronal adenosine A2A receptor
por: Carvalho, Kevin
Publicado em: (2019)

Excitatory and inhibitory effects of caffeíne in the neocortex : a transcranial magnetic stimulation study
por: Marcelino, Érica Rodrigues, 1982-
Publicado em: (2010)

Probing the synaptic target of a new putative antiepileptic drug: modulation of the excitatory transmission in the hippocampus
por: Domingos, Cátia Isabel Afonso
Publicado em: (2016)

Enhanced role of adenosine A2A receptors in the modulation of LTP in the rat hippocampus upon ageing
por: Costenla, Ana Rita
Publicado em: (2011)

Enhanced role of adenosine A2A receptors in the modulation of LTP in the rat hippocampus upon ageing
por: Costenla, Ana R.
Publicado em: (2011)

Adenosinergic system and BDNF signaling changes as a cross-sectional feature of RTT: characterization of Mecp2 heterozygous mouse females
por: Miranda-Lourenço, Catarina
Publicado em: (2023)

Hypoxia-induced desensitization and internalization of adenosine A1 receptors in the rat hippocampus
por: Coelho, Joana E
Publicado em: (2006)

Análise dos níveis plasmáticos de factores neurotróficos em doentes com diagnóstico de perturbação obsessivo-compulsiva
por: Saldanha, João Pedro Brito
Publicado em: (2020)

Role of SNARE-dependant gliotransmitter release by astrocytes on the modulation of synaptic plasticity by BDNF
por: Jesus, João Pedro de Almeida, 1993-
Publicado em: (2017)

Modulation of glutamat AMPA receptors by adenosine, in physiological and hypoxic/ischemic conditions
por: Dias, Raquel Alice da Silva Baptista, 1983-
Publicado em: (2011)

Determinant factors on hydration status assessed by urine specific gravity : accuracy of technical procedures and effect of caffeine ingestion.
por: Júdice, Pedro Alexandre Barracha da Guerra
Publicado em: (2011)

Binding of the prototypical adenosine A2A receptor agonist CGS 21680 to the cerebral cortex of adenosine A1 and A2A receptor knockout mice
por: Lopes, Luisa V.
Publicado em: (2004)

Unveiling the trophic actions of adenosine A2A receptors in neurite outgrowth and postnatal neurogenesis : interaction with brain-derived neurotrophic factor
por: Ribeiro, Ana Filipa Ferreira da Cunha, 1987-
Publicado em: (2017)

Diagnostic value of VEGF-A, VEGFR-1 and VEGFR-2 in Feline mammary carcinoma
por: Nascimento, Catarina
Publicado em: (2021)

Effects of chronic caffeine consumption on adipose tissue angiogenesis, hypoxia, and inflammation in metabolic diseases: characterization of adenosine receptors
por: Farreca, Solange Marques
Publicado em: (2021)

Impairment of adenosinergic system in Rett syndrome: novel therapeutic target to boost BDNF signalling
por: Miranda-Lourenço, Catarina
Publicado em: (2020)

Cannabinoid CB1 receptors modulation of hippocampal synaptic plasticity and the cross talk with adenosine A1 receptors
por: Cruz, Armando Dulcídio da Silva
Publicado em: (2020)

Neuroprotection afforded by adenosine A2A receptor blockade is modulated by corticotrophin-releasing factor (CRF) in glutamate injured cortical neurons
por: Valadas, Jorge S.
Publicado em: (2012)

Caffeine Effects on the Gene Expression Profile of iPSC-derived Neuronal Cells
por: Dias, Marta Isabel Silva
Publicado em: (2017)

Deciphering the mechanisms underlying the loss of BDNF neuroprotection in an Alzheimer’s disease model
por: Tanqueiro, Sara Luísa Ramalho, 1992-
Publicado em: (2016)