Publicação
Hematology, Serum Biochemistry and Serum Protein Electrophoresis Ranges for European hedgehog (Erinaceus europaeus) in Northern Portugal
| Resumo: | The European hedgehog (Erinaceus europaeus) is an insectivorous mammal with a wide geographic distribution. Due mostly to climate changes and anthropogenic pressures, a considerable number of hedgehogs lives now in urban areas close to humans where they are exposed to contaminants and biological agents that may result in disease with the correspondent hematological and biochemical alterations. Hedgehogs can work as bioindicators of environmental pollution and be hosts for multiple zoonotic agents making it relevant in terms of One Health studies. It’s essential to deepen the knowledge of this species calculating the reference intervals (RI) for the usual hematological and biochemical determinations. That way it would be possible recognize the “normal” and identify the “disease”. The main objective of this work was to conduct a study of hematology, biochemistry and protein electrophoresis in the species Erinaceus europaeus in order to calculate reference intervals. For this study, the registry of the Clinical Pathology Laboratory (LPC) of the Veterinary Teaching Hospital of the University of Trás-os-Montes and Alto Douro (HVUTAD) between March 2017 and August 2022 was analyzed. Data of hematology, clinical biochemistry, and protein electrophoresis from 37 healthy hedgehogs of HVUTAD Rehabilitation Center (CRAS-HVUTAD) was included (13 males, 22 females, 2 of unknown sex; 20 juveniles, 14 adults, 3 of unknown age). Reference Value Advisor V2.1 was used for RI calculation. It was possible to calculate RI for almost all the variables in study. Also, the sex and age effect were investigated, and statistically significant differences were obtained between the respective groups in the following parameters: Alkaline Phosphatase (p = 0.012, higher in males); Total Proteins (p = 0.034, higher in adults); Mean Cell Volume (p = 0.007) and Mean Corpuscular Hemoglobin (p = 0.010) (both higher in juveniles) and Red Blood Cell Distribution Width (p = 0.021, higher in adults). In this study, some significant differences were evident, especially when comparing age groups (juveniles versus adults), showing the relevance of further studies in this species. It allowed, for the first time, to define RI for a population of hedgehogs in Portugal, having a potentially relevant impact on species conservation and in the human-animal health interface. |
|---|---|
| Autores principais: | Rosa, Sofia Alexandra Silva |
| Assunto: | European hedgehog Erinaceus europaeus |
| Ano: | 2023 |
| País: | Portugal |
| Tipo de documento: | dissertação de mestrado |
| Tipo de acesso: | acesso restrito |
| Instituição associada: | Universidade de Trás-os-Montes e Alto Douro |
| Idioma: | inglês |
| Origem: | Repositório da UTAD |
| _version_ | 1865920860486893568 |
|---|---|
| author | Rosa, Sofia Alexandra Silva |
| author_facet | Rosa, Sofia Alexandra Silva Rosa, Sofia Alexandra Silva |
| author_role | author |
| contributor.other.fl_str_mv | Ferreira, Ana Cristina Silvestre Queiroga, Felisbina |
| contributor_name_str_mv | Ferreira, Ana Cristina Silvestre Queiroga, Felisbina Repositório Institucional da UTAD |
| country_str | PT |
| creators_json_str | [{\"Person.name\":\"Rosa, Sofia Alexandra Silva\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Ferreira, Ana Cristina Silvestre Queiroga, Felisbina Repositório Institucional da UTAD |
| datacite.creators.creator.creatorName.fl_str_mv | Rosa, Sofia Alexandra Silva |
| datacite.date.Accepted.fl_str_mv | 2023-03-03T00:00:00Z |
| datacite.date.available.fl_str_mv | 2023-11-22T16:36:22Z |
| datacite.date.embargoed.fl_str_mv | 2023-11-22T16:36:22Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_16ec |
| datacite.subjects.subject.fl_str_mv | European hedgehog Erinaceus europaeus |
| datacite.titles.title.fl_str_mv | Hematology, Serum Biochemistry and Serum Protein Electrophoresis Ranges for European hedgehog (Erinaceus europaeus) in Northern Portugal |
| dc.contributor.none.fl_str_mv | Ferreira, Ana Cristina Silvestre Queiroga, Felisbina Repositório Institucional da UTAD |
| dc.creator.none.fl_str_mv | Rosa, Sofia Alexandra Silva |
| dc.date.Accepted.fl_str_mv | 2023-03-03T00:00:00Z |
| dc.date.available.fl_str_mv | 2023-11-22T16:36:22Z |
| dc.date.embargoed.fl_str_mv | 2023-11-22T16:36:22Z |
| dc.format.none.fl_str_mv | application/pdf application/pdf application/pdf |
| dc.identifier.none.fl_str_mv | http://hdl.handle.net/10348/11959 |
| dc.language.none.fl_str_mv | eng |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_16ec |
| dc.subject.none.fl_str_mv | European hedgehog Erinaceus europaeus |
