Publicação
The prevalence of dementia in a Portuguese community sample : a 10/66 Dementia Research Group study
| Resumo: | Background: Dementia imposes a high burden of disease worldwide. Recent epidemiological studies in European community samples are scarce. In Portugal, community prevalence data is very limited. The 10/66 Dementia Research Group (DRG) population-based research programmes are focused in low and middle income countries, where the assessments proved to be culture and education fair. We applied the 10/66 DRG prevalence survey methodology in Portugal, where levels of illiteracy in older populations are still high. Methods: A cross-sectional comprehensive one-phase survey was conducted of all residents aged 65 and over of two geographically defined catchment areas in Southern Portugal (one urban and one rural site). Nursing home residents were not included in the present study. Standardized 10/66 DRG assessments include a cognitive module, an informant interview and the Geriatric Mental State-AGECAT, providing data on dementia diagnosis and subtypes, mental disorders including depression, physical health, anthropometry, demographics, disability/functioning, health service utilization, care arrangements and caregiver strain. Results: We interviewed 1405 old age participants (mean age 74.9, SD = 6.7 years; 55.5% women) after 313 (18.2%) refusals to participate. The prevalence rate for dementia in community-dwellers was 9.23% (95% CI 7.80–10.90) using the 10/66 DRG algorithm and 3.65% (95% CI 2.97–4.97) using DSM-IV criteria. Pure Alzheimer’s disease was the most prevalent dementia subtype (41.9%). The prevalence of dementia was strongly age-dependent for both criteria, but there was no association with sex. Conclusions: Dementia prevalence was higher than previously reported in Portugal. The discrepancy between prevalence according to the 10/66 DRG algorithm and the DSM-IV criteria is consistent with that observed in less developed countries; this suggests potential underestimation using the latter approach, although relative validity of these two approaches remains to be confirmed in the European context. We improved the evidence base to raise awareness and empower advocacy about dementia in Portugal, so that the complex needs of frail older people may be met in better ways. |
|---|---|
| Autores principais: | Pereira, Manuel Gonçalves |
| Outros Autores: | Cardoso, Ana; Verdelho, Ana; Silva, Joaquim Alves da; Almeida, Manuel Caldas de; Fernandes, Alexandra; Raminhos, Cátia; Ferri, Cleusa P.; Prina, A. Matthew; Prince, Martin; Xavier, Miguel |
| Assunto: | Dementia Alzheimer’s disease Epidemiology Prevalence Questionnaires Cross-cultural psychiatry |
| Ano: | 2017 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade de Lisboa |
| Idioma: | inglês |
| Origem: | Repositório da Universidade de Lisboa |
| _version_ | 1866810471760265216 |
|---|---|
| author | Pereira, Manuel Gonçalves |
| author2 | Cardoso, Ana Verdelho, Ana Silva, Joaquim Alves da Almeida, Manuel Caldas de Fernandes, Alexandra Raminhos, Cátia Ferri, Cleusa P. Prina, A. Matthew Prince, Martin Xavier, Miguel |
| author2_role | author author author author author author author author author author |
| author_facet | Pereira, Manuel Gonçalves Cardoso, Ana Verdelho, Ana Silva, Joaquim Alves da Almeida, Manuel Caldas de Fernandes, Alexandra Raminhos, Cátia Ferri, Cleusa P. Prina, A. Matthew Prince, Martin Xavier, Miguel |
| author_role | author |
| contributor_name_str_mv | Repositório Científico de Acesso Aberto da ULisboa |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Pereira, Manuel Gonçalves\"},{\"Person.name\":\"Cardoso, Ana\"},{\"Person.name\":\"Verdelho, Ana\"},{\"Person.name\":\"Silva, Joaquim Alves da\"},{\"Person.name\":\"Almeida, Manuel Caldas de\"},{\"Person.name\":\"Fernandes, Alexandra\"},{\"Person.name\":\"Raminhos, Cátia\"},{\"Person.name\":\"Ferri, Cleusa P.\"},{\"Person.name\":\"Prina, A. Matthew\"},{\"Person.name\":\"Prince, Martin\"},{\"Person.name\":\"Xavier, Miguel\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Repositório Científico de Acesso Aberto da ULisboa |
| datacite.creators.creator.creatorName.fl_str_mv | Pereira, Manuel Gonçalves Cardoso, Ana Verdelho, Ana Silva, Joaquim Alves da Almeida, Manuel Caldas de Fernandes, Alexandra Raminhos, Cátia Ferri, Cleusa P. Prina, A. Matthew Prince, Martin Xavier, Miguel |
| datacite.date.Accepted.fl_str_mv | 2017-01-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2017-11-21T16:18:00Z |
