Publicação

Effect of mannan oligosaccharides on the ileal morphometry and cecal fermentation of growing rabbits

Ver documento

Detalhes bibliográficos
Resumo:A common problem in rabbits is the occurrence of digestive disorders just after weaning. This problem is usually associated with instability of the cecal microflora and characterized by diarrhea, loss of appetite and increased mortality. In the current study the effects of a mannan oligosaccharide (MOS, Bio-MOS ® , Alltech Inc. USA) was compared to a commonly used antibiotic (AGP, Zn-Bacitracin). The current study investigated the effects of MOS and AGP on intestinal morphometry and cecal VFA production. A total of 220 weaned mixed-sex rabbits (32d) were divided into 5 experimental treatments and housed in groups of 4 in 55 flat deck cages located in an experimental rabbit house. The 5 experimental treatments were as follow: Control (no additives);MOS 1 (1 kg MOS/t); MOS 1.5 (1.5 kg MOS/t); MOS 2 (2 kg MOS/t) and AGP (0.1 kg/t). Experimental diets were based on alfalfa, sunflower meal and wheat and beet pulp and were offered ad libitum through out the experiment. Intestinal morphology and cecal fermentation was determined in 8 rabbits per treatment slaughtered at day 46. Histologic examination showed significantly longer villi (P<0.05) in rabbits fed MOS (503.1, 518.6 and 508.8 for MOS 1, MOS 1.5 and MOS 2, respectively) or AGP (502.5) compared to the control group (403.0). This was also translated into a numerically increased absorption surface. Cecal volatile fatty acid (VFA) concentration differed significantly (P<0.05) between treatments. Rabbits fed MOS at 1 kg/t had the highest total VFA concentration (98.02 vs. 51.57 in MOS 1 and Control) and higher butyric acid (14.09 vs. 4.59 in MOS 1 and Control). Furthermore cecal pH was significantly lower in rabbits fed MOS at 1 kg/t and 2 kg/t (5.79 and 5.92) compared to the control (6.33). Results for this study suggest that MOS has a stimulating effect on villi development and production of cecal VFA and reduce cecal pH, which could improve the health status of growing rabbits.
Autores principais:Pinto, L.
Outros Autores:Spring, Peter; Kocher, A.; Alves, Anabela; Mourão, J. L.; Pinheiro, Victor; Guedes, Cristina
Assunto:Rabbit Mannan oligosaccharide Villi length VFA
Ano:2004
País:Portugal
Tipo de documento:documento de conferência
Tipo de acesso:acesso aberto
Instituição associada:Universidade de Trás-os-Montes e Alto Douro
Idioma:inglês
Origem:Repositório da UTAD
_version_ 1865920872372502528
author Pinto, L.
author2 Spring, Peter
Kocher, A.
Alves, Anabela
Mourão, J. L.
Pinheiro, Victor
Guedes, Cristina
author2_role author
author
author
author
author
author
author_facet Pinto, L.
Pinto, L.
Spring, Peter
Kocher, A.
Alves, Anabela
Mourão, J. L.
Pinheiro, Victor
Guedes, Cristina
Spring, Peter
Kocher, A.
Alves, Anabela
Mourão, J. L.
Pinheiro, Victor
Guedes, Cristina
author_role author
contributor_name_str_mv Repositório Institucional da UTAD
country_str PT
creators_json_str [{\"Person.name\":\"Pinto, L.\"},{\"Person.name\":\"Spring, Peter\"},{\"Person.name\":\"Kocher, A.\"},{\"Person.name\":\"Alves, Anabela\",\"Person.identifier.orcid\":\"0000-0002-0800-5717\"},{\"Person.name\":\"Mourão, J. L.\",\"Person.identifier.orcid\":\"0000-0003-0804-2945\"},{\"Person.name\":\"Pinheiro, Victor\",\"Person.identifier.orcid\":\"0000-0003-3052-6989\"},{\"Person.name\":\"Guedes, Cristina\",\"Person.identifier.orcid\":\"0000-0002-8390-4907\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Repositório Institucional da UTAD
datacite.creators.creator.creatorName.fl_str_mv Pinto, L.