| dc.title.fl_str_mv | Hematology, Serum Biochemistry and Serum Protein Electrophoresis Ranges for European hedgehog (Erinaceus europaeus) in Northern Portugal |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_bdcc |
| description | The European hedgehog (Erinaceus europaeus) is an insectivorous mammal with a wide geographic distribution. Due mostly to climate changes and anthropogenic pressures, a considerable number of hedgehogs lives now in urban areas close to humans where they are exposed to contaminants and biological agents that may result in disease with the correspondent hematological and biochemical alterations. Hedgehogs can work as bioindicators of environmental pollution and be hosts for multiple zoonotic agents making it relevant in terms of One Health studies. It’s essential to deepen the knowledge of this species calculating the reference intervals (RI) for the usual hematological and biochemical determinations. That way it would be possible recognize the “normal” and identify the “disease”. The main objective of this work was to conduct a study of hematology, biochemistry and protein electrophoresis in the species Erinaceus europaeus in order to calculate reference intervals. For this study, the registry of the Clinical Pathology Laboratory (LPC) of the Veterinary Teaching Hospital of the University of Trás-os-Montes and Alto Douro (HVUTAD) between March 2017 and August 2022 was analyzed. Data of hematology, clinical biochemistry, and protein electrophoresis from 37 healthy hedgehogs of HVUTAD Rehabilitation Center (CRAS-HVUTAD) was included (13 males, 22 females, 2 of unknown sex; 20 juveniles, 14 adults, 3 of unknown age). Reference Value Advisor V2.1 was used for RI calculation. It was possible to calculate RI for almost all the variables in study. Also, the sex and age effect were investigated, and statistically significant differences were obtained between the respective groups in the following parameters: Alkaline Phosphatase (p = 0.012, higher in males); Total Proteins (p = 0.034, higher in adults); Mean Cell Volume (p = 0.007) and Mean Corpuscular Hemoglobin (p = 0.010) (both higher in juveniles) and Red Blood Cell Distribution Width (p = 0.021, higher in adults). In this study, some significant differences were evident, especially when comparing age groups (juveniles versus adults), showing the relevance of further studies in this species. It allowed, for the first time, to define RI for a population of hedgehogs in Portugal, having a potentially relevant impact on species conservation and in the human-animal health interface. |
| dirty | 0 |
| eu_rights_str_mv | restrictedAccess |
| format | masterThesis |
| fulltext.url.fl_str_mv | https://repositorio.utad.pt/bitstreams/6774daeb-f43e-441c-8ce3-2f31db9f7f8e/download |
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| identifier.url.fl_str_mv | http://hdl.handle.net/10348/11959 |
| instacron_str | utad |
| institution | Universidade de Trás-os-Montes e Alto Douro |
| instname_str | Universidade de Trás-os-Montes e Alto Douro |
| language | eng |
| network_acronym_str | utad |
| network_name_str | Repositório da UTAD |
| oai_identifier_str | oai:repositorio.utad.pt:10348/11959 |
| organization_str_mv | urn:organizationAcronym:utad |
| person_str_mv | Rosa, Sofia Alexandra Silva Ferreira, Ana Cristina Silvestre Ferreira, Ana Cristina Silvestre https://www.ciencia-id.pt/C71E-BBCC-03B4 C71E-BBCC-03B4 http://orcid.org/0000-0002-7114-6918 0000-0002-7114-6918 Queiroga, Felisbina Queiroga, Felisbina https://www.ciencia-id.pt/781C-113F-EEBC 781C-113F-EEBC http://orcid.org/0000-0001-6130-8381 0000-0001-6130-8381 |
| publishDate | 2023 |
| reponame_str | Repositório da UTAD |
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| spelling | engpt_PTThe European hedgehog (Erinaceus europaeus) is an insectivorous mammal with a wide geographic distribution. Due mostly to climate changes and anthropogenic pressures, a considerable number of hedgehogs lives now in urban areas close to humans where they are exposed to contaminants and biological agents that may result in disease with the correspondent hematological and biochemical alterations. Hedgehogs can work as bioindicators of environmental pollution and be hosts for multiple zoonotic agents making it relevant in terms of One Health studies. It’s essential to deepen the knowledge of this species calculating the reference intervals (RI) for the usual hematological and biochemical determinations. That way it would be possible recognize the “normal” and identify the “disease”. The main objective of this work was to conduct a study of hematology, biochemistry and protein electrophoresis in the species Erinaceus europaeus in order to calculate reference intervals. For this study, the