Publicação
Dietary Ulva lactuca and CAZyme supplementation improve serum biochemical profile and hepatic composition of weaned piglets
| Resumo: | Ulva lactuca is a seaweed with antinutritional cell wall for monogastrics. Carbohydrate-Active enZymes (CAZymes) supplementation can potentially cause its disruption. This study evaluates four diets: Ctrl—control diet; UL—control + 7% U. lactuca (wild caught, powdered form); ULR—UL + 0.005% Rovabio® Excel AP; ULU—UL + 0.01% ulvan lyase on piglets’ haematologic and serologic profiles, hepatic lipids and minerals. White blood cells and lymphocytes reached the highest values in piglets fed UL compared to control, and to control and ULR; respectively (P < 0.05). IgG levels were boosted by seaweed incorporation compared to control (P = 0.015). The glycaemic homeostasis was assured by the seaweed inclusion. Dietary seaweed decreased serum lipids (P < 0.001), with the exception of ULU, due to HDL-cholesterol increase (P < 0.001). Cortisol was decreased in ULR and ULU (P < 0.001). No systemic inflammation was observed (P > 0.05). While hepatic n-3 PUFA increased in piglets fed with seaweed diets due to increment of beneficial 22:5n-3 and 22:6n-3 fatty acids (P < 0.05), the opposite occurred for n-6 PUFA, PUFA/SFA and n-6/n-3 ratios (P < 0.05). Hepatic pigments were unchanged (P > 0.05). ULR reduced α-tocopherol levels (P = 0.036) and increased serum potassium levels (P < 0.001) compared to control. Seaweed contributed to overcome piglets’ weaning stress, with some benefits of including CAZyme supplementation. |
|---|---|
| Autores principais: | Ribeiro, David M. |
| Outros Autores: | Lopes, Paula A.; Pinto, Rui M. A.; Pestana, José M.; Costa, Mónica M.; Alfaia, Cristina M.; Mourato, Miguel; Almeida, André; Freire, João; Prates, José A. M. |
| Ano: | 2023 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade de Lisboa |
| Idioma: | inglês |
| Origem: | Repositório da Universidade de Lisboa |
| _version_ | 1866809480284471296 |
|---|---|
| author | Ribeiro, David M. |
| author2 | Lopes, Paula A. Pinto, Rui M. A. Pestana, José M. Costa, Mónica M. Alfaia, Cristina M. Mourato, Miguel Almeida, André Freire, João Prates, José A. M. |
| author2_role | author author author author author author author author author |
| author_facet | Ribeiro, David M. Lopes, Paula A. Pinto, Rui M. A. Pestana, José M. Costa, Mónica M. Alfaia, Cristina M. Mourato, Miguel Almeida, André Freire, João Prates, José A. M. |
| author_role | author |
| contributor_name_str_mv | Repositório Científico de Acesso Aberto da ULisboa |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Ribeiro, David M.\"},{\"Person.name\":\"Lopes, Paula A.\"},{\"Person.name\":\"Pinto, Rui M. A.\"},{\"Person.name\":\"Pestana, José M.\"},{\"Person.name\":\"Costa, Mónica M.\"},{\"Person.name\":\"Alfaia, Cristina M.\"},{\"Person.name\":\"Mourato, Miguel\",\"Person.identifier.orcid\":\"0000-0003-4843-1064\"},{\"Person.name\":\"Almeida, André\",\"Person.identifier.orcid\":\"0000-0002-7810-3988\"},{\"Person.name\":\"Freire, João\",\"Person.identifier.orcid\":\"0000-0002-1811-4378\"},{\"Person.name\":\"Prates, José A. M.\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Repositório Científico de Acesso Aberto da ULisboa |
| datacite.creators.creator.creatorName.fl_str_mv | Ribeiro, David M. Lopes, Paula A. Pinto, Rui M. A. Pestana, José M. Costa, Mónica M. Alfaia, Cristina M. Mourato, Miguel Almeida, André Freire, João Prates, José A. M. |
| datacite.date.Accepted.fl_str_mv | 2023-12-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2024-07-22T18:33:16Z |
| datacite.date.embargoed.fl_str_mv | 2024-07-22T18:33:16Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.titles.title.fl_str_mv | Dietary Ulva lactuca and CAZyme supplementation improve serum biochemical profile and hepatic composition of weaned piglets |
| dc.contributor.none.fl_str_mv | Repositório Científico de Acesso Aberto da ULisboa |
