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Weil’s disease in an urban setting : a case report

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Resumo:Leptospirosis is a worldwide zoonotic infectious disease with a broad and nonspecific clinical presentation. The milder form usually expresses as subclinical and self-limited anicteric febrile illness and full recovery is the rule. However, a much less common but life-threating form - known as Weil’s disease – typically presents as fever, jaundice and renal failure and was first described by Weil in 1886. In 1915, the causative agent of Weil’s disease was finally internationally announced as being Leptospira icterohaemorrhagiae. A century after its discovery, much more is known about Weil's disease agent, pathogenesis and treatment. Even so, leptospirosis still comes to international attention as a globally important re-emerging infectious disease. I report a case of Weil’s disease in an urban area presenting as fever, jaundice and progressive leg weakness, complicating with acute pancreatitis and impaired kidney function. Renal replacement therapy and transfusion support were eventually required.
Autores principais:Carragosela, Ricardo Alexandre Davide
Assunto:Leptospirose Doença de Weil Icterícia febril aguda lesão renal aguda
Ano:2015
País:Portugal
Tipo de documento:dissertação de mestrado
Tipo de acesso:acesso restrito
Instituição associada:Universidade de Lisboa
Idioma:inglês
Origem:Repositório da Universidade de Lisboa
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author Carragosela, Ricardo Alexandre Davide
author_facet Carragosela, Ricardo Alexandre Davide
author_role author
contributor_name_str_mv Oliveira, Anabela Furtado Mendes de
Repositório Científico de Acesso Aberto da ULisboa
country_str PT
creators_json_txt [{\"Person.name\":\"Carragosela, Ricardo Alexandre Davide\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Oliveira, Anabela Furtado Mendes de
Repositório Científico de Acesso Aberto da ULisboa
datacite.creators.creator.creatorName.fl_str_mv Carragosela, Ricardo Alexandre Davide
datacite.date.Accepted.fl_str_mv 2015-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2017-01-19T15:13:47Z
datacite.date.embargoed.fl_str_mv 2017-01-19T15:13:47Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_16ec
datacite.subjects.subject.fl_str_mv Leptospirose
Doença de Weil
Icterícia febril aguda
lesão renal aguda
datacite.titles.title.fl_str_mv Weil’s disease in an urban setting : a case report
dc.contributor.none.fl_str_mv Oliveira, Anabela Furtado Mendes de
Repositório Científico de Acesso Aberto da ULisboa
dc.creator.none.fl_str_mv Carragosela, Ricardo Alexandre Davide
dc.date.Accepted.fl_str_mv 2015-01-01T00:00:00Z
dc.date.available.fl_str_mv 2017-01-19T15:13:47Z
dc.date.embargoed.fl_str_mv 2017-01-19T15:13:47Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10451/26044
dc.language.none.fl_str_mv eng
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_16ec
dc.subject.none.fl_str_mv Leptospirose
Doença de Weil
Icterícia febril aguda
lesão renal aguda
dc.title.fl_str_mv Weil’s disease in an urban setting : a case report
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_bdcc
description Leptospirosis is a worldwide zoonotic infectious disease with a broad and nonspecific clinical presentation. The milder form usually expresses as subclinical and self-limited anicteric febrile illness and full recovery is the rule. However, a much less common but life-threating form - known as Weil’s disease – typically presents as fever, jaundice and renal failure and was first described by Weil in 1886. In 1915, the causative agent of Weil’s disease was finally internationally announced as being Leptospira icterohaemorrhagiae. A century after its discovery, much more is known about Weil's disease agent, pathogenesis and treatment. Even so, leptospirosis still comes to international attention as a globally important re-emerging infectious disease. I report a case of Weil’s disease in an urban area presenting as fever, jaundice and progressive leg weakness, complicating with acute pancreatitis and impaired kidney function. Renal replacement therapy and transfusion support were eventually required.
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id ul_ffecbb2394747bd2eebbc7130a16c7f1
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instacron_str ul
institution Universidade de Lisboa
instname_str Universidade de Lisboa
language eng
network_acronym_str ul
network_name_str Repositório da Universidade de Lisboa
oai_identifier_str oai:repositorio.ulisboa.pt:10451/26044
organization_str_mv urn:organizationAcronym:ul
person_str_mv Carragosela, Ricardo Alexandre Davide
publishDate 2015
reponame_str Repositório da Universidade de Lisboa
repository_id_str urn:repositoryAcronym:ul
service_str_mv urn:repositoryAcronym:ul
spelling engpt_PTLeptospirosis is a worldwide zoonotic infectious disease with a broad and nonspecific clinical presentation. The milder form usually expresses as subclinical and self-limited anicteric febrile illness and full recovery is the rule. However, a much less common but life-threating form - known as Weil’s disease – typically presents as fever, jaundice and renal failure and was first described by Weil in 1886. In 1915, the causative agent of Weil’s disease was finally internationally announced as being Leptospira icterohaemorrhagiae. A century after its discovery, much more is known about Weil's disease agent, pathogenesis and treatment. Even so, leptospirosis still comes to international attention as a globally important re-emerging infectious disease. I report a case of Weil’s disease in an urban area presenting as fever, jaundice and progressive leg weakness, complicating with acute pancreatitis and impaired kidney function. Renal replacement therapy and transfusion support were eventually required.application/pdfpt_PTWeil’s disease in an urban setting : a case reportCarragosela, Ricardo Alexandre DavideOliveira, Anabela Furtado Mendes deHostingInstitutionOrganizationalRepositório Científico de Acesso Aberto da ULisboae-mailmailto:repositorio@reitoria.ulisboa.ptrepositorio@reitoria.ulisboa.ptURNurn:tid:2010594872017-01-19T15:13:47Z20152015-01-01T00:00:00ZHandlehttp://hdl.handle.net/10451/26044http://purl.org/coar/access_right/c_16ecrestricted accessLeptospiroseDoença de WeilIcterícia febril agudalesão renal aguda583688 bytesliteraturehttp://purl.org/coar/resource_type/c_bdccmaster thesishttp://purl.org/coar/access_right/c_16ecapplication/pdffulltexthttps://repositorio.ulisboa.pt/bitstreams/83c1277c-ba61-4a21-822d-a0a7b4f09e46/download
spellingShingle Weil’s disease in an urban setting : a case report
Carragosela, Ricardo Alexandre Davide
Leptospirose
Doença de Weil
Icterícia febril aguda
lesão renal aguda
status SINGLETON
subject.fl_str_mv Leptospirose
Doença de Weil
Icterícia febril aguda
lesão renal aguda
title Weil’s disease in an urban setting : a case report
title_full Weil’s disease in an urban setting : a case report
title_fullStr Weil’s disease in an urban setting : a case report
title_full_unstemmed Weil’s disease in an urban setting : a case report
title_short Weil’s disease in an urban setting : a case report
title_sort Weil’s disease in an urban setting : a case report
topic Leptospirose
Doença de Weil
Icterícia febril aguda
lesão renal aguda
topic_facet Leptospirose
Doença de Weil
Icterícia febril aguda
lesão renal aguda
url http://hdl.handle.net/10451/26044
visible 1