Spring, Peter
Kocher, A.
Alves, Anabela
Mourão, J. L.
Pinheiro, Victor
Guedes, Cristina
datacite.date.Accepted.fl_str_mv 2004-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2013-08-19T10:19:58Z
datacite.date.embargoed.fl_str_mv 2013-08-19T10:19:58Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Rabbit
Mannan oligosaccharide
Villi length
VFA
datacite.titles.title.fl_str_mv Effect of mannan oligosaccharides on the ileal morphometry and cecal fermentation of growing rabbits
dc.contributor.none.fl_str_mv Repositório Institucional da UTAD
dc.creator.none.fl_str_mv Pinto, L.
Spring, Peter
Kocher, A.
Alves, Anabela
Mourão, J. L.
Pinheiro, Victor
Guedes, Cristina
dc.date.Accepted.fl_str_mv 2004-01-01T00:00:00Z
dc.date.available.fl_str_mv 2013-08-19T10:19:58Z
dc.date.embargoed.fl_str_mv 2013-08-19T10:19:58Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10348/2570
dc.language.none.fl_str_mv eng
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.subject.none.fl_str_mv Rabbit
Mannan oligosaccharide
Villi length
VFA
dc.title.fl_str_mv Effect of mannan oligosaccharides on the ileal morphometry and cecal fermentation of growing rabbits
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_c94f
description A common problem in rabbits is the occurrence of digestive disorders just after weaning. This problem is usually associated with instability of the cecal microflora and characterized by diarrhea, loss of appetite and increased mortality. In the current study the effects of a mannan oligosaccharide (MOS, Bio-MOS ® , Alltech Inc. USA) was compared to a commonly used antibiotic (AGP, Zn-Bacitracin). The current study investigated the effects of MOS and AGP on intestinal morphometry and cecal VFA production. A total of 220 weaned mixed-sex rabbits (32d) were divided into 5 experimental treatments and housed in groups of 4 in 55 flat deck cages located in an experimental rabbit house. The 5 experimental treatments were as follow: Control (no additives);MOS 1 (1 kg MOS/t); MOS 1.5 (1.5 kg MOS/t); MOS 2 (2 kg MOS/t) and AGP (0.1 kg/t). Experimental diets were based on alfalfa, sunflower meal and wheat and beet pulp and were offered ad libitum through out the experiment. Intestinal morphology and cecal fermentation was determined in 8 rabbits per treatment slaughtered at day 46. Histologic examination showed significantly longer villi (P<0.05) in rabbits fed MOS (503.1, 518.6 and 508.8 for MOS 1, MOS 1.5 and MOS 2, respectively) or AGP (502.5) compared to the control group (403.0). This was also translated into a numerically increased absorption surface. Cecal volatile fatty acid (VFA) concentration differed significantly (P<0.05) between treatments. Rabbits fed MOS at 1 kg/t had the highest total VFA concentration (98.02 vs. 51.57 in MOS 1 and Control) and higher butyric acid (14.09 vs. 4.59 in MOS 1 and Control). Furthermore cecal pH was significantly lower in rabbits fed MOS at 1 kg/t and 2 kg/t (5.79 and 5.92) compared to the control (6.33). Results for this study suggest that MOS has a stimulating effect on villi development and production of cecal VFA and reduce cecal pH, which could improve the health status of growing rabbits.
dirty 0
eu_rights_str_mv openAccess
format conferenceObject
fulltext.url.fl_str_mv https://repositorio.utad.pt/bitstreams/0fd56bb8-39f0-4497-b5fe-bedadd96b51a/download
id utad_dbfd26c0b213e9db6cb4e196d6749e7c
identifier.url.fl_str_mv http://hdl.handle.net/10348/2570
instacron_str utad
institution Universidade de Trás-os-Montes e Alto Douro
instname_str Universidade de Trás-os-Montes e Alto Douro
language eng
network_acronym_str utad
network_name_str Repositório da UTAD
oai_identifier_str oai:repositorio.utad.pt:10348/2570
organization_str_mv urn:organizationAcronym:utad
person_str_mv Pinto, L.