| datacite.date.embargoed.fl_str_mv | 2017-11-21T16:18:00Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Dementia Alzheimer’s disease Epidemiology Prevalence Questionnaires Cross-cultural psychiatry |
| datacite.titles.title.fl_str_mv | The prevalence of dementia in a Portuguese community sample : a 10/66 Dementia Research Group study |
| dc.contributor.none.fl_str_mv | Repositório Científico de Acesso Aberto da ULisboa |
| dc.creator.none.fl_str_mv | Pereira, Manuel Gonçalves Cardoso, Ana Verdelho, Ana Silva, Joaquim Alves da Almeida, Manuel Caldas de Fernandes, Alexandra Raminhos, Cátia Ferri, Cleusa P. Prina, A. Matthew Prince, Martin Xavier, Miguel |
| dc.date.Accepted.fl_str_mv | 2017-01-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2017-11-21T16:18:00Z |
| dc.date.embargoed.fl_str_mv | 2017-11-21T16:18:00Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | http://hdl.handle.net/10451/29828 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | BioMed Central |
| dc.rights.cclincense.fl_str_mv | http://creativecommons.org/licenses/by/4.0/ |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | Dementia Alzheimer’s disease Epidemiology Prevalence Questionnaires Cross-cultural psychiatry |
| dc.title.fl_str_mv | The prevalence of dementia in a Portuguese community sample : a 10/66 Dementia Research Group study |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Background: Dementia imposes a high burden of disease worldwide. Recent epidemiological studies in European community samples are scarce. In Portugal, community prevalence data is very limited. The 10/66 Dementia Research Group (DRG) population-based research programmes are focused in low and middle income countries, where the assessments proved to be culture and education fair. We applied the 10/66 DRG prevalence survey methodology in Portugal, where levels of illiteracy in older populations are still high. Methods: A cross-sectional comprehensive one-phase survey was conducted of all residents aged 65 and over of two geographically defined catchment areas in Southern Portugal (one urban and one rural site). Nursing home residents were not included in the present study. Standardized 10/66 DRG assessments include a cognitive module, an informant interview and the Geriatric Mental State-AGECAT, providing data on dementia diagnosis and subtypes, mental disorders including depression, physical health, anthropometry, demographics, disability/functioning, health service utilization, care arrangements and caregiver strain. Results: We interviewed 1405 old age participants (mean age 74.9, SD = 6.7 years; 55.5% women) after 313 (18.2%) refusals to participate. The prevalence rate for dementia in community-dwellers was 9.23% (95% CI 7.80–10.90) using the 10/66 DRG algorithm and 3.65% (95% CI 2.97–4.97) using DSM-IV criteria. Pure Alzheimer’s disease was the most prevalent dementia subtype (41.9%). The prevalence of dementia was strongly age-dependent for both criteria, but there was no association with sex. Conclusions: Dementia prevalence was higher than previously reported in Portugal. The discrepancy between prevalence according to the 10/66 DRG algorithm and the DSM-IV criteria is consistent with that observed in less developed countries; this suggests potential underestimation using the latter approach, although relative validity of these two approaches remains to be confirmed in the European context. We improved the evidence base to raise awareness and empower advocacy about dementia in Portugal, so that the complex needs of frail older people may be met in better ways. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| fulltext.url.fl_str_mv | https://repositorio.ulisboa.pt/bitstreams/5a8a6abe-9df7-4559-9fcf-29051cbe8f68/download |
| id | ul_a2e4bdc359e86edb85661abdf618bb6d |
| identifier.url.fl_str_mv | http://hdl.handle.net/10451/29828 |
| instacron_str | ul |
| institution | Universidade de Lisboa |
| instname_str | Universidade de Lisboa |
| language | eng |
| network_acronym_str | ul |
| network_name_str | Repositório da Universidade de Lisboa |
| oai_identifier_str | oai:repositorio.ulisboa.pt:10451/29828 |
| organization_str_mv | urn:organizationAcronym:ul |
| person_str_mv | Pereira, Manuel Gonçalves Cardoso, Ana Verdelho, Ana Silva, Joaquim Alves da Almeida, Manuel Caldas de Fernandes, Alexandra Raminhos, Cátia Ferri, Cleusa P. Prina, A. Matthew Prince, Martin Xavier, Miguel |
| publishDate | 2017 |
| publisher.none.fl_str_mv | BioMed Central |
| reponame_str | Repositório da Universidade de Lisboa |
| repository_id_str | urn:repositoryAcronym:ul |
| service_str_mv | urn:repositoryAcronym:ul |
