Publicação
Diabetes mellitus e osteoporose
| Resumo: | This review is entitled “Diabetes Mellitus and Osteoporosis” and it focus the relationship between both pathologies, either Diabetes Mellitus secondary Osteoporosis, as well as Osteoporosis and Diabetes as comorbidities that lead to an increase in fracture risk, regarding the biological mechanisms that influence one and the other. Although diabetic metabolic changes are potential factors that influence bone metabolism and structure, as well as bone mineral density, their contribution to the fracture risk increment verified in individuals with both diabetes mellitus type 1 an type 2 is still subject of debate. A search has been made on the PubMed database, essentially literature written in the last 6/7 years that included Diabetes and Osteoporosis, with emphasis on bone metabolism but not leaving out fracture risk assessment. Additionally, the evidence based guidelines published by several international organizations had been appreciated too. The characteristic aspects of Diabetes Mellitus type 2 are focused, but some specifications of Diabetes Mellitus type 1 are also taken in consideration for the holisic comprehension of this pathology. |
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| Autores principais: | Sanches, Tiago André Ferreira |
| Assunto: | Diabetes mellitus Osteoporose Risco de fractura |
| Ano: | 2014 |
| País: | Portugal |
| Tipo de documento: | dissertação de mestrado |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade de Lisboa |
| Idioma: | português |
| Origem: | Repositório da Universidade de Lisboa |
| Resumo: | This review is entitled “Diabetes Mellitus and Osteoporosis” and it focus the relationship between both pathologies, either Diabetes Mellitus secondary Osteoporosis, as well as Osteoporosis and Diabetes as comorbidities that lead to an increase in fracture risk, regarding the biological mechanisms that influence one and the other. Although diabetic metabolic changes are potential factors that influence bone metabolism and structure, as well as bone mineral density, their contribution to the fracture risk increment verified in individuals with both diabetes mellitus type 1 an type 2 is still subject of debate. A search has been made on the PubMed database, essentially literature written in the last 6/7 years that included Diabetes and Osteoporosis, with emphasis on bone metabolism but not leaving out fracture risk assessment. Additionally, the evidence based guidelines published by several international organizations had been appreciated too. The characteristic aspects of Diabetes Mellitus type 2 are focused, but some specifications of Diabetes Mellitus type 1 are also taken in consideration for the holisic comprehension of this pathology. |
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