Spring, Peter
Kocher, A.
Alves, Anabela
Alves, Anabela
https://www.ciencia-id.pt/0B1B-723B-A09D
0B1B-723B-A09D
http://orcid.org/0000-0002-0800-5717
0000-0002-0800-5717
Mourão, J. L.
Mourão, J. L.
https://www.ciencia-id.pt/CE1E-FE48-8E3E
CE1E-FE48-8E3E
http://orcid.org/0000-0003-0804-2945
0000-0003-0804-2945
Pinheiro, Victor
Pinheiro, Victor
https://www.ciencia-id.pt/1F15-858D-2321
1F15-858D-2321
http://orcid.org/0000-0003-3052-6989
0000-0003-3052-6989
Guedes, Cristina
Guedes, Cristina
https://www.ciencia-id.pt/A41F-CF2A-8E0D
A41F-CF2A-8E0D
http://orcid.org/0000-0002-8390-4907
0000-0002-8390-4907
publishDate 2004
reponame_str Repositório da UTAD
repository_id_str urn:repositoryAcronym:utad
service_str_mv urn:repositoryAcronym:utad
spelling engporA common problem in rabbits is the occurrence of digestive disorders just after weaning. This problem is usually associated with instability of the cecal microflora and characterized by diarrhea, loss of appetite and increased mortality. In the current study the effects of a mannan oligosaccharide (MOS, Bio-MOS ® , Alltech Inc. USA) was compared to a commonly used antibiotic (AGP, Zn-Bacitracin). The current study investigated the effects of MOS and AGP on intestinal morphometry and cecal VFA production. A total of 220 weaned mixed-sex rabbits (32d) were divided into 5 experimental treatments and housed in groups of 4 in 55 flat deck cages located in an experimental rabbit house. The 5 experimental treatments were as follow: Control (no additives);MOS 1 (1 kg MOS/t); MOS 1.5 (1.5 kg MOS/t); MOS 2 (2 kg MOS/t) and AGP (0.1 kg/t). Experimental diets were based on alfalfa, sunflower meal and wheat and beet pulp and were offered ad libitum through out the experiment. Intestinal morphology and cecal fermentation was determined in 8 rabbits per treatment slaughtered at day 46. Histologic examination showed significantly longer villi (P<0.05) in rabbits fed MOS (503.1, 518.6 and 508.8 for MOS 1, MOS 1.5 and MOS 2, respectively) or AGP (502.5) compared to the control group (403.0). This was also translated into a numerically increased absorption surface. Cecal volatile fatty acid (VFA) concentration differed significantly (P<0.05) between treatments. Rabbits fed MOS at 1 kg/t had the highest total VFA concentration (98.02 vs. 51.57 in MOS 1 and Control) and higher butyric acid (14.09 vs. 4.59 in MOS 1 and Control). Furthermore cecal pH was significantly lower in rabbits fed MOS at 1 kg/t and 2 kg/t (5.79 and 5.92) compared to the control (6.33). Results for this study suggest that MOS has a stimulating effect on villi development and production of cecal VFA and reduce cecal pH, which could improve the health status of growing rabbits.application/pdfporEffect of mannan oligosaccharides on the ileal morphometry and cecal fermentation of growing rabbitsPinto, L.Spring, PeterKocher, A.PersonalAlves, AnabelaDSpacehttp://dspace.org/items/27aa4e02-25c0-43d6-a2f7-30e5161c84e7DSpacehttp://dspace.org/items/27aa4e02-25c0-43d6-a2f7-30e5161c84e7Anabela Gouveia AntunesAlvesUTAD-DCVScopus Author IDhttps://www.scopus.com26021744000Ciência IDhttps://www.ciencia-id.pt0B1B-723B-A09DORCIDhttp://orcid.org0000-0002-0800-5717Researcher