| dc.creator.none.fl_str_mv | Ribeiro, David M. Lopes, Paula A. Pinto, Rui M. A. Pestana, José M. Costa, Mónica M. Alfaia, Cristina M. Mourato, Miguel Almeida, André Freire, João Prates, José A. M. |
| dc.date.Accepted.fl_str_mv | 2023-12-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2024-07-22T18:33:16Z |
| dc.date.embargoed.fl_str_mv | 2024-07-22T18:33:16Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | http://hdl.handle.net/10400.5/31340 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Nature |
| dc.rights.cclincense.fl_str_mv | http://creativecommons.org/licenses/by/4.0/ |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.title.fl_str_mv | Dietary Ulva lactuca and CAZyme supplementation improve serum biochemical profile and hepatic composition of weaned piglets |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Ulva lactuca is a seaweed with antinutritional cell wall for monogastrics. Carbohydrate-Active enZymes (CAZymes) supplementation can potentially cause its disruption. This study evaluates four diets: Ctrl—control diet; UL—control + 7% U. lactuca (wild caught, powdered form); ULR—UL + 0.005% Rovabio® Excel AP; ULU—UL + 0.01% ulvan lyase on piglets’ haematologic and serologic profiles, hepatic lipids and minerals. White blood cells and lymphocytes reached the highest values in piglets fed UL compared to control, and to control and ULR; respectively (P < 0.05). IgG levels were boosted by seaweed incorporation compared to control (P = 0.015). The glycaemic homeostasis was assured by the seaweed inclusion. Dietary seaweed decreased serum lipids (P < 0.001), with the exception of ULU, due to HDL-cholesterol increase (P < 0.001). Cortisol was decreased in ULR and ULU (P < 0.001). No systemic inflammation was observed (P > 0.05). While hepatic n-3 PUFA increased in piglets fed with seaweed diets due to increment of beneficial 22:5n-3 and 22:6n-3 fatty acids (P < 0.05), the opposite occurred for n-6 PUFA, PUFA/SFA and n-6/n-3 ratios (P < 0.05). Hepatic pigments were unchanged (P > 0.05). ULR reduced α-tocopherol levels (P = 0.036) and increased serum potassium levels (P < 0.001) compared to control. Seaweed contributed to overcome piglets’ weaning stress, with some benefits of including CAZyme supplementation. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| fulltext.url.fl_str_mv | https://repositorio.ulisboa.pt/bitstreams/a26dc751-6dd6-449f-be5c-e22cf89a0d79/download |
| id | ul_ec2e776c8a07ff28947bae625ec8beec |
| identifier.url.fl_str_mv | http://hdl.handle.net/10400.5/31340 |
| instacron_str | ul |
| institution | Universidade de Lisboa |
| instname_str | Universidade de Lisboa |
| language | eng |
| network_acronym_str | ul |
| network_name_str | Repositório da Universidade de Lisboa |
| oai_identifier_str | oai:repositorio.ulisboa.pt:10400.5/31340 |
| organization_str_mv | urn:organizationAcronym:ul |
| person_str_mv | Ribeiro, David M. Lopes, Paula A. Pinto, Rui M. A. Pestana, José M. Costa, Mónica M. Alfaia, Cristina M. Mourato, Miguel Mourato, Miguel https://www.ciencia-id.pt/3D1E-4003-BF64 3D1E-4003-BF64 http://orcid.org/0000-0003-4843-1064 0000-0003-4843-1064 Almeida, André Almeida, André https://www.ciencia-id.pt/1E14-92CC-B163 1E14-92CC-B163 http://orcid.org/0000-0002-7810-3988 0000-0002-7810-3988 Freire, João Freire, João https://www.ciencia-id.pt/871A-F6C8-60FE 871A-F6C8-60FE http://orcid.org/0000-0002-1811-4378 0000-0002-1811-4378 Prates, José A. M. |
| publishDate | 2023 |
| publisher.none.fl_str_mv | Nature |
| reponame_str | Repositório da Universidade de Lisboa |
| repository_id_str | urn:repositoryAcronym:ul |
| service_str_mv | urn:repositoryAcronym:ul |
