Publicação
Recompensa alimentar : mecanismos envolvidos e implicações para a obesidade
| Resumo: | Obesity is on the rise in many industrialized countries, and a large part of this epidemic phenomenon is attributed to overeating induced by ubiquitous highly palatable and high energy density food cues. The ability to maintain adequate nutrient intake is critical for survival. Due to this, complex interrelated neuronal circuits have been developed in the mammalian brain to regulate many aspects of the feeding behavior. There are certain strong homeostatic mechanisms that are regulated by the hypothalamus and the brainstem, which sustain body weight. However, in the current “obesogenic” environment, food intake is largely determined by non-homeostatic or hedonic factors, primarily processed in corticolimbicand higher cortical brain regions. This paper presents a review that describes the mechanisms responsible for the processing of food reward, the interaction between homeostatic and reward mechanisms, as well as its implications in hyperphagia and obesity. |
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| Autores principais: | Ribeiro, Gabriela |
| Outros Autores: | Santos, Osvaldo |
| Assunto: | Obesity Hedonic Food reward |
| Ano: | 2013 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso restrito |
| Instituição associada: | Universidade de Lisboa |
| Idioma: | português |
| Origem: | Repositório da Universidade de Lisboa |
| Resumo: | Obesity is on the rise in many industrialized countries, and a large part of this epidemic phenomenon is attributed to overeating induced by ubiquitous highly palatable and high energy density food cues. The ability to maintain adequate nutrient intake is critical for survival. Due to this, complex interrelated neuronal circuits have been developed in the mammalian brain to regulate many aspects of the feeding behavior. There are certain strong homeostatic mechanisms that are regulated by the hypothalamus and the brainstem, which sustain body weight. However, in the current “obesogenic” environment, food intake is largely determined by non-homeostatic or hedonic factors, primarily processed in corticolimbicand higher cortical brain regions. This paper presents a review that describes the mechanisms responsible for the processing of food reward, the interaction between homeostatic and reward mechanisms, as well as its implications in hyperphagia and obesity. |
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