| spelling | engBioMed Centralpt_PTBackground: Dementia imposes a high burden of disease worldwide. Recent epidemiological studies in European community samples are scarce. In Portugal, community prevalence data is very limited. The 10/66 Dementia Research Group (DRG) population-based research programmes are focused in low and middle income countries, where the assessments proved to be culture and education fair. We applied the 10/66 DRG prevalence survey methodology in Portugal, where levels of illiteracy in older populations are still high. Methods: A cross-sectional comprehensive one-phase survey was conducted of all residents aged 65 and over of two geographically defined catchment areas in Southern Portugal (one urban and one rural site). Nursing home residents were not included in the present study. Standardized 10/66 DRG assessments include a cognitive module, an informant interview and the Geriatric Mental State-AGECAT, providing data on dementia diagnosis and subtypes, mental disorders including depression, physical health, anthropometry, demographics, disability/functioning, health service utilization, care arrangements and caregiver strain. Results: We interviewed 1405 old age participants (mean age 74.9, SD = 6.7 years; 55.5% women) after 313 (18.2%) refusals to participate. The prevalence rate for dementia in community-dwellers was 9.23% (95% CI 7.80–10.90) using the 10/66 DRG algorithm and 3.65% (95% CI 2.97–4.97) using DSM-IV criteria. Pure Alzheimer’s disease was the most prevalent dementia subtype (41.9%). The prevalence of dementia was strongly age-dependent for both criteria, but there was no association with sex. Conclusions: Dementia prevalence was higher than previously reported in Portugal. The discrepancy between prevalence according to the 10/66 DRG algorithm and the DSM-IV criteria is consistent with that observed in less developed countries; this suggests potential underestimation using the latter approach, although relative validity of these two approaches remains to be confirmed in the European context. We improved the evidence base to raise awareness and empower advocacy about dementia in Portugal, so that the complex needs of frail older people may be met in better ways.application/pdfpt_PTThe prevalence of dementia in a Portuguese community sample : a 10/66 Dementia Research Group studyPereira, Manuel GonçalvesCardoso, AnaVerdelho, AnaSilva, Joaquim Alves daAlmeida, Manuel Caldas deFernandes, AlexandraRaminhos, CátiaFerri, Cleusa P.Prina, A. MatthewPrince, MartinXavier, MiguelHostingInstitutionOrganizationalRepositório Científico de Acesso Aberto da ULisboae-mailmailto:repositorio@reitoria.ulisboa.ptrepositorio@reitoria.ulisboa.ptISSNIsPartOf1471-2318DOIIsPartOf10.1186/s12877-017-0647-52017-11-21T16:18:00Z20172017-01-01T00:00:00ZHandlehttp://hdl.handle.net/10451/29828http://purl.org/coar/access_right/c_abf2open accessDementiaAlzheimer’s diseaseEpidemiologyPrevalenceQuestionnairesCross-cultural psychiatry471969 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal article2017http://creativecommons.org/licenses/by/4.0/http://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://repositorio.ulisboa.pt/bitstreams/5a8a6abe-9df7-4559-9fcf-29051cbe8f68/downloadBMC Geriatrics171261 |
| spellingShingle | The prevalence of dementia in a Portuguese community sample : a 10/66 Dementia Research Group study Pereira, Manuel Gonçalves Dementia Alzheimer’s disease Epidemiology Prevalence Questionnaires Cross-cultural psychiatry |
| status | SINGLETON |
| subject.fl_str_mv | Dementia Alzheimer’s disease Epidemiology Prevalence Questionnaires Cross-cultural psychiatry |
| title | The prevalence of dementia in a Portuguese community sample : a 10/66 Dementia Research Group study |
| title_full | The prevalence of dementia in a Portuguese community sample : a 10/66 Dementia Research Group study |
| title_fullStr | The prevalence of dementia in a Portuguese community sample : a 10/66 Dementia Research Group study |
| title_full_unstemmed | The prevalence of dementia in a Portuguese community sample : a 10/66 Dementia Research Group study |
| title_short | The prevalence of dementia in a Portuguese community sample : a 10/66 Dementia Research Group study |
| title_sort | The prevalence of dementia in a Portuguese community sample : a 10/66 Dementia Research Group study |
| topic | Dementia Alzheimer’s disease Epidemiology Prevalence Questionnaires Cross-cultural psychiatry |
| topic_facet | Dementia Alzheimer’s disease Epidemiology Prevalence Questionnaires Cross-cultural psychiatry |
| url | http://hdl.handle.net/10451/29828 |
| visible | 1 |