Publicação
Further labdane and kaurane diterpenoids and other constituents from Plectranthus fruticosus
| Resumo: | Eight new diterpenoids, one labdane and seven kaurane derivatives, and a new aromadendrane-type sesquiterpenoid have been isolated from the most polar chromatographic fractions of an acetone extract of Plectranthus fruticosus. The structures of the new compounds (1-9) were established mainly by ID and 2D NMR studies and by some chemical transformations. Compounds 6 and 8 were characterized as their methyl ester derivatives (13 and 14, respectively). Most of the isolated compounds and some of their derivatives were tested as antimicrobial agents, but only 19 showed moderate inhibitory activity against Staphylococcus aureus. |
|---|---|
| Autores principais: | Gaspar-Marques, C |
| Outros Autores: | Simoes, MF; Rodriguez, B |
| Assunto: | Plant Sciences Chemistry, Medicinal Pharmacology & Pharmacy |
| Ano: | 2004 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso a metadados |
| Instituição associada: | Universidade de Lisboa |
| Idioma: | inglês |
| Origem: | Repositório da Universidade de Lisboa |
| _version_ | 1866810733567672320 |
|---|---|
| author | Gaspar-Marques, C |
| author2 | Simoes, MF Rodriguez, B |
| author2_role | author author |
| author_facet | Gaspar-Marques, C Simoes, MF Rodriguez, B |
| author_role | author |
| contributor_name_str_mv | Repositório Científico de Acesso Aberto da ULisboa |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Gaspar-Marques, C\"},{\"Person.name\":\"Simoes, MF\"},{\"Person.name\":\"Rodriguez, B\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Repositório Científico de Acesso Aberto da ULisboa |
| datacite.creators.creator.creatorName.fl_str_mv | Gaspar-Marques, C Simoes, MF Rodriguez, B |
| datacite.date.Accepted.fl_str_mv | 2004-01-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2015-12-30T10:17:34Z |
| datacite.date.embargoed.fl_str_mv | 2015-12-30T10:17:34Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_14cb |
| datacite.subjects.subject.fl_str_mv | Plant Sciences Chemistry, Medicinal Pharmacology & Pharmacy |
| datacite.titles.title.fl_str_mv | Further labdane and kaurane diterpenoids and other constituents from Plectranthus fruticosus |
| dc.contributor.none.fl_str_mv | Repositório Científico de Acesso Aberto da ULisboa |
| dc.creator.none.fl_str_mv | Gaspar-Marques, C Simoes, MF Rodriguez, B |
| dc.date.Accepted.fl_str_mv | 2004-01-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2015-12-30T10:17:34Z |
| dc.date.embargoed.fl_str_mv | 2015-12-30T10:17:34Z |
| dc.identifier.none.fl_str_mv | http://hdl.handle.net/10451/21132 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | AMER CHEMICAL SOC |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_14cb |
| dc.subject.none.fl_str_mv | Plant Sciences Chemistry, Medicinal Pharmacology & Pharmacy |
| dc.title.fl_str_mv | Further labdane and kaurane diterpenoids and other constituents from Plectranthus fruticosus |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Eight new diterpenoids, one labdane and seven kaurane derivatives, and a new aromadendrane-type sesquiterpenoid have been isolated from the most polar chromatographic fractions of an acetone extract of Plectranthus fruticosus. The structures of the new compounds (1-9) were established mainly by ID and 2D NMR studies and by some chemical transformations. Compounds 6 and 8 were characterized as their methyl ester derivatives (13 and 14, respectively). Most of the isolated compounds and some of their derivatives were tested as antimicrobial agents, but only 19 showed moderate inhibitory activity against Staphylococcus aureus. |
| dirty | 0 |
| eu_rights_str_mv | metadataOnlyAccess |
| format | article |
| id | ul_c48008064f4dfd9a5a4e207a3d7e9e1f |
| identifier.url.fl_str_mv | http://hdl.handle.net/10451/21132 |
| instacron_str | ul |
| institution | Universidade de Lisboa |
| instname_str | Universidade de Lisboa |
| language | eng |
| network_acronym_str | ul |
| network_name_str | Repositório da Universidade de Lisboa |
| oai_identifier_str | oai:repositorio.ulisboa.pt:10451/21132 |
| organization_str_mv | urn:organizationAcronym:ul |
| person_str_mv | Gaspar-Marques, C Simoes, MF Rodriguez, B |
| publishDate | 2004 |
| publisher.none.fl_str_mv | AMER CHEMICAL SOC |
| reponame_str | Repositório da Universidade de Lisboa |
| repository_id_str | urn:repositoryAcronym:ul |
| service_str_mv | urn:repositoryAcronym:ul |
| spelling | engAMER CHEMICAL SOCEight new diterpenoids, one labdane and seven kaurane derivatives, and a new aromadendrane-type sesquiterpenoid have been isolated from the most polar chromatographic fractions of an acetone extract of Plectranthus fruticosus. The structures of the new compounds (1-9) were established mainly by ID and 2D NMR studies and by some chemical transformations. Compounds 6 and 8 were characterized as their methyl ester derivatives (13 and 14, respectively). Most of the isolated compounds and some of their derivatives were tested as antimicrobial agents, but only 19 showed moderate inhibitory activity against Staphylococcus aureus.Further labdane and kaurane diterpenoids and other constituents from Plectranthus fruticosusGaspar-Marques, CSimoes, MFRodriguez, BHostingInstitutionOrganizationalRepositório Científico de Acesso Aberto da ULisboae-mailmailto:repositorio@reitoria.ulisboa.ptrepositorio@reitoria.ulisboa.ptISSNIsPartOf0163-3864DOIIsPartOfhttp://dx.doi.org/10.1021/np030490j2015-12-30T10:17:34Z20042004-01-01T00:00:00ZHandlehttp://hdl.handle.net/10451/21132http://purl.org/coar/access_right/c_14cbmetadata only accessPlant SciencesChemistry, MedicinalPharmacology & Pharmacyliteraturehttp://purl.org/coar/resource_type/c_6501journal articleJOURNAL OF NATURAL PRODUCTSVol. 67614621 |
| spellingShingle | Further labdane and kaurane diterpenoids and other constituents from Plectranthus fruticosus Gaspar-Marques, C Plant Sciences Chemistry, Medicinal Pharmacology & Pharmacy |
| status | SINGLETON |
| subject.fl_str_mv | Plant Sciences Chemistry, Medicinal Pharmacology & Pharmacy |
| title | Further labdane and kaurane diterpenoids and other constituents from Plectranthus fruticosus |
| title_full | Further labdane and kaurane diterpenoids and other constituents from Plectranthus fruticosus |
| title_fullStr | Further labdane and kaurane diterpenoids and other constituents from Plectranthus fruticosus |
| title_full_unstemmed | Further labdane and kaurane diterpenoids and other constituents from Plectranthus fruticosus |
| title_short | Further labdane and kaurane diterpenoids and other constituents from Plectranthus fruticosus |
| title_sort | Further labdane and kaurane diterpenoids and other constituents from Plectranthus fruticosus |
| topic | Plant Sciences Chemistry, Medicinal Pharmacology & Pharmacy |
| topic_facet | Plant Sciences Chemistry, Medicinal Pharmacology & Pharmacy |
| url | http://hdl.handle.net/10451/21132 |
| visible | 1 |