registry of the Clinical Pathology Laboratory (LPC) of the Veterinary Teaching Hospital of the University of Trás-os-Montes and Alto Douro (HVUTAD) between March 2017 and August 2022 was analyzed. Data of hematology, clinical biochemistry, and protein electrophoresis from 37 healthy hedgehogs of HVUTAD Rehabilitation Center (CRAS-HVUTAD) was included (13 males, 22 females, 2 of unknown sex; 20 juveniles, 14 adults, 3 of unknown age). Reference Value Advisor V2.1 was used for RI calculation. It was possible to calculate RI for almost all the variables in study. Also, the sex and age effect were investigated, and statistically significant differences were obtained between the respective groups in the following parameters: Alkaline Phosphatase (p = 0.012, higher in males); Total Proteins (p = 0.034, higher in adults); Mean Cell Volume (p = 0.007) and Mean Corpuscular Hemoglobin (p = 0.010) (both higher in juveniles) and Red Blood Cell Distribution Width (p = 0.021, higher in adults). In this study, some significant differences were evident, especially when comparing age groups (juveniles versus adults), showing the relevance of further studies in this species. It allowed, for the first time, to define RI for a population of hedgehogs in Portugal, having a potentially relevant impact on species conservation and in the human-animal health interface.application/pdfapplication/pdfapplication/pdfpt_PTHematology, Serum Biochemistry and Serum Protein Electrophoresis Ranges for European hedgehog (Erinaceus europaeus) in Northern PortugalRosa, Sofia Alexandra SilvaOtherPersonalFerreira, Ana Cristina SilvestreAna Cristina SilvestreFerreiraUTAD-DCVScopus Author IDhttps://www.scopus.com7801335462Ciência IDhttps://www.ciencia-id.ptC71E-BBCC-03B4ORCIDhttp://orcid.org0000-0002-7114-6918OtherPersonalQueiroga, FelisbinaFelisbina Luisa Pereira GuedesQueirogaUTAD-DCVScopus Author IDhttps://www.scopus.com9332477900Ciência IDhttps://www.ciencia-id.pt781C-113F-EEBCORCIDhttp://orcid.org0000-0001-6130-8381Researcher IDhttps://www.researcherid.comL-5169-2013HostingInstitutionOrganizationalRepositório Institucional da UTADe-mailmailto:jborges@utad.ptjborges@utad.pt2023-11-22T16:36:22Z2023-03-032023-03-03T00:00:00ZHandlehttp://hdl.handle.net/10348/11959http://purl.org/coar/access_right/c_16ecrestricted accessEuropean hedgehogErinaceus europaeus278272 bytes1418442 bytes11414424 bytesliteraturehttp://purl.org/coar/resource_type/c_bdccmaster thesishttp://purl.org/coar/access_right/c_16ecapplication/pdffulltexthttps://repositorio.utad.pt/bitstreams/6774daeb-f43e-441c-8ce3-2f31db9f7f8e/downloadhttp://purl.org/coar/access_right/c_16ecapplication/pdffulltexthttps://repositorio.utad.pt/bitstreams/df7f8ba1-551c-4b7a-b3e8-c2618bf3e156/downloadhttp://purl.org/coar/access_right/c_16ecapplication/pdffulltexthttps://repositorio.utad.pt/bitstreams/7bef68c9-78d6-4a2a-9f37-9b6baf2c4dfd/download |
| spellingShingle | Hematology, Serum Biochemistry and Serum Protein Electrophoresis Ranges for European hedgehog (Erinaceus europaeus) in Northern Portugal Hematology, Serum Biochemistry and Serum Protein Electrophoresis Ranges for European hedgehog (Erinaceus europaeus) in Northern Portugal Rosa, Sofia Alexandra Silva European hedgehog Erinaceus europaeus Rosa, Sofia Alexandra Silva European hedgehog Erinaceus europaeus |
| status | NEW |
| subject.fl_str_mv | European hedgehog Erinaceus europaeus |
| title | Hematology, Serum Biochemistry and Serum Protein Electrophoresis Ranges for European hedgehog (Erinaceus europaeus) in Northern Portugal |
| title_full | Hematology, Serum Biochemistry and Serum Protein Electrophoresis Ranges for European hedgehog (Erinaceus europaeus) in Northern Portugal |
| title_fullStr | Hematology, Serum Biochemistry and Serum Protein Electrophoresis Ranges for European hedgehog (Erinaceus europaeus) in Northern Portugal Hematology, Serum Biochemistry and Serum Protein Electrophoresis Ranges for European hedgehog (Erinaceus europaeus) in Northern Portugal |
| title_full_unstemmed | Hematology, Serum Biochemistry and Serum Protein Electrophoresis Ranges for European hedgehog (Erinaceus europaeus) in Northern Portugal Hematology, Serum Biochemistry and Serum Protein Electrophoresis Ranges for European hedgehog (Erinaceus europaeus) in Northern Portugal |
| title_short | Hematology, Serum Biochemistry and Serum Protein Electrophoresis Ranges for European hedgehog (Erinaceus europaeus) in Northern Portugal |
| title_sort | Hematology, Serum Biochemistry and Serum Protein Electrophoresis Ranges for European hedgehog (Erinaceus europaeus) in Northern Portugal |
| topic | European hedgehog Erinaceus europaeus |
| topic_facet | European hedgehog Erinaceus europaeus |
| url | http://hdl.handle.net/10348/11959 |
| visible | 1 |