| spelling | engNaturept_PTUlva lactuca is a seaweed with antinutritional cell wall for monogastrics. Carbohydrate-Active enZymes (CAZymes) supplementation can potentially cause its disruption. This study evaluates four diets: Ctrl—control diet; UL—control + 7% U. lactuca (wild caught, powdered form); ULR—UL + 0.005% Rovabio® Excel AP; ULU—UL + 0.01% ulvan lyase on piglets’ haematologic and serologic profiles, hepatic lipids and minerals. White blood cells and lymphocytes reached the highest values in piglets fed UL compared to control, and to control and ULR; respectively (P < 0.05). IgG levels were boosted by seaweed incorporation compared to control (P = 0.015). The glycaemic homeostasis was assured by the seaweed inclusion. Dietary seaweed decreased serum lipids (P < 0.001), with the exception of ULU, due to HDL-cholesterol increase (P < 0.001). Cortisol was decreased in ULR and ULU (P < 0.001). No systemic inflammation was observed (P > 0.05). While hepatic n-3 PUFA increased in piglets fed with seaweed diets due to increment of beneficial 22:5n-3 and 22:6n-3 fatty acids (P < 0.05), the opposite occurred for n-6 PUFA, PUFA/SFA and n-6/n-3 ratios (P < 0.05). Hepatic pigments were unchanged (P > 0.05). ULR reduced α-tocopherol levels (P = 0.036) and increased serum potassium levels (P < 0.001) compared to control. Seaweed contributed to overcome piglets’ weaning stress, with some benefits of including CAZyme supplementation.application/pdfpt_PTDietary Ulva lactuca and CAZyme supplementation improve serum biochemical profile and hepatic composition of weaned pigletsRibeiro, David M.Lopes, Paula A.Pinto, Rui M. A.Pestana, José M.Costa, Mónica M.Alfaia, Cristina M.PersonalMourato, MiguelDSpacehttp://dspace.org/items/f3e8b80c-0f8e-42bb-a85c-078de348063bDSpacehttp://dspace.org/items/f3e8b80c-0f8e-42bb-a85c-078de348063bMouratoMiguelCiência IDhttps://www.ciencia-id.pt3D1E-4003-BF64ORCIDhttp://orcid.org0000-0003-4843-1064Researcher IDhttps://www.researcherid.comB-6904-2009Scopus Author IDhttps://www.scopus.com56370610300PersonalAlmeida, AndréDSpacehttp://dspace.org/items/722b3039-6553-4059-8e11-d5eaf113a8cdDSpacehttp://dspace.org/items/722b3039-6553-4059-8e11-d5eaf113a8cdMartinho de AlmeidaAndréCiência IDhttps://www.ciencia-id.pt1E14-92CC-B163ORCIDhttp://orcid.org0000-0002-7810-3988PersonalFreire, JoãoDSpacehttp://dspace.org/items/99660917-13cd-47e0-bf7d-667497ebcfbeDSpacehttp://dspace.org/items/99660917-13cd-47e0-bf7d-667497ebcfbeBengala FreireJoão PedroCiência IDhttps://www.ciencia-id.pt871A-F6C8-60FEORCIDhttp://orcid.org0000-0002-1811-4378Prates, José A. M.HostingInstitutionOrganizationalRepositório Científico de Acesso Aberto da ULisboae-mailmailto:repositorio@reitoria.ulisboa.ptrepositorio@reitoria.ulisboa.ptDOIIsPartOf10.1038/s41598-023-36008-42024-07-22T18:33:16Z2023-122023-12-01T00:00:00ZHandlehttp://hdl.handle.net/10400.5/31340http://purl.org/coar/access_right/c_abf2open access1451692 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal article2023-12http://creativecommons.org/licenses/by/4.0/http://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://repositorio.ulisboa.pt/bitstreams/a26dc751-6dd6-449f-be5c-e22cf89a0d79/downloadScientific Reports131Article number 8784 |
| spellingShingle | Dietary Ulva lactuca and CAZyme supplementation improve serum biochemical profile and hepatic composition of weaned piglets Ribeiro, David M. |
| status | SINGLETON |
| title | Dietary Ulva lactuca and CAZyme supplementation improve serum biochemical profile and hepatic composition of weaned piglets |
| title_full | Dietary Ulva lactuca and CAZyme supplementation improve serum biochemical profile and hepatic composition of weaned piglets |
| title_fullStr | Dietary Ulva lactuca and CAZyme supplementation improve serum biochemical profile and hepatic composition of weaned piglets |
| title_full_unstemmed | Dietary Ulva lactuca and CAZyme supplementation improve serum biochemical profile and hepatic composition of weaned piglets |
| title_short | Dietary Ulva lactuca and CAZyme supplementation improve serum biochemical profile and hepatic composition of weaned piglets |
| title_sort | Dietary Ulva lactuca and CAZyme supplementation improve serum biochemical profile and hepatic composition of weaned piglets |
| url | http://hdl.handle.net/10400.5/31340 |
| visible | 1 |