IDhttps://www.researcherid.comK-4204-2013PersonalMourão, J. L.DSpacehttp://dspace.org/items/b40c62ce-ae96-42b6-8b40-5962ecffee68DSpacehttp://dspace.org/items/b40c62ce-ae96-42b6-8b40-5962ecffee68José Luis Teixeira de Abreu de MedeirosMourãoUTAD-DZOOScopus Author IDhttps://www.scopus.com14030387800Ciência IDhttps://www.ciencia-id.ptCE1E-FE48-8E3EORCIDhttp://orcid.org0000-0003-0804-2945Researcher IDhttps://www.researcherid.comK-5557-2013PersonalPinheiro, VictorDSpacehttp://dspace.org/items/06267d35-3ca5-4001-85cd-51404b29b597DSpacehttp://dspace.org/items/06267d35-3ca5-4001-85cd-51404b29b597Victor Manuel CarvalhoPinheiroUTAD-DZOOScopus Author IDhttps://www.scopus.com22942171100Scopus Author IDhttps://www.scopus.com57204654433Ciência IDhttps://www.ciencia-id.pt1F15-858D-2321ORCIDhttp://orcid.org0000-0003-3052-6989Researcher IDhttps://www.researcherid.comK-4256-2013PersonalGuedes, CristinaDSpacehttp://dspace.org/items/5a05ec27-c37c-4971-a937-6fd092ff2d79DSpacehttp://dspace.org/items/5a05ec27-c37c-4971-a937-6fd092ff2d79Cristina Vitória de MirandaGuedesScopus Author IDhttps://www.scopus.com8538193900Ciência IDhttps://www.ciencia-id.ptA41F-CF2A-8E0DORCIDhttp://orcid.org0000-0002-8390-4907Researcher IDhttps://www.researcherid.comK-2986-2013HostingInstitutionOrganizationalRepositório Institucional da UTADe-mailmailto:jborges@utad.ptjborges@utad.pt2013-08-19T10:19:58Z20042004-01-01T00:00:00ZHandlehttp://hdl.handle.net/10348/2570http://purl.org/coar/access_right/c_abf2open accessRabbitMannan oligosaccharideVilli lengthVFA451736 bytesother research producthttp://purl.org/coar/resource_type/c_c94fconference objecthttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://repositorio.utad.pt/bitstreams/0fd56bb8-39f0-4497-b5fe-bedadd96b51a/download
spellingShingle Effect of mannan oligosaccharides on the ileal morphometry and cecal fermentation of growing rabbits
Effect of mannan oligosaccharides on the ileal morphometry and cecal fermentation of growing rabbits
Pinto, L.
Rabbit
Mannan oligosaccharide
Villi length
VFA
Pinto, L.
Rabbit
Mannan oligosaccharide
Villi length
VFA
status NEW
subject.fl_str_mv Rabbit
Mannan oligosaccharide
Villi length
VFA
title Effect of mannan oligosaccharides on the ileal morphometry and cecal fermentation of growing rabbits
title_full Effect of mannan oligosaccharides on the ileal morphometry and cecal fermentation of growing rabbits
title_fullStr Effect of mannan oligosaccharides on the ileal morphometry and cecal fermentation of growing rabbits
Effect of mannan oligosaccharides on the ileal morphometry and cecal fermentation of growing rabbits
title_full_unstemmed Effect of mannan oligosaccharides on the ileal morphometry and cecal fermentation of growing rabbits
Effect of mannan oligosaccharides on the ileal morphometry and cecal fermentation of growing rabbits
title_short Effect of mannan oligosaccharides on the ileal morphometry and cecal fermentation of growing rabbits
title_sort Effect of mannan oligosaccharides on the ileal morphometry and cecal fermentation of growing rabbits
topic Rabbit
Mannan oligosaccharide
Villi length
VFA
topic_facet Rabbit
Mannan oligosaccharide
Villi length
VFA
url http://hdl.handle.net/10348/